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Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis

Hepatology (Baltimore, Md.), 2007-06, Vol.45 (6), p.1366-1374

2007

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Peripheral Androgen Receptor Gene Suppression Rescues Disease in Mouse Models of Spinal and Bulbar Muscular Atrophy

Cell reports (Cambridge), 2014-05, Vol.7 (3), p.774-784

2014

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Suppression of Diacylglycerol Acyltransferase-2 (DGAT2), but Not DGAT1, with Antisense Oligonucleotides Reverses Diet-induced Hepatic Steatosis and Insulin Resistance

The Journal of biological chemistry, 2007-08, Vol.282 (31), p.22678-22688

2007

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SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats

Proceedings of the National Academy of Sciences - PNAS, 2009-07, Vol.106 (27), p.11288-11293

2009

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Peripheral reduction of FGFR4 with antisense oligonucleotides increases metabolic rate and lowers adiposity in diet-induced obese mice

PloS one, 2013-07, Vol.8 (7), p.e66923

2013

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Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2

The Journal of clinical investigation, 2006-03, Vol.116 (3), p.817-824

2006

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Fibroblast Growth Factor 19 Increases Metabolic Rate and Reverses Dietary and Leptin-Deficient Diabetes

Endocrinology (Philadelphia), 2004-06, Vol.145 (6), p.2594-2603

2004

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Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice

Hepatology (Baltimore, Md.), 2005-08, Vol.42 (2), p.362-371

2005

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Diacylglycerol acyltranferase 1 anti‐sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis

Hepatology (Baltimore, Md.), 2008-02, Vol.47 (2), p.625-635

2008

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Prevention of Hepatic Steatosis and Hepatic Insulin Resistance by Knockdown of cAMP Response Element-Binding Protein

Cell metabolism, 2009-12, Vol.10 (6), p.499-506

2009

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Reduction of Low Molecular Weight Protein-tyrosine Phosphatase Expression Improves Hyperglycemia and Insulin Sensitivity in Obese Mice

The Journal of biological chemistry, 2007-05, Vol.282 (19), p.14291-14299

2007

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Reduction of JNK1 expression with antisense oligonucleotide improves adiposity in obese mice

American journal of physiology: endocrinology and metabolism, 2008-08, Vol.295 (2), p.E436-E445

2008

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Characterization of novel UCP5/BMCP1 isoforms and differential regulation of UCP4 and UCP5 expression through dietary or temperature manipulation

The FASEB journal, 2000-08, Vol.14 (11), p.1611-1618

2000

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A Protein Phosphatase Methylesterase (PME-1) Is One of Several Novel Proteins Stably Associating with Two Inactive Mutants of Protein Phosphatase 2A

The Journal of biological chemistry, 1999-05, Vol.274 (20), p.14382-14391

1999

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Impact of endotoxin on UCP homolog mRNA abundance, thermoregulation, and mitochondrial proton leak kinetics

American journal of physiology: endocrinology and metabolism, 2000-08, Vol.279 (2), p.E433-E446

2000

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siRNA Inhibition of Lysophosphatidic Acid Receptor 1 (LPAR1) Attenuates Kidney Fibrosis and Improves Kidney Function in a Rat Model of Hypertensive CKD: SA-PO442

Journal of the American Society of Nephrology, 2023-11, Vol.34 (11S), p.845-845

2023

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Targeting Lysophosphatidic Acid Receptor 1 (LPAR1) with siRNA-Lipid Nanoparticles (siRNA-LNP) Is a Potential Therapeutic Approach for CKD -Associated Kidney Fibrosis: SA-PO443

Journal of the American Society of Nephrology, 2023-11, Vol.34 (11S), p.846-846

2023

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Differential induction of peroxisomal beta -oxidation enzymes by clofibric acid and aspirin in piglet tissues

American journal of physiology. Regulatory, integrative and comparative physiology, 2001-11, Vol.281 (5), p.1553-R1561

2001

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Cold elicits the simultaneous induction of fatty acid synthesis and β‐oxidation in murine brown adipose tissue: prediction from differential gene expression and confirmation in vivo

The FASEB journal, 2002-02, Vol.16 (2), p.155-168

2002

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Differential induction of peroxisomal β-oxidation enzymes by clofibric acid and aspirin in piglet tissues

American journal of physiology. Regulatory, integrative and comparative physiology, 2001-11, Vol.50 (5), p.R1553-R1561

2001

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Rates of mitochondrial and peroxisomal β-oxidation of palmitate change during postnatal development and food deprivation in liver, kidney and heart of pigs

The Journal of nutrition, 1997-09, Vol.127 (9), p.1814-1821

1997

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miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

Cell metabolism, 2006-02, Vol.3 (2), p.87-98

2006

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The Role of Peroxisome Proliferator-Activated Receptor γ Coactivator-1 β in the Pathogenesis of Fructose-Induced Insulin Resistance

Cell metabolism, 2009-03, Vol.9 (3), p.252-264

2009

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Food deprivation changes peroxisomal beta-oxidation activity but not catalase activity during postnatal development in pig tissues

The Journal of nutrition, 1998-07, Vol.128 (7), p.1114-1121

1998

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Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice

Hepatology (Baltimore, Md.), 2005-08, Vol.42 (2), p.362-371

2005

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Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis

Peripheral Androgen Receptor Gene Suppression Rescues Disease in Mouse Models of Spinal and Bulbar Muscular Atrophy

Suppression of Diacylglycerol Acyltransferase-2 (DGAT2), but Not DGAT1, with Antisense Oligonucleotides Reverses Diet-induced Hepatic Steatosis and Insulin Resistance

SirT1 knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats

Peripheral reduction of FGFR4 with antisense oligonucleotides increases metabolic rate and lowers adiposity in diet-induced obese mice

Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2

Fibroblast Growth Factor 19 Increases Metabolic Rate and Reverses Dietary and Leptin-Deficient Diabetes

Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice

Diacylglycerol acyltranferase 1 anti‐sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis

Prevention of Hepatic Steatosis and Hepatic Insulin Resistance by Knockdown of cAMP Response Element-Binding Protein

Reduction of Low Molecular Weight Protein-tyrosine Phosphatase Expression Improves Hyperglycemia and Insulin Sensitivity in Obese Mice

Reduction of JNK1 expression with antisense oligonucleotide improves adiposity in obese mice

Characterization of novel UCP5/BMCP1 isoforms and differential regulation of UCP4 and UCP5 expression through dietary or temperature manipulation

A Protein Phosphatase Methylesterase (PME-1) Is One of Several Novel Proteins Stably Associating with Two Inactive Mutants of Protein Phosphatase 2A

Impact of endotoxin on UCP homolog mRNA abundance, thermoregulation, and mitochondrial proton leak kinetics

siRNA Inhibition of Lysophosphatidic Acid Receptor 1 (LPAR1) Attenuates Kidney Fibrosis and Improves Kidney Function in a Rat Model of Hypertensive CKD: SA-PO442

Targeting Lysophosphatidic Acid Receptor 1 (LPAR1) with siRNA-Lipid Nanoparticles (siRNA-LNP) Is a Potential Therapeutic Approach for CKD -Associated Kidney Fibrosis: SA-PO443

Differential induction of peroxisomal beta -oxidation enzymes by clofibric acid and aspirin in piglet tissues

Cold elicits the simultaneous induction of fatty acid synthesis and β‐oxidation in murine brown adipose tissue: prediction from differential gene expression and confirmation in vivo

Differential induction of peroxisomal β-oxidation enzymes by clofibric acid and aspirin in piglet tissues

Rates of mitochondrial and peroxisomal β-oxidation of palmitate change during postnatal development and food deprivation in liver, kidney and heart of pigs

miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting

The Role of Peroxisome Proliferator-Activated Receptor γ Coactivator-1 β in the Pathogenesis of Fructose-Induced Insulin Resistance

Food deprivation changes peroxisomal beta-oxidation activity but not catalase activity during postnatal development in pig tissues

Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice

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