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Predicting In Vivo Efficacy from In Vitro Data: Quantitative Systems Pharmacology Modeling for an Epigenetic Modifier Drug in Cancer

Clinical and translational science, 2020-03, Vol.13 (2), p.419-429

2020

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Relationship between ADAMTS13 activity in clinical remission and the risk of TTP relapse

British journal of haematology, 2008-06, Vol.141 (5), p.651-658

2008

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Treatment of chronic gout. Can we determine when urate stores are depleted enough to prevent attacks of gout?

Journal of rheumatology, 2001-03, Vol.28 (3), p.577

2001

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Physiologically Based Absorption Modeling to Explore the Impact of Food and Gastric pH Changes on the Pharmacokinetics of Alectinib

The AAPS journal, 2016-11, Vol.18 (6), p.1464-1474

2016

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Differences in N-glycan structures found on recombinant IgA1 and IgA2 produced in murine myeloma and CHO cell lines

mAbs, 2010-05, Vol.2 (3), p.320-334

2010

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Impact of Intracranial Artery Disease and Prior Cerebral Infarction on Central Nervous System Complications After Off-Pump Coronary Artery Bypass Grafting

Neurophysiology (New York), 2014-12, Vol.46 (6), p.501-506

2014

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The discovery of potent, selective, and orally bioavailable PDE9 inhibitors as potential hypoglycemic agents

Bioorganic & medicinal chemistry letters, 2009-05, Vol.19 (9), p.2537-2541

2009

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SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation

The Journal of experimental medicine, 2006-06, Vol.203 (6), p.1551-1565

2006

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Establishment of correlation between in vitro enzyme binding potency and in vivo pharmacological activity: application to liver glycogen phosphorylase a inhibitors

The Journal of pharmacology and experimental therapeutics, 2006-06, Vol.317 (3), p.1230

2006

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A survey on osteoporosis management among Filipino general practitioners

Osteoporosis and Sarcopenia, 2017-09, Vol.3 (3), p.S12

2017

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Investigating the effect of autoinduction in cynomolgus monkeys of a novel anticancer MDM2 antagonist, idasanutlin, and relevance to humans

Xenobiotica, 2016-08, Vol.46 (8), p.667-676

2016

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Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles

Drug metabolism and disposition, 1999-06, Vol.27 (6), p.655

1999

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Erratum to: A 10-year follow up of postmenopausal women with osteoporosis for occurrence of osteoporotic fractures

Osteoporosis international, 2010-11, Vol.21 (11), p.1967-1967

2010

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Cysteine Residues Required for the Attachment of the Light Chain in Human IgA2

The Journal of immunology (1950), 2002-11, Vol.169 (9), p.5072-5077

2002

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Uniformity of ionization response of structurally diverse analytes using a chip-based nanoelectrospray ionization source

Rapid communications in mass spectrometry, 2005-01, Vol.19 (21), p.3139-3142

2005

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Cardioprotective effects of ingliforib, a novel glycogen phosphorylase inhibitor

American journal of physiology. Heart and circulatory physiology, 2004-03, Vol.286 (3), p.H1177-H1184

2004

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Potentiation of cytochrome P450/cyclophosphamide-based cancer gene therapy by coexpression of the P450 reductase gene

Cancer research (Chicago, Ill.), 1997-11, Vol.57 (21), p.4830-4837

1997

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In vivo modulation of alternative pathways of P-450-catalyzed cyclophosphamide metabolism: impact on pharmacokinetics and antitumor activity

The Journal of pharmacology and experimental therapeutics, 1999-03, Vol.288 (3), p.928

1999

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Distribution and risk factors of hand, foot, and mouth disease in Changchun, northeastern China

Chinese science bulletin, 2014-02, Vol.59 (5), p.533-538

2014

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Investigation of the Relationship between Type 2 Diabetes and Osteoporosis Using Bayesian Inference

Journal of clinical densitometry, 2007-10, Vol.10 (4), p.386-390

2007

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Identification of a novel glutathione adduct of diclofenac, 4'-hydroxy-2'-glutathion-deschloro-diclofenac, upon incubation with human liver microsomes

Drug metabolism and disposition, 2005-04, Vol.33 (4), p.484

2005

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Effects of Reduced Nocturnal Temperature on Performance and Behavior of Nursery Pigs

Journal of Integrative Agriculture, 2012-09, Vol.11 (9), p.1509-1516

2012

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P450 enzyme expression patterns in the NCI human tumor cell line panel

Drug metabolism and disposition, 2001-03, Vol.29 (3), p.304

2001

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SAP Regulates TH2 Differentiation and PKC-θ-Mediated Activation of NF-κB1

Immunity (Cambridge, Mass.), 2004-11, Vol.21 (5), p.693-706

2004

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Abstract 2796: Predicting in vivo efficacy from in vitro data: Quantitative systems pharmacology modeling for an epigenetic modifier drug in cancer

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2796-2796

2018

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