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Structures of Darunavir-Resistant HIV‑1 Protease Mutant Reveal Atypical Binding of Darunavir to Wide Open Flaps

ACS chemical biology, 2014-06, Vol.9 (6), p.1351-1358

2014

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RhoA mediates cyclooxygenase-2 signaling to disrupt the formation of adherens junctions and increase cell motility

Cancer research (Chicago, Ill.), 2006-12, Vol.66 (24), p.11700-11708

2006

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Innate Immunity SNPs are Associated with Risk for Severe Sepsis after Burn Injury

Clinical medicine & research, 2006-12, Vol.4 (4), p.250-255

2006

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Potent Antiviral HIV-1 Protease Inhibitor GRL-02031 Adapts to the Structures of Drug Resistant Mutants with Its P1′-Pyrrolidinone Ring

Journal of medicinal chemistry, 2012-04, Vol.55 (7), p.3387-3397

2012

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Functional PAK-2 knockout and replacement with a caspase cleavage-deficient mutant in mice reveals differential requirements of full-length PAK-2 and caspase-activated PAK-2p34

Mammalian genome, 2011-06, Vol.22 (5-6), p.306-317

2011

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Elevated p21-Activated Kinase 2 Activity Results in Anchorage-Independent Growth and Resistance to Anticancer Drug–Induced Cell Death

Neoplasia (New York, N.Y.), 2009-03, Vol.11 (3), p.286-297

2009

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Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease

Movement disorders, 2015-06, Vol.30 (7), p.936-944

2015

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Differential regulation of cyclooxygenase 2 expression by small GTPases Ras, Rac1, and RhoA

Journal of cellular biochemistry, 2005-10, Vol.96 (2), p.314-329

2005

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Epistatic Interactions are Critical to Gene-Association Studies : PAI-1 and Risk for Mortality After Burn Injury

Journal of burn care & research, 2008, Vol.29 (1), p.168-175

2008

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Caspase Activation of p21-Activated Kinase 2 Occurs During Cisplatin-Induced Apoptosis of SH-SY5Y Neuroblastoma Cells and in SH-SY5Y Cell Culture Models of Alzheimer's and Parkinson's Disease

Japanese clinical medicine, 2010-04, Vol.2010 (3), p.23

2010

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Targeting RhoA/Rho kinase and p21-activated kinase signaling to prevent cancer development and progression

Recent patents on anti-cancer drug discovery, 2009-06, Vol.4 (2), p.110-124

2009

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Molecular or pharmacologic inhibition of the CD14 signaling pathway protects against burn-related myocardial inflammation and dysfunction

Shock (Augusta, Ga.), 2008-12, Vol.30 (6), p.705-713

2008

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CD14-159 C allele is associated with increased risk of mortality after burn injury

Shock (Augusta, Ga.), 2007-03, Vol.27 (3), p.232-237

2007

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Cyclooxygenase-2 Expression Inhibits Trophic Withdrawal Apoptosis in Nerve Growth Factor-differentiated PC12 Cells

The Journal of biological chemistry, 2000-04, Vol.275 (16), p.12095-12101

2000

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Genetic variation within APP processing genes correlates with cerebrospinal fluid APP cleavage product levels in Alzheimer patients and cognitively normal subjects

Alzheimer's & dementia, 2010-07, Vol.6 (4), p.S189-S190

2010

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Cone visual pigments of the Australian marsupials, the stripe-faced and fat-tailed dunnarts: Sequence and inferred spectral properties

Visual neuroscience, 2004-05, Vol.21 (3), p.223-229

2004

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CTDSP1 inhibitor rabeprazole regulates DNA-PKcs dependent topoisomerase I degradation and irinotecan drug resistance in colorectal cancer

PloS one, 2020-08, Vol.15 (8), p.e0228002-e0228002

2020

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Cyclooxygenase 2 Promotes Cell Survival by Stimulation of Dynein Light Chain Expression and Inhibition of Neuronal Nitric Oxide Synthase Activity

Molecular and Cellular Biology, 2000-11, Vol.20 (22), p.8571-8579

2000

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Cerebrospinal fluid A beta sub(42) levels and APP processing pathway genes in Parkinson's disease

Movement disorders, 2015-06, Vol.30 (7), p.936-944

2015

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Cerebrospinal fluid A[beta]42 levels and APP processing pathway genes in Parkinson's disease

Movement disorders, 2015-06, Vol.30 (7), p.936

2015

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Cerebrospinal fluid Aβ 42 levels and APP processing pathway genes in Parkinson's disease

Movement disorders, 2015-06, Vol.30 (7), p.936-944

2015

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Cyclooxygenase 2 inhibits SAPK activation in neuronal apoptosis

Biochemical and biophysical research communications, 2003-01, Vol.300 (4), p.884-888

2003

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Apolipoprotein E genotypes in Parkinson's disease with and without dementia

Annals of neurology, 1995-02, Vol.37 (2), p.242-245

1995

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Potent Antiviral HIV-1 Protease Inhibitor GRL-02031 Adapts to the Structures of Drug Resistant Mutants with Its P1;#8242;-Pyrrolidinone Ring

Journal of medicinal chemistry, 2012-11, Vol.55 ((7) ; 04, 2012)

2012

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Establishment of a novel cell-based assay for screening small molecule antagonists of human interleukin-6 receptor

Acta pharmacologica Sinica, 2014-11, Vol.35 (11), p.1453-1462

2014

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Structures of Darunavir-Resistant HIV‑1 Protease Mutant Reveal Atypical Binding of Darunavir to Wide Open Flaps

RhoA mediates cyclooxygenase-2 signaling to disrupt the formation of adherens junctions and increase cell motility

Innate Immunity SNPs are Associated with Risk for Severe Sepsis after Burn Injury

Potent Antiviral HIV-1 Protease Inhibitor GRL-02031 Adapts to the Structures of Drug Resistant Mutants with Its P1′-Pyrrolidinone Ring

Functional PAK-2 knockout and replacement with a caspase cleavage-deficient mutant in mice reveals differential requirements of full-length PAK-2 and caspase-activated PAK-2p34

Elevated p21-Activated Kinase 2 Activity Results in Anchorage-Independent Growth and Resistance to Anticancer Drug–Induced Cell Death

Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease

Differential regulation of cyclooxygenase 2 expression by small GTPases Ras, Rac1, and RhoA

Epistatic Interactions are Critical to Gene-Association Studies : PAI-1 and Risk for Mortality After Burn Injury

Caspase Activation of p21-Activated Kinase 2 Occurs During Cisplatin-Induced Apoptosis of SH-SY5Y Neuroblastoma Cells and in SH-SY5Y Cell Culture Models of Alzheimer's and Parkinson's Disease

Targeting RhoA/Rho kinase and p21-activated kinase signaling to prevent cancer development and progression

Molecular or pharmacologic inhibition of the CD14 signaling pathway protects against burn-related myocardial inflammation and dysfunction

CD14-159 C allele is associated with increased risk of mortality after burn injury

Cyclooxygenase-2 Expression Inhibits Trophic Withdrawal Apoptosis in Nerve Growth Factor-differentiated PC12 Cells

Genetic variation within APP processing genes correlates with cerebrospinal fluid APP cleavage product levels in Alzheimer patients and cognitively normal subjects

Cone visual pigments of the Australian marsupials, the stripe-faced and fat-tailed dunnarts: Sequence and inferred spectral properties

CTDSP1 inhibitor rabeprazole regulates DNA-PKcs dependent topoisomerase I degradation and irinotecan drug resistance in colorectal cancer

Cyclooxygenase 2 Promotes Cell Survival by Stimulation of Dynein Light Chain Expression and Inhibition of Neuronal Nitric Oxide Synthase Activity

Cerebrospinal fluid A beta sub(42) levels and APP processing pathway genes in Parkinson's disease

Cerebrospinal fluid A[beta]42 levels and APP processing pathway genes in Parkinson's disease

Cerebrospinal fluid Aβ 42 levels and APP processing pathway genes in Parkinson's disease

Cyclooxygenase 2 inhibits SAPK activation in neuronal apoptosis

Apolipoprotein E genotypes in Parkinson's disease with and without dementia

Potent Antiviral HIV-1 Protease Inhibitor GRL-02031 Adapts to the Structures of Drug Resistant Mutants with Its P1;#8242;-Pyrrolidinone Ring

Establishment of a novel cell-based assay for screening small molecule antagonists of human interleukin-6 receptor

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