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Design, synthesis, anti-inflammatory evaluation, and molecular modelling of new coumarin-based analogs combined curcumin and other heterocycles as potential TNF-α production inhibitors via upregulating Nrf2/HO-1, downregulating AKT/mTOR signalling pathways and downregulating NF-κB in LPS induced macrophages

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2243551-2243551

2023

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The protective effect of biochanin A against rotenone-induced neurotoxicity in mice involves enhancing of PI3K/Akt/mTOR signaling and beclin-1 production

Ecotoxicology and environmental safety, 2020-12, Vol.205, p.111344-111344, Article 111344

2020

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Protective effect of metformin on rat diabetic retinopathy involves suppression of toll-like receptor 4/nuclear factor-k B expression and glutamate excitotoxicity

International immunopharmacology, 2021-01, Vol.90, p.107193, Article 107193

2021

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Synthesis and Antitumor Activity of Doxycycline Polymeric Nanoparticles: Effect on Tumor Apoptosis in Solid Ehrlich Carcinoma

Molecules (Basel, Switzerland), 2020-07, Vol.25 (14), p.3230

2020

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Carbamazepine Alleviates Retinal and Optic Nerve Neural Degeneration in Diabetic Mice via Nerve Growth Factor-Induced PI3K/Akt/mTOR Activation

Frontiers in neuroscience, 2019-11, Vol.13, p.1089

2019

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Anti-inflammatory drug approach: Synthesis and biological evaluation of novel pyrazolo[3,4-d]pyrimidine compounds

Bioorganic chemistry, 2019-05, Vol.86, p.393-400

2019

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Synthesis of new quaternized chitosan Schiff bases and their N-alkyl derivatives as antimicrobial and anti-biofilm retardants in membrane technology

International journal of biological macromolecules, 2024-05, Vol.267 (Pt 2), p.131635-131635, Article 131635

2024

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Evening Primrose Oil Ameliorates Hyperleptinemia and Reproductive Hormone Disturbances in Obese Female Rats: Impact on Estrus Cyclicity

Frontiers in endocrinology (Lausanne), 2020-01, Vol.10, p.942-942

2020

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Synthesis and Cytotoxicity Against Human Breast Carcinoma Cell Evaluation of Some New 3,4-Disubstituted Coumarin Derivatives

Pharmaceutical chemistry journal, 2022, Vol.55 (10), p.1040-1049

2022

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Synthesis and anticancer activity of novel benzimidazole and benzothiazole derivatives against HepG2 liver cancer cells

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2012-03, Vol.8 (2), p.151-162

2012

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Corrigendum to “Inhibitory effect of valproate sodium on pain behavior in diabetic mice involves suppression of spinal histone deacetylase 1 and inflammatory mediators” [Int. Immunopharmacol. 70 (2019) 16–27]

International immunopharmacology, 2023-04, Vol.117, p.109807-109807, Article 109807

2023

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Design, synthesis and biological screening of some pyridinylpyrazole and pyridinylisoxazole derivatives as potential anti-inflammatory, analgesic, antipyretic and antimicrobial agents

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2014-05, Vol.10 (3), p.318-338

2014

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Inhibitory effect of valproate sodium on pain behavior in diabetic mice involves suppression of spinal histone deacetylase 1 and inflammatory mediators

International immunopharmacology, 2019-05, Vol.70, p.16-27

2019

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Effects of Quercetin and Coenzyme Q10 on Biochemical, Molecular, and Morphological Parameters of Skeletal Muscle in Trained Diabetic Rats

Current molecular pharmacology, 2022-01, Vol.15 (1), p.239-251

2022

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Design, synthesis and antimicrobial evaluation of methyl pyridyl-2,4- dioxobutanoates and some new derived ring systems

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2015-01, Vol.11 (4), p.407-414

2015

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Pyrazole compound 2-MBAPA as a novel inhibitor of microglial activation and neurotoxicity in vitro and in vivo

Journal of Alzheimer's disease, 2011-01, Vol.27 (3), p.531-541

2011

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Methanolic extracts of a selected Egyptian Vicia faba cultivar mitigate the oxidative/inflammatory burden and afford neuroprotection in a mouse model of Parkinson’s disease

Inflammopharmacology, 2021-02, Vol.29 (1), p.221-235

2021

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Synthesis and biological evaluation of novel pyrazolyl-2,4-thiazolidinediones as anti-inflammatory and neuroprotective agents

Bioorganic & medicinal chemistry, 2010-03, Vol.18 (5), p.2019-2028

2010

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Chemopreventive effect of α-hederin/carboplatin combination against experimental colon hyperplasia and impact on JNK signaling

Toxicology mechanisms and methods, 2021-02, Vol.31 (2), p.138-149

2021

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Correction to: Methanolic extracts of a selected Egyptian Vicia faba cultivar mitigate the oxidative/inflammatory burden and afford neuroprotection in a mouse model of Parkinson's disease

Inflammopharmacology, 2022-04, Vol.30 (2), p.683-683

2022

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Novel quinuclidinone derivatives induced apoptosis in human breast cancer via targeting p53

Bioorganic chemistry, 2017-06, Vol.72, p.57-63

2017

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Novel thiosemicarbazides induced apoptosis in human MCF-7 breast cancer cells via JNK signaling

Journal of enzyme inhibition and medicinal chemistry, 2015-09, Vol.30 (5), p.786-795

2015

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Design, Synthesis, and Anti-Breast Cancer Activity of Some Hybrid Molecules Containing Coumarin Moiety

Russian journal of bioorganic chemistry, 2021, Vol.47 (1), p.149-157

2021

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Synthesis and biological evaluation of novel pyrazole compounds

Bioorganic & medicinal chemistry, 2010-08, Vol.18 (15), p.5685-5696

2010

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GC-MS investigation and toxicological evaluation of alkaloids from Leptadenia pyrotechnica

Pharmaceutical biology, 2009-10, Vol.47 (10), p.994-1003

2009

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The protective effect of biochanin A against rotenone-induced neurotoxicity in mice involves enhancing of PI3K/Akt/mTOR signaling and beclin-1 production

Protective effect of metformin on rat diabetic retinopathy involves suppression of toll-like receptor 4/nuclear factor-k B expression and glutamate excitotoxicity

Synthesis and Antitumor Activity of Doxycycline Polymeric Nanoparticles: Effect on Tumor Apoptosis in Solid Ehrlich Carcinoma

Carbamazepine Alleviates Retinal and Optic Nerve Neural Degeneration in Diabetic Mice via Nerve Growth Factor-Induced PI3K/Akt/mTOR Activation

Anti-inflammatory drug approach: Synthesis and biological evaluation of novel pyrazolo[3,4-d]pyrimidine compounds

Synthesis of new quaternized chitosan Schiff bases and their N-alkyl derivatives as antimicrobial and anti-biofilm retardants in membrane technology

Evening Primrose Oil Ameliorates Hyperleptinemia and Reproductive Hormone Disturbances in Obese Female Rats: Impact on Estrus Cyclicity

Synthesis and Cytotoxicity Against Human Breast Carcinoma Cell Evaluation of Some New 3,4-Disubstituted Coumarin Derivatives

Synthesis and anticancer activity of novel benzimidazole and benzothiazole derivatives against HepG2 liver cancer cells

Corrigendum to “Inhibitory effect of valproate sodium on pain behavior in diabetic mice involves suppression of spinal histone deacetylase 1 and inflammatory mediators” [Int. Immunopharmacol. 70 (2019) 16–27]

Design, synthesis and biological screening of some pyridinylpyrazole and pyridinylisoxazole derivatives as potential anti-inflammatory, analgesic, antipyretic and antimicrobial agents

Inhibitory effect of valproate sodium on pain behavior in diabetic mice involves suppression of spinal histone deacetylase 1 and inflammatory mediators

Effects of Quercetin and Coenzyme Q10 on Biochemical, Molecular, and Morphological Parameters of Skeletal Muscle in Trained Diabetic Rats

Design, synthesis and antimicrobial evaluation of methyl pyridyl-2,4- dioxobutanoates and some new derived ring systems

Pyrazole compound 2-MBAPA as a novel inhibitor of microglial activation and neurotoxicity in vitro and in vivo

Methanolic extracts of a selected Egyptian Vicia faba cultivar mitigate the oxidative/inflammatory burden and afford neuroprotection in a mouse model of Parkinson’s disease

Synthesis and biological evaluation of novel pyrazolyl-2,4-thiazolidinediones as anti-inflammatory and neuroprotective agents

Chemopreventive effect of α-hederin/carboplatin combination against experimental colon hyperplasia and impact on JNK signaling

Correction to: Methanolic extracts of a selected Egyptian Vicia faba cultivar mitigate the oxidative/inflammatory burden and afford neuroprotection in a mouse model of Parkinson's disease

Novel quinuclidinone derivatives induced apoptosis in human breast cancer via targeting p53

Novel thiosemicarbazides induced apoptosis in human MCF-7 breast cancer cells via JNK signaling

Design, Synthesis, and Anti-Breast Cancer Activity of Some Hybrid Molecules Containing Coumarin Moiety

Synthesis and biological evaluation of novel pyrazole compounds

GC-MS investigation and toxicological evaluation of alkaloids from Leptadenia pyrotechnica

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