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Hybrid Inhibitors of Phosphatidylinositol 3-Kinase (PI3K) and the Mammalian Target of Rapamycin (mTOR): Design, Synthesis, and Superior Antitumor Activity of Novel Wortmannin−Rapamycin Conjugates

Journal of medicinal chemistry, 2010-01, Vol.53 (1), p.452-459

2010

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Tigecycline MIC Testing by Broth Dilution Requires Use of Fresh Medium or Addition of the Biocatalytic Oxygen-Reducing Reagent Oxyrase To Standardize the Test Method

Antimicrobial Agents and Chemotherapy, 2005-09, Vol.49 (9), p.3903-3909

2005

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Optimization of 4-Phenylamino-3-quinolinecarbonitriles as Potent Inhibitors of Src Kinase Activity

Journal of medicinal chemistry, 2001-11, Vol.44 (23), p.3965-3977

2001

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Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery-Building chiral technology toolboxes

Chirality (New York, N.Y.), 2007-09, Vol.19 (9), p.658-682

2007

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In Vivo Efficacy and Pharmacokinetics of AC98-6446, a Novel Cyclic Glycopeptide, in Experimental Infection Models

Antimicrobial Agents and Chemotherapy, 2004-05, Vol.48 (5), p.1708-1712

2004

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Rapid Cloning and Heterologous Expression of the Meridamycin Biosynthetic Gene Cluster Using a Versatile Escherichia coli−Streptomyces Artificial Chromosome Vector, pSBAC

Journal of natural products (Washington, D.C.), 2009-03, Vol.72 (3), p.389-395

2009

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Integrity profiling of high throughput screening hits using LC-MS and related techniques

Combinatorial chemistry & high throughput screening, 2005-09, Vol.8 (6), p.459-466

2005

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Synthesis and Structure–Activity Relationships of Ring-Opened 17-Hydroxywortmannins: Potent Phosphoinositide 3-Kinase Inhibitors with Improved Properties and Anticancer Efficacy

Journal of medicinal chemistry, 2008-03, Vol.51 (5), p.1319-1323

2008

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A Cell Wall-Active Lipopeptide from the Fungus Pochonia bulbillosa

Journal of natural products (Washington, D.C.), 2008-12, Vol.71 (12), p.2045-2048

2008

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First Scale-Up: Problems and Resolutions on the Synthesis of WAY-253752, a Novel, Dual-Acting SSRI/5HT1A Antagonist

Organic process research & development, 2008-01, Vol.12 (1), p.76-80

2008

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First Scale-Up: Problems and Resolutions on the Synthesis of WAY-253752, a Novel, Dual-Acting SSRI/5HT 1A Antagonist

Organic process research & development, 2008-01, Vol.12 (1), p.76-80

2008

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A Role for WDR5 in Integrating Threonine 11 Phosphorylation to Lysine 4 Methylation on Histone H3 during Androgen Signaling and in Prostate Cancer

Molecular cell, 2014-05, Vol.54 (4), p.613-625

2014

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Maternal and perinatal outcomes of prolonged second stage of labour: a historical cohort study of over 51,000 women

BMC pregnancy and childbirth, 2023-06, Vol.23 (1), p.467-467, Article 467

2023

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Designing Group Assignments to Develop Groupwork Skills

Journal of information systems education, 2021-09, Vol.32 (4), p.274-282

2021

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Sodium Bicarbonate for Metabolic Acidosis in the ICU: Results of a Pilot Randomized Double-Blind Clinical Trial

Critical care medicine, 2023-11, Vol.51 (11), p.e221-e233

2023

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Development of a pilot interprofessional education workshop for healthcare students and assessment of interprofessional collaborative competency attainment

Journal of interprofessional care, 2023-11, Vol.ahead-of-print (ahead-of-print), p.1-10

2023

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A Role for WDR5 in Integrating Threonine 11 Phosphorylation to Lysine 4 Methylation on Histone H3 during Androgen Signaling and in Prostate Cancer

Molecular cell, 2015-05, Vol.58 (3), p.557-557

2015

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Vitamin D status as an international issue: National surveys and the problem of standardization

Scandinavian journal of clinical & laboratory investigation. Supplement, 2012-04, Vol.72 (S243), p.32-40

2012

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Baseline Assessment of 25-Hydroxyvitamin D Assay Performance: A Vitamin D Standardization Program (VDSP) Interlaboratory Comparison Study

Journal of AOAC International, 2017-09, Vol.100 (5), p.1244-1252

2017

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Baseline Assessment of 25-Hydroxyvitamin D Reference Material and Proficiency Testing/External Quality Assurance Material Commutability: A Vitamin D Standardization Program Study

Journal of AOAC International, 2017-09, Vol.100 (5), p.1288-1293

2017

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Evaluation of international recruitment of health professionals in England

Journal of health services research & policy, 2010-10, Vol.15 (4), p.195-203

2010

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Stakeholder engagement for regional geoscientific surveying: the Tellus Border communications campaign

Unearthed, 2016

Young, Mike

2016

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The Tellus geochemical surveys, results and applications

Unearthed, 2016

Young, Mike

2016

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Hybrid Inhibitors of Phosphatidylinositol 3-Kinase (PI3K) and the Mammalian Target of Rapamycin (mTOR): Design, Synthesis, and Superior Antitumor Activity of Novel Wortmannin−Rapamycin Conjugates

Tigecycline MIC Testing by Broth Dilution Requires Use of Fresh Medium or Addition of the Biocatalytic Oxygen-Reducing Reagent Oxyrase To Standardize the Test Method

Optimization of 4-Phenylamino-3-quinolinecarbonitriles as Potent Inhibitors of Src Kinase Activity

Enantiomeric separation and determination of absolute stereochemistry of asymmetric molecules in drug discovery-Building chiral technology toolboxes

In Vivo Efficacy and Pharmacokinetics of AC98-6446, a Novel Cyclic Glycopeptide, in Experimental Infection Models

Rapid Cloning and Heterologous Expression of the Meridamycin Biosynthetic Gene Cluster Using a Versatile Escherichia coli−Streptomyces Artificial Chromosome Vector, pSBAC

Integrity profiling of high throughput screening hits using LC-MS and related techniques

Synthesis and Structure–Activity Relationships of Ring-Opened 17-Hydroxywortmannins: Potent Phosphoinositide 3-Kinase Inhibitors with Improved Properties and Anticancer Efficacy

A Cell Wall-Active Lipopeptide from the Fungus Pochonia bulbillosa

First Scale-Up: Problems and Resolutions on the Synthesis of WAY-253752, a Novel, Dual-Acting SSRI/5HT1A Antagonist

First Scale-Up: Problems and Resolutions on the Synthesis of WAY-253752, a Novel, Dual-Acting SSRI/5HT 1A Antagonist

A Role for WDR5 in Integrating Threonine 11 Phosphorylation to Lysine 4 Methylation on Histone H3 during Androgen Signaling and in Prostate Cancer

Maternal and perinatal outcomes of prolonged second stage of labour: a historical cohort study of over 51,000 women

Designing Group Assignments to Develop Groupwork Skills

Sodium Bicarbonate for Metabolic Acidosis in the ICU: Results of a Pilot Randomized Double-Blind Clinical Trial

Development of a pilot interprofessional education workshop for healthcare students and assessment of interprofessional collaborative competency attainment

A Role for WDR5 in Integrating Threonine 11 Phosphorylation to Lysine 4 Methylation on Histone H3 during Androgen Signaling and in Prostate Cancer

Vitamin D status as an international issue: National surveys and the problem of standardization

Baseline Assessment of 25-Hydroxyvitamin D Assay Performance: A Vitamin D Standardization Program (VDSP) Interlaboratory Comparison Study

Baseline Assessment of 25-Hydroxyvitamin D Reference Material and Proficiency Testing/External Quality Assurance Material Commutability: A Vitamin D Standardization Program Study

Impact of the COVID-19 pandemic on cancer care in Ireland – Perspectives from a COVID-19 and Cancer Working Group

Evaluation of international recruitment of health professionals in England

Stakeholder engagement for regional geoscientific surveying: the Tellus Border communications campaign

The Tellus geochemical surveys, results and applications

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