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HCN2 Ion Channels Play a Central Role in Inflammatory and Neuropathic Pain

Science (American Association for the Advancement of Science), 2011-09, Vol.333 (6048), p.1462-1466

2011

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Inflammatory and neuropathic pain are rapidly suppressed by peripheral block of hyperpolarisation-activated cyclic nucleotide-gated ion channels

Pain (Amsterdam), 2014-09, Vol.155 (9), p.1708

2014

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Potentiation of α7 nicotinic acetylcholine receptors via an allosteric transmembrane site

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (38), p.14686-14691

2008

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Functional confirmation that the R1488 variant in SCN9A results in complete loss-of-function of Nav1.7

BMC medical genetics, 2018-07, Vol.19 (1), p.124-124, Article 124

2018

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Agonist activation of alpha 7 nicotinic acetylcholine receptors via an allosteric transmembrane site

Proceedings of the National Academy of Sciences - PNAS, 2011-04, Vol.108 (14), p.5867-5872

2011

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Potentiation of alpha 7 nicotinic acetylcholine receptors via an allosteric transmembrane site

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (38), p.14686-14691

2008

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Competitive binding at a nicotinic receptor transmembrane site of two α7-selective positive allosteric modulators with differing effects on agonist-evoked desensitization

Neuropharmacology, 2011-12, Vol.61 (8), p.1306-1313

2011

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Agonist activation of α7 nicotinic acetylcholine receptors via an allosteric transmembrane site

Proceedings of the National Academy of Sciences - PNAS, 2011-04, Vol.108 (14), p.5867-5872

2011

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Characterizing Human Stem Cell–derived Sensory Neurons at the Single-cell Level Reveals Their Ion Channel Expression and Utility in Pain Research

Molecular therapy, 2014-08, Vol.22 (8), p.1530-1543

2014

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An Intracellular Allosteric Modulator Binding Pocket in SK2 Ion Channels Is Shared by Multiple Chemotypes

Structure (London), 2018-04, Vol.26 (4), p.533-544.e3

2018

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A Comprehensive Functional Analysis of NTRK1 Missense Mutations Causing Hereditary Sensory and Autonomic Neuropathy Type IV (HSAN IV)

Human mutation, 2017-01, Vol.38 (1), p.55-63

2017

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Functional confirmation that the R1488 variant in SCN9A results in complete loss-of-function of Na v 1.7

BMC medical genetics, 2018-07, Vol.19 (1), p.124

2018

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Species Selectivity of a Nicotinic Acetylcholine Receptor Agonist Is Conferred by Two Adjacent Extracellular beta 4 Amino Acids that Are Implicated in the Coupling of Binding to Channel Gating

Molecular pharmacology, 2007-02, Vol.71 (2), p.389-397

2007

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HCN2 ion channels: an emerging role as the pacemakers of pain

Trends in pharmacological sciences (Regular ed.), 2012-08, Vol.33 (8), p.456-463

2012

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Transcriptional regulator PRDM12 is essential for human pain perception

Nature genetics, 2015-07, Vol.47 (7), p.803-808

2015

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Dialetheism and its Applications

1st ed. 2019., 2020

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Competitive binding at a nicotinic receptor transmembrane site of two ?7-selective positive allosteric modulators with differing effects on agonist-evoked desensitization

Neuropharmacology, 2011-12, Vol.61 (8), p.1306-1313

2011

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Characterization of type I and type II positive allosteric modulators of α7 nicotinic acetylcholine receptors

Biochemical pharmacology, 2009-10, Vol.78 (7), p.914-914

2009

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Species Selectivity of a Nicotinic Acetylcholine Receptor Agonist Is Conferred by Two Adjacent Extracellular β4 Amino Acids that Are Implicated in the Coupling of Binding to Channel Gating

Molecular pharmacology, 2007-02, Vol.71 (2), p.389-397

2007

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Agonist activation of [alpha]7 nicotinic acetylcholine receptors via an allosteric transmembrane site

Proceedings of the National Academy of Sciences - PNAS, 2011-04, Vol.108 (14), p.5867

2011

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Characterizing Human Stem Cell-derived Sensory Neurons at the Single-cell Level Reveals Their Ion Channel Expression and Utility in Pain Research super(MT)Open

Molecular therapy, 2014-08, Vol.22 (8), p.1530-1543

2014

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Agonist activation of Î±7 nicotinic acetylcholine receptors via an allosteric transmembrane site

Proceedings of the National Academy of Sciences - PNAS, 2011, Vol.108 (14), p.5867-5872

2011

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Erratum: Corrigendum: Transcriptional regulator PRDM12 is essential for human pain perception

Nature genetics, 2015-07, Vol.47 (8), p.962-962

2015

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Corrigendum: Transcriptional regulator PRDM12 is essential for human pain perception

Nature genetics, 2015-08, Vol.47 (8), p.962-962

2015

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Potentiation of [alpha]7 nicotinic acetyicholine receptors via an allosteric transmembrane site

Proceedings of the National Academy of Sciences - PNAS, 2008-09, Vol.105 (38), p.14686

2008

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HCN2 Ion Channels Play a Central Role in Inflammatory and Neuropathic Pain

Inflammatory and neuropathic pain are rapidly suppressed by peripheral block of hyperpolarisation-activated cyclic nucleotide-gated ion channels

Potentiation of α7 nicotinic acetylcholine receptors via an allosteric transmembrane site

Functional confirmation that the R1488 variant in SCN9A results in complete loss-of-function of Nav1.7

Agonist activation of alpha 7 nicotinic acetylcholine receptors via an allosteric transmembrane site

Potentiation of alpha 7 nicotinic acetylcholine receptors via an allosteric transmembrane site

Competitive binding at a nicotinic receptor transmembrane site of two α7-selective positive allosteric modulators with differing effects on agonist-evoked desensitization

Agonist activation of α7 nicotinic acetylcholine receptors via an allosteric transmembrane site

Characterizing Human Stem Cell–derived Sensory Neurons at the Single-cell Level Reveals Their Ion Channel Expression and Utility in Pain Research

An Intracellular Allosteric Modulator Binding Pocket in SK2 Ion Channels Is Shared by Multiple Chemotypes

A Comprehensive Functional Analysis of NTRK1 Missense Mutations Causing Hereditary Sensory and Autonomic Neuropathy Type IV (HSAN IV)

Functional confirmation that the R1488 variant in SCN9A results in complete loss-of-function of Na v 1.7

Species Selectivity of a Nicotinic Acetylcholine Receptor Agonist Is Conferred by Two Adjacent Extracellular beta 4 Amino Acids that Are Implicated in the Coupling of Binding to Channel Gating

HCN2 ion channels: an emerging role as the pacemakers of pain

Transcriptional regulator PRDM12 is essential for human pain perception

Dialetheism and its Applications

Competitive binding at a nicotinic receptor transmembrane site of two ?7-selective positive allosteric modulators with differing effects on agonist-evoked desensitization

Characterization of type I and type II positive allosteric modulators of α7 nicotinic acetylcholine receptors

Species Selectivity of a Nicotinic Acetylcholine Receptor Agonist Is Conferred by Two Adjacent Extracellular β4 Amino Acids that Are Implicated in the Coupling of Binding to Channel Gating

Agonist activation of [alpha]7 nicotinic acetylcholine receptors via an allosteric transmembrane site

Characterizing Human Stem Cell-derived Sensory Neurons at the Single-cell Level Reveals Their Ion Channel Expression and Utility in Pain Research super(MT)Open

Agonist activation of Î±7 nicotinic acetylcholine receptors via an allosteric transmembrane site

Erratum: Corrigendum: Transcriptional regulator PRDM12 is essential for human pain perception

Corrigendum: Transcriptional regulator PRDM12 is essential for human pain perception

Potentiation of [alpha]7 nicotinic acetyicholine receptors via an allosteric transmembrane site

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