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Will the Real Single HCN Channel Please Stand Up?

Biophysical journal, 2013-10, Vol.105 (7), p.1549-1550

Young, Edgar C.

2013

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Structural basis for modulation and agonist specificity of HCN pacemaker channels

Nature, 2003-09, Vol.425 (6954), p.200-205

2003

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HCN Channel C-Terminal Region Speeds Activation Rates Independently of Autoinhibition

The Journal of membrane biology, 2015-12, Vol.248 (6), p.1043-1060

2015

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Cytoplasmic cAMP-sensing domain of hyperpolarization-activated cation (HCN) channels uses two structurally distinct mechanisms to regulate voltage gating

Proceedings of the National Academy of Sciences - PNAS, 2011-01, Vol.108 (2), p.609-614

2011

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Cytoplasmic Autoinhibition in HCN Channels is Regulated by the Transmembrane Region

The Journal of membrane biology, 2020-04, Vol.253 (2), p.153-166

2020

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Distinct Structural Determinants of Efficacy and Sensitivity in the Ligand-binding Domain of Cyclic Nucleotide-gated Channels

The Journal of biological chemistry, 2004-01, Vol.279 (5), p.3553-3562

2004

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Bimodal agonism in heteromeric cyclic nucleotide-gated channels

Channels (Austin, Tex.), 2009-11, Vol.3 (6), p.427-436

2009

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Coupling of kinesin steps to ATP hydrolysis

Nature (London), 1997-07, Vol.388 (6640), p.390-393

1997

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Dispersion of Silver Nanoparticles into Polymer Matrix Dry Adhesives to Achieve Antibacterial Properties, Increased Adhesion, and Optical Absorption

Macromolecular reaction engineering, 2013-11, Vol.7 (11), p.624-631

2013

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A Conserved Tripeptide in CNG and HCN Channels Regulates Ligand Gating by Controlling C-Terminal Oligomerization

Neuron (Cambridge, Mass.), 2004-12, Vol.44 (5), p.823-834

2004

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Ligand-binding domain subregions contributing to bimodal agonism in cyclic nucleotide-gated channels

The Journal of general physiology, 2011-06, Vol.137 (6), p.591-603

2011

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Sensitivity of HCN channel deactivation to cAMP is amplified by an S4 mutation combined with activation mode shift

Pflügers Archiv, 2009-09, Vol.458 (5), p.877-889

2009

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Does Bimodal Agonism in Cyclic Nucleotide-Gated (CNG) Channels Preserve the Classical Binding Site and Pore Structure?

Biophysical journal, 2016-02, Vol.110 (3), p.292a-292a

2016

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A Charged Residue in the HCN Channel C-Linker Stabilizes the Open State

Biophysical journal, 2016-02, Vol.110 (3), p.282a-282a

2016

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A single residue exerts two contrasting effects on autoinhibition of HCN channels

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Failure of a single-headed kinesin to track parallel to microtubule protofilaments

Nature (London), 1995-02, Vol.373 (6516), p.718-721

1995

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HCN C-Terminal Region Speeds Activation Independently of Autoinhibition

Biophysical journal, 2014-01, Vol.106 (2), p.155a-155a

2014

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Role of Interactions between Transmembrane and C-Terminal Regions in Voltage-Dependent Activation of HCN4 Channels

Biophysical journal, 2018-02, Vol.114 (3), p.120a-121a

2018

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C-Linker of cyclic nucleotide-gated channels controls coupling of ligand binding to channel gating

The Journal of general physiology, 1999-01, Vol.113 (1), p.17-34

1999

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Fluorescence Investigations of the Rate‐Limiting Step in the HCN Ion Channel Deactivation Pathway

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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One-Headed Kinesin Derivatives Move by a Nonprocessive, Low-Duty Ratio Mechanism Unlike That of Two-Headed Kinesin

Biochemistry (Easton), 1998-03, Vol.37 (10), p.3467-3479

1998

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Efficient coupling of ligand binding to channel opening by the binding domain of a modulatory (beta) subunit of the olfactory cyclic nucleotide-gated channel

The Journal of general physiology, 2001-11, Vol.118 (5), p.523-546

2001

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Rapid Deactivation of An HCN Channel Indicates a New Mechanism Using the Cyclic AMP-Sensing Domain, Different From Autoinhibition and Open State Trapping

Biophysical journal, 2011-02, Vol.100 (3), p.103a-103a

2011

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Modulation of HCN Channel Deactivation Kinetics by CAMP and Depolarization Can Be Amplified by Mode Shift

Biophysical journal, 2009-02, Vol.96 (3), p.484a-485a

2009

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Subunit Interactions in Dimeric Kinesin Heavy Chain Derivatives That Lack the Kinesin Rod

The Journal of biological chemistry, 1995-02, Vol.270 (8), p.3926-3931

1995

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Will the Real Single HCN Channel Please Stand Up?

Structural basis for modulation and agonist specificity of HCN pacemaker channels

HCN Channel C-Terminal Region Speeds Activation Rates Independently of Autoinhibition

Cytoplasmic cAMP-sensing domain of hyperpolarization-activated cation (HCN) channels uses two structurally distinct mechanisms to regulate voltage gating

Cytoplasmic Autoinhibition in HCN Channels is Regulated by the Transmembrane Region

Distinct Structural Determinants of Efficacy and Sensitivity in the Ligand-binding Domain of Cyclic Nucleotide-gated Channels

Bimodal agonism in heteromeric cyclic nucleotide-gated channels

Coupling of kinesin steps to ATP hydrolysis

Dispersion of Silver Nanoparticles into Polymer Matrix Dry Adhesives to Achieve Antibacterial Properties, Increased Adhesion, and Optical Absorption

A Conserved Tripeptide in CNG and HCN Channels Regulates Ligand Gating by Controlling C-Terminal Oligomerization

Ligand-binding domain subregions contributing to bimodal agonism in cyclic nucleotide-gated channels

Sensitivity of HCN channel deactivation to cAMP is amplified by an S4 mutation combined with activation mode shift

Does Bimodal Agonism in Cyclic Nucleotide-Gated (CNG) Channels Preserve the Classical Binding Site and Pore Structure?

A Charged Residue in the HCN Channel C-Linker Stabilizes the Open State

A single residue exerts two contrasting effects on autoinhibition of HCN channels

Failure of a single-headed kinesin to track parallel to microtubule protofilaments

HCN C-Terminal Region Speeds Activation Independently of Autoinhibition

Role of Interactions between Transmembrane and C-Terminal Regions in Voltage-Dependent Activation of HCN4 Channels

C-Linker of cyclic nucleotide-gated channels controls coupling of ligand binding to channel gating

Fluorescence Investigations of the Rate‐Limiting Step in the HCN Ion Channel Deactivation Pathway

One-Headed Kinesin Derivatives Move by a Nonprocessive, Low-Duty Ratio Mechanism Unlike That of Two-Headed Kinesin

Efficient coupling of ligand binding to channel opening by the binding domain of a modulatory (beta) subunit of the olfactory cyclic nucleotide-gated channel

Rapid Deactivation of An HCN Channel Indicates a New Mechanism Using the Cyclic AMP-Sensing Domain, Different From Autoinhibition and Open State Trapping

Modulation of HCN Channel Deactivation Kinetics by CAMP and Depolarization Can Be Amplified by Mode Shift

Subunit Interactions in Dimeric Kinesin Heavy Chain Derivatives That Lack the Kinesin Rod

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