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Determination of Potential Lead Compound from Magnolia officinalis for Alzheimer's Disease through Pharmacokinetic Prediction, Molecular Docking, Dynamic Simulation, and Experimental Validation

International journal of molecular sciences, 2024-10, Vol.25 (19), p.10507

2024

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Biological Evaluation and Docking Analysis of Potent BACE1 Inhibitors from Boesenbergia rotunda

Nutrients, 2019-03, Vol.11 (3), p.662

2019

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Decursin prevents melanogenesis by suppressing MITF expression through the regulation of PKA/CREB, MAPKs, and PI3K/Akt/GSK-3β cascades

Biomedicine & pharmacotherapy, 2022-03, Vol.147, p.112651-112651, Article 112651

2022

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Discovery of Nobiletin from Citrus Peel as a Potent Inhibitor of β-Amyloid Peptide Toxicity

Nutrients, 2019-11, Vol.11 (11), p.2648

2019

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Discovery of Pinostrobin as a Melanogenic Agent in cAMP/PKA and p38 MAPK Signaling Pathway

Nutrients, 2022-09, Vol.14 (18), p.3713

2022

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Protective effect of sargahydroquinoic acid against Aβ25–35-evoked damage via PI3K/Akt mediated Nrf2 antioxidant defense system

Biomedicine & pharmacotherapy, 2021-12, Vol.144, p.112271, Article 112271

2021

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In Silico Docking and In Vitro Approaches towards BACE1 and Cholinesterases Inhibitory Effect of Citrus Flavanones

Molecules (Basel, Switzerland), 2018-06, Vol.23 (7), p.1509

2018

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Investigating the Potential Anti-Alzheimer’s Disease Mechanism of Marine Polyphenols: Insights from Network Pharmacology and Molecular Docking

Marine drugs, 2023-11, Vol.21 (11), p.580

2023

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Multifaceted neuroprotective effects of (-)-epigallocatechin-3-gallate (EGCG) in Alzheimer’s disease: an overview of pre-clinical studies focused on β-amyloid peptide

Food science and human wellness, 2022-05, Vol.11 (3), p.483-493

2022

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Inhibitory Effects of Key Compounds Isolated from Corni fructus on BACE1 Activity

Phytotherapy research, 2012-11, Vol.26 (11), p.1714-1718

2012

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Neuroprotective Effects of Baicalein, Wogonin, and Oroxylin A on Amyloid Beta-Induced Toxicity via NF-κB/MAPK Pathway Modulation

Molecules (Basel, Switzerland), 2020-11, Vol.25 (21), p.5087

2020

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Anti-Neuroinflammatory Property of Phlorotannins from Ecklonia cava on Aβ25-35-Induced Damage in PC12 Cells

Marine drugs, 2018-12, Vol.17 (1), p.7

2018

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Baicalein as a Potential Inhibitor against BACE1 and AChE: Mechanistic Comprehension through In Vitro and Computational Approaches

Nutrients, 2019-11, Vol.11 (11), p.2694

2019

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Polymethoxyflavones: Novel β-Secretase (BACE1) Inhibitors from Citrus Peels

Nutrients, 2017-09, Vol.9 (9), p.973

2017

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Discovery of Natural Inhibitors of Cholinesterases from Hydrangea : In Vitro and In Silico Approaches

Nutrients, 2021-01, Vol.13 (1), p.254

2021

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Dieckol Ameliorates Aβ Production via PI3K/Akt/GSK-3β Regulated APP Processing in SweAPP N2a Cell

Marine drugs, 2021-03, Vol.19 (3), p.152

2021

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Gamma-linolenic acid ameliorates Aβ-induced neuroinflammation through NF-κB and MAPK signalling pathways

Journal of functional foods, 2018-03, Vol.42, p.30-37

2018

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The Role of Fucoxanthin as a Potent Nrf2 Activator via Akt/GSK-3β/Fyn Axis against Amyloid-β Peptide-Induced Oxidative Damage

Antioxidants, 2023-03, Vol.12 (3), p.629

2023

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Discovery of polymethoxyflavones from black ginger (Kaempferia parviflora) as potential β-secretase (BACE1) inhibitors

Journal of functional foods, 2016-01, Vol.20, p.567-574

2016

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Protective Effects of Red Ginseng Oil against Aβ25–35-Induced Neuronal Apoptosis and Inflammation in PC12 Cells

International journal of molecular sciences, 2017-10, Vol.18 (10), p.2218

2017

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Eugenitol ameliorates memory impairments in 5XFAD mice by reducing Aβ plaques and neuroinflammation

Biomedicine & pharmacotherapy, 2022-04, Vol.148, p.112763, Article 112763

2022

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The Identification of Biochanin A as a Potent and Selective β-Site App-Cleaving Enzyme 1 (Bace1) Inhibitor

Nutrients, 2016-10, Vol.8 (10), p.637

2016

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Discovery of Sulforaphane as a Potent BACE1 Inhibitor Based on Kinetics and Computational Studies

Nutrients, 2020-10, Vol.12 (10), p.3026

2020

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Biological and Computational Studies for Dual Cholinesterases Inhibitory Effect of Zerumbone

Nutrients, 2020-04, Vol.12 (5), p.1215

2020

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Oleic acid ameliorates Aβ-induced inflammation by downregulation of COX-2 and iNOS via NFκB signaling pathway

Journal of functional foods, 2015-04, Vol.14, p.1-11

2015

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Determination of Potential Lead Compound from Magnolia officinalis for Alzheimer's Disease through Pharmacokinetic Prediction, Molecular Docking, Dynamic Simulation, and Experimental Validation

Biological Evaluation and Docking Analysis of Potent BACE1 Inhibitors from Boesenbergia rotunda

Decursin prevents melanogenesis by suppressing MITF expression through the regulation of PKA/CREB, MAPKs, and PI3K/Akt/GSK-3β cascades

Discovery of Nobiletin from Citrus Peel as a Potent Inhibitor of β-Amyloid Peptide Toxicity

Discovery of Pinostrobin as a Melanogenic Agent in cAMP/PKA and p38 MAPK Signaling Pathway

Protective effect of sargahydroquinoic acid against Aβ25–35-evoked damage via PI3K/Akt mediated Nrf2 antioxidant defense system

In Silico Docking and In Vitro Approaches towards BACE1 and Cholinesterases Inhibitory Effect of Citrus Flavanones

Investigating the Potential Anti-Alzheimer’s Disease Mechanism of Marine Polyphenols: Insights from Network Pharmacology and Molecular Docking

Multifaceted neuroprotective effects of (-)-epigallocatechin-3-gallate (EGCG) in Alzheimer’s disease: an overview of pre-clinical studies focused on β-amyloid peptide

Inhibitory Effects of Key Compounds Isolated from Corni fructus on BACE1 Activity

Neuroprotective Effects of Baicalein, Wogonin, and Oroxylin A on Amyloid Beta-Induced Toxicity via NF-κB/MAPK Pathway Modulation

Anti-Neuroinflammatory Property of Phlorotannins from Ecklonia cava on Aβ25-35-Induced Damage in PC12 Cells

Baicalein as a Potential Inhibitor against BACE1 and AChE: Mechanistic Comprehension through In Vitro and Computational Approaches

Polymethoxyflavones: Novel β-Secretase (BACE1) Inhibitors from Citrus Peels

Discovery of Natural Inhibitors of Cholinesterases from Hydrangea : In Vitro and In Silico Approaches

Dieckol Ameliorates Aβ Production via PI3K/Akt/GSK-3β Regulated APP Processing in SweAPP N2a Cell

Gamma-linolenic acid ameliorates Aβ-induced neuroinflammation through NF-κB and MAPK signalling pathways

The Role of Fucoxanthin as a Potent Nrf2 Activator via Akt/GSK-3β/Fyn Axis against Amyloid-β Peptide-Induced Oxidative Damage

Discovery of polymethoxyflavones from black ginger (Kaempferia parviflora) as potential β-secretase (BACE1) inhibitors

Protective Effects of Red Ginseng Oil against Aβ25–35-Induced Neuronal Apoptosis and Inflammation in PC12 Cells

Eugenitol ameliorates memory impairments in 5XFAD mice by reducing Aβ plaques and neuroinflammation

The Identification of Biochanin A as a Potent and Selective β-Site App-Cleaving Enzyme 1 (Bace1) Inhibitor

Discovery of Sulforaphane as a Potent BACE1 Inhibitor Based on Kinetics and Computational Studies

Biological and Computational Studies for Dual Cholinesterases Inhibitory Effect of Zerumbone

Oleic acid ameliorates Aβ-induced inflammation by downregulation of COX-2 and iNOS via NFκB signaling pathway

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