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The relevance of iron in the pathogenesis of Parkinson’s disease

Journal of neurochemistry, 2011-09, Vol.118 (6), p.939-957

2011

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The therapeutic potential of monoamine oxidase inhibitors

Nature reviews. Neuroscience, 2006-04, Vol.7 (4), p.295-309

2006

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Monoamine oxidase inhibitors, and iron chelators in depressive illness and neurodegenerative diseases

Journal of Neural Transmission, 2018-11, Vol.125 (11), p.1719-1733

Youdim, Moussa B. H.

2018

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The Neuroprotective Activities of the Novel Multi-Target Iron-Chelators in Models of Alzheimer's Disease, Amyotrophic Lateral Sclerosis and Aging

Cells (Basel, Switzerland), 2023-02, Vol.12 (5), p.763

2023

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Iron, brain ageing and neurodegenerative disorders

Nature reviews. Neuroscience, 2004-11, Vol.5 (11), p.863-873

2004

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Monoamine oxidase A upregulated by chronic intermittent hypoxia activates indoleamine 2,3-dioxygenase and neurodegeneration

PloS one, 2017-06, Vol.12 (6), p.e0177940-e0177940

2017

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Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (‐)‐epigallocatechin‐3‐gallate: implications for neurodegenerative diseases

Journal of neurochemistry, 2004-03, Vol.88 (6), p.1555-1569

2004

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Neuroprotective and neuritogenic activities of novel multimodal iron-chelating drugs in motor-neuron-like NSC-34 cells and transgenic mouse model of amyotrophic lateral sclerosis

The FASEB journal, 2009-11, Vol.23 (11), p.3766-3779

2009

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M30 Antagonizes Indoleamine 2,3-Dioxygenase Activation and Neurodegeneration Induced by Corticosterone in the Hippocampus

PloS one, 2016-11, Vol.11 (11), p.e0166966-e0166966

2016

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neuroprotective mechanism of 1-(R)-aminoindan, the major metabolite of the anti-parkinsonian drug rasagiline

Journal of neurochemistry, 2010-03, Vol.112 (5), p.1131-1137

2010

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Site-Activated Chelators Targeting Acetylcholinesterase and Monoamine Oxidase for Alzheimer’s Therapy

ACS chemical biology, 2010-06, Vol.5 (6), p.603-610

2010

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Simultaneous Manipulation of Multiple Brain Targets by Green Tea Catechins: A Potential Neuroprotective Strategy for Alzheimer and Parkinson Diseases

CNS neuroscience & therapeutics, 2008, Vol.14 (4), p.352-365

2008

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Aminoindan and hydroxyaminoindan, metabolites of rasagiline and ladostigil, respectively, exert neuroprotective properties in vitro

Journal of neurochemistry, 2007-10, Vol.103 (2), p.500-508

2007

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Prevention and restoration of lactacystin-induced nigrostriatal dopamine neuron degeneration by novel brain-permeable iron chelators

The FASEB journal, 2007-12, Vol.21 (14), p.3835-3844

2007

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Therapeutic targets and potential of the novel brain- permeable multifunctional iron chelator-monoamine oxidase inhibitor drug, M-30, for the treatment of Alzheimer's disease

Journal of neurochemistry, 2007, Vol.100 (2), p.490-502

2007

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Novel multifunctional neuroprotective iron chelator‐monoamine oxidase inhibitor drugs for neurodegenerative diseases: in vitro studies on antioxidant activity, prevention of lipid peroxide formation and monoamine oxidase inhibition

Journal of neurochemistry, 2005-10, Vol.95 (1), p.68-78

2005

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Metallocorroles as cytoprotective agents against oxidative and nitrative stress in cellular models of neurodegeneration

Journal of neurochemistry, 2010-04, Vol.113 (2), p.363-373

2010

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Green tea catechins as brain-permeable, natural iron chelators-antioxidants for the treatment of neurodegenerative disorders

Molecular nutrition & food research, 2006-02, Vol.50 (2), p.229-234

2006

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N-Methyl, N-propynyl-2-phenylethylamine (MPPE), a Selegiline Analog, Attenuates MPTP-induced Dopaminergic Toxicity with Guaranteed Behavioral Safety: Involvement of Inhibitions of Mitochondrial Oxidative Burdens and p53 Gene-elicited Pro-apoptotic Change

Molecular neurobiology, 2016-11, Vol.53 (9), p.6251-6269

2016

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Green tea polyphenol (-)-epigallocatechin-3-gallate promotes the rapid protein kinase C- and proteasome-mediated degradation of Bad: implications for neuroprotection

Journal of neurochemistry, 2007-02, Vol.100 (4), p.992-1002

2007

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Multifunctional Neuroprotective Derivatives of Rasagiline as Anti-Alzheimer's Disease Drugs

Neurotherapeutics, 2009, Vol.6 (1), p.163-174

2009

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Ladostigil: a novel multimodal neuroprotective drug with cholinesterase and brain-selective monoamine oxidase inhibitory activities for Alzheimer's disease treatment

Current drug targets, 2012-04, Vol.13 (4), p.483-494

2012

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Comparison of neuroprotective and neurorestorative capabilities of rasagiline and selegiline against lactacystin-induced nigrostriatal dopaminergic degeneration

Journal of neurochemistry, 2008-06, Vol.105 (5), p.1970-1978

2008

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Regulation of Bcl-2 family proteins, neurotrophic factors, and APP processing in the neurorescue activity of propargylamine

The FASEB journal, 2005-11, Vol.19 (13), p.1899-1901

2005

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Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness

British journal of pharmacology, 2006-01, Vol.147 (S1), p.S287-S296

2006

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The relevance of iron in the pathogenesis of Parkinson’s disease

The therapeutic potential of monoamine oxidase inhibitors

Monoamine oxidase inhibitors, and iron chelators in depressive illness and neurodegenerative diseases

The Neuroprotective Activities of the Novel Multi-Target Iron-Chelators in Models of Alzheimer's Disease, Amyotrophic Lateral Sclerosis and Aging

Iron, brain ageing and neurodegenerative disorders

Monoamine oxidase A upregulated by chronic intermittent hypoxia activates indoleamine 2,3-dioxygenase and neurodegeneration

Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (‐)‐epigallocatechin‐3‐gallate: implications for neurodegenerative diseases

Neuroprotective and neuritogenic activities of novel multimodal iron-chelating drugs in motor-neuron-like NSC-34 cells and transgenic mouse model of amyotrophic lateral sclerosis

M30 Antagonizes Indoleamine 2,3-Dioxygenase Activation and Neurodegeneration Induced by Corticosterone in the Hippocampus

neuroprotective mechanism of 1-(R)-aminoindan, the major metabolite of the anti-parkinsonian drug rasagiline

Site-Activated Chelators Targeting Acetylcholinesterase and Monoamine Oxidase for Alzheimer’s Therapy

Simultaneous Manipulation of Multiple Brain Targets by Green Tea Catechins: A Potential Neuroprotective Strategy for Alzheimer and Parkinson Diseases

Aminoindan and hydroxyaminoindan, metabolites of rasagiline and ladostigil, respectively, exert neuroprotective properties in vitro

Prevention and restoration of lactacystin-induced nigrostriatal dopamine neuron degeneration by novel brain-permeable iron chelators

Therapeutic targets and potential of the novel brain- permeable multifunctional iron chelator-monoamine oxidase inhibitor drug, M-30, for the treatment of Alzheimer's disease

Novel multifunctional neuroprotective iron chelator‐monoamine oxidase inhibitor drugs for neurodegenerative diseases: in vitro studies on antioxidant activity, prevention of lipid peroxide formation and monoamine oxidase inhibition

Metallocorroles as cytoprotective agents against oxidative and nitrative stress in cellular models of neurodegeneration

Green tea catechins as brain-permeable, natural iron chelators-antioxidants for the treatment of neurodegenerative disorders

N-Methyl, N-propynyl-2-phenylethylamine (MPPE), a Selegiline Analog, Attenuates MPTP-induced Dopaminergic Toxicity with Guaranteed Behavioral Safety: Involvement of Inhibitions of Mitochondrial Oxidative Burdens and p53 Gene-elicited Pro-apoptotic Change

Green tea polyphenol (-)-epigallocatechin-3-gallate promotes the rapid protein kinase C- and proteasome-mediated degradation of Bad: implications for neuroprotection

Multifunctional Neuroprotective Derivatives of Rasagiline as Anti-Alzheimer's Disease Drugs

Ladostigil: a novel multimodal neuroprotective drug with cholinesterase and brain-selective monoamine oxidase inhibitory activities for Alzheimer's disease treatment

Comparison of neuroprotective and neurorestorative capabilities of rasagiline and selegiline against lactacystin-induced nigrostriatal dopaminergic degeneration

Regulation of Bcl-2 family proteins, neurotrophic factors, and APP processing in the neurorescue activity of propargylamine

Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness

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