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Novel molecular targets of the neuroprotective/neurorescue multimodal iron chelating drug M30 in the mouse brain

Neuroscience, 2011-08, Vol.189, p.345-358

2011

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Green tea polyphenol (–)‐epigallocatechin‐3‐gallate induces neurorescue of long‐term serum‐deprived PC12 cells and promotes neurite outgrowth

Journal of neurochemistry, 2005-06, Vol.93 (5), p.1157-1167

2005

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Reduction of iron‐regulated amyloid precursor protein and β‐amyloid peptide by (–)‐epigallocatechin‐3‐gallate in cell cultures: implications for iron chelation in Alzheimer's disease

Journal of neurochemistry, 2006-04, Vol.97 (2), p.527-536

2006

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Phosphorylation of CHIP at Ser20 by Cdk5 promotes tAIF-mediated neuronal death

Cell death and differentiation, 2016-02, Vol.23 (2), p.333-346

2016

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Brain iron pathways and their relevance to Parkinson's disease

Journal of neurochemistry, 2001-10, Vol.79 (2), p.225-236

2001

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Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes

Journal of Neural Transmission, 2004-12, Vol.111 (12), p.1543-1573

2004

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Up-regulation of hypoxia-inducible factor (HIF)-1α and HIF-target genes in cortical neurons by the novel multifunctional iron chelator anti-Alzheimer drug, M30

Current Alzheimer research, 2010-06, Vol.7 (4), p.300-306

2010

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From antioxidant chelators to site-activated multi-target chelators targeting hypoxia inducing factor, beta-amyloid, acetylcholinesterase and monoamine oxidase A/B

Mini reviews in medicinal chemistry, 2012-05, Vol.12 (5), p.364-370

2012

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Environmental factors and movement disorders

Journal of the neurological sciences, 2015-10, Vol.357, p.e477-e478

2015

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CNS Targets for multi-functional drugs in the treatment of Alzheimer's and Parkinson's diseases

Journal of Neural Transmission, 2005-04, Vol.112 (4), p.519-537

2005

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Novel bifunctional drugs targeting monoamine oxidase inhibition and iron chelation as an approach to neuroprotection in Parkinson’s disease and other neurodegenerative diseases

Journal of Neural Transmission, 2004-10, Vol.111 (10-11), p.1455-1471

2004

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Social-cooperation differs from individual behavior in hypothalamic and striatal monoamine function: Evidence from a laboratory rat model

Behavioural brain research, 2012-06, Vol.232 (1), p.252-263

2012

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Altered Brain Metabolism of Iron as a Cause of Neurodegenerative Diseases?

Journal of neurochemistry, 1994-09, Vol.63 (3), p.793-807

1994

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Apomorphine protects against MPTP-induced neurotoxicity in mice

Movement disorders, 1999-07, Vol.14 (4), p.612-618

1999

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cDNA gene expression profile of rat hippocampus after chronic treatment with antidepressant drugs

Journal of Neural Transmission, 2003-12, Vol.110 (12), p.1413-1436

2003

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Brain catalase in the streptozotocin-rat model of sporadic Alzheimer’s disease treated with the iron chelator–monoamine oxidase inhibitor, M30

Journal of Neural Transmission, 2015-04, Vol.122 (4), p.559-564

2015

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N-Propargylamine protects SH-SY5Y cells from apoptosis induced by an endogenous neurotoxin, N-methyl(R)salsolinol, through stabilization of mitochondrial membrane and induction of anti-apoptotic Bcl-2

Journal of Neural Transmission, 2006-01, Vol.113 (1), p.21-32

2006

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Dopamine and serotonin metabolism in response to chronic administration of fluvoxamine and haloperidol combined treatment

Journal of Neural Transmission, 2007-11, Vol.114 (11), p.1443-1454

2007

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Monoamine oxidase-inhibition and MPTP-induced neurotoxicity in the non-human primate : comparison of rasagiline (TVP 1012) with selegiline

Journal of Neural Transmission, 2001-01, Vol.108 (8-9), p.985-1009

2001

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Nature of Inhibition of Mitochondrial Respiratory Complex I by 6‐Hydroxydopamine

Journal of neurochemistry, 1996-05, Vol.66 (5), p.2004-2010

1996

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Selective Increase of Iron in Substantia Nigra Zona Compacta of Parkinsonian Brains

Journal of neurochemistry, 1991-03, Vol.56 (3), p.978-982

1991

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Influence of neuromelanin on oxidative pathways within the human substantia nigra

Neurotoxicology and Teratology, 2002-09, Vol.24 (5), p.621-628

2002

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Iron‐Melanin Complex in Substantia Nigra of Parkinsonian Brains: An X‐Ray Microanalysis

Journal of neurochemistry, 1992-09, Vol.59 (3), p.1168-1171

1992

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Iron‐Melanin Interaction and Lipid Peroxidation: Implications for Parkinson's Disease

Journal of neurochemistry, 1991-11, Vol.57 (5), p.1609-1614

1991

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1277 – The role of GABA-A receptor in the synergism between SSRI and antipsychotics in schizophrenia

European psychiatry, 2013, Vol.28, p.1-1

2013

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Novel molecular targets of the neuroprotective/neurorescue multimodal iron chelating drug M30 in the mouse brain

Green tea polyphenol (–)‐epigallocatechin‐3‐gallate induces neurorescue of long‐term serum‐deprived PC12 cells and promotes neurite outgrowth

Reduction of iron‐regulated amyloid precursor protein and β‐amyloid peptide by (–)‐epigallocatechin‐3‐gallate in cell cultures: implications for iron chelation in Alzheimer's disease

Phosphorylation of CHIP at Ser20 by Cdk5 promotes tAIF-mediated neuronal death

Brain iron pathways and their relevance to Parkinson's disease

Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated proteins, cell adhesion/cellular matrix and vesicle trafficking genes

Up-regulation of hypoxia-inducible factor (HIF)-1α and HIF-target genes in cortical neurons by the novel multifunctional iron chelator anti-Alzheimer drug, M30

From antioxidant chelators to site-activated multi-target chelators targeting hypoxia inducing factor, beta-amyloid, acetylcholinesterase and monoamine oxidase A/B

Environmental factors and movement disorders

CNS Targets for multi-functional drugs in the treatment of Alzheimer's and Parkinson's diseases

Novel bifunctional drugs targeting monoamine oxidase inhibition and iron chelation as an approach to neuroprotection in Parkinson’s disease and other neurodegenerative diseases

Social-cooperation differs from individual behavior in hypothalamic and striatal monoamine function: Evidence from a laboratory rat model

Altered Brain Metabolism of Iron as a Cause of Neurodegenerative Diseases?

Apomorphine protects against MPTP-induced neurotoxicity in mice

cDNA gene expression profile of rat hippocampus after chronic treatment with antidepressant drugs

Brain catalase in the streptozotocin-rat model of sporadic Alzheimer’s disease treated with the iron chelator–monoamine oxidase inhibitor, M30

N-Propargylamine protects SH-SY5Y cells from apoptosis induced by an endogenous neurotoxin, N-methyl(R)salsolinol, through stabilization of mitochondrial membrane and induction of anti-apoptotic Bcl-2

Dopamine and serotonin metabolism in response to chronic administration of fluvoxamine and haloperidol combined treatment

Monoamine oxidase-inhibition and MPTP-induced neurotoxicity in the non-human primate : comparison of rasagiline (TVP 1012) with selegiline

Nature of Inhibition of Mitochondrial Respiratory Complex I by 6‐Hydroxydopamine

Selective Increase of Iron in Substantia Nigra Zona Compacta of Parkinsonian Brains

Influence of neuromelanin on oxidative pathways within the human substantia nigra

Iron‐Melanin Complex in Substantia Nigra of Parkinsonian Brains: An X‐Ray Microanalysis

Iron‐Melanin Interaction and Lipid Peroxidation: Implications for Parkinson's Disease

1277 – The role of GABA-A receptor in the synergism between SSRI and antipsychotics in schizophrenia

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