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Prodrug strategy for cancer cell-specific targeting: A recent overview

European journal of medicinal chemistry, 2017-10, Vol.139, p.542-563

2017

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Small-Molecule Modulators of the Hypoxia-Inducible Factor Pathway: Development and Therapeutic Applications

Journal of medicinal chemistry, 2019-06, Vol.62 (12), p.5725-5749

2019

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Forward or Backward: Lessons Learned from Small Molecule Drugs Approved by FDA from 2012 to 2022

Molecules (Basel, Switzerland), 2023-12, Vol.28 (24), p.7941

2023

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A hydrogen peroxide responsive prodrug of Keap1-Nrf2 inhibitor for improving oral absorption and selective activation in inflammatory conditions

Redox biology, 2020-07, Vol.34, p.101565-101565, Article 101565

2020

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Design, synthesis, and biological evaluation of arylmethylpiperidines as Kv1.5 potassium channel inhibitors

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.462-471

2022

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Modulation of protein fate decision by small molecules: targeting molecular chaperone machinery

Acta pharmaceutica Sinica. B, 2020-10, Vol.10 (10), p.1904-1925

2020

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Synthesis and evaluation of anti-tubercular and antibacterial activities of new 4-(2,6-dichlorobenzyloxy)phenyl thiazole, oxazole and imidazole derivatives. Part 2

European journal of medicinal chemistry, 2012-03, Vol.49, p.164-171

2012

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'Click Chemistry' Synthesis of Novel Natural Product-Like Caged Xanthones Bearing a 1,2,3-Triazole Moiety with Improved Druglike Properties as Orally Active Antitumor Agents

Molecules (Basel, Switzerland), 2017-10, Vol.22 (11), p.1834

2017

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Synthesis and biological evaluation of baicalein derivatives as potent antitumor agents

Bioorganic & medicinal chemistry letters, 2014-03, Vol.24 (5), p.1334-1338

2014

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Lead Discovery of Type II BRAF V600E Inhibitors Targeting the Structurally Validated DFG-Out Conformation Based upon Selected Fragments

Molecules (Basel, Switzerland), 2016-07, Vol.21 (7), p.879

2016

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Beclin 1-mediated autophagy in hepatocellular carcinoma cells: Implication in anticancer efficiency of oroxylin A via inhibition of mTOR signaling

Cellular signalling, 2012-08, Vol.24 (8), p.1722-1732

2012

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Recent advances on platensimycin: a potential antimicrobial agent

Current medicinal chemistry, 2010-04, Vol.17 (12), p.1139

2010

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Design, synthesis and anti-tubercular evaluation of new 2-acylated and 2-alkylated amino-5-(4-(benzyloxy)phenyl)thiophene-3-carboxylic acid derivatives. Part 1

European journal of medicinal chemistry, 2011-09, Vol.46 (9), p.3551-3563

2011

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Development of Novel Nrf2/ARE Inducers Bearing Pyrazino[2,1-a]isoquinolin Scaffold with Potent In Vitro Efficacy and Enhanced Physicochemical Properties

Molecules (Basel, Switzerland), 2017-09, Vol.22 (9), p.1541

2017

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Non-small molecule PROTACs (NSM-PROTACs): Protein degradation kaleidoscope

Acta pharmaceutica Sinica. B, 2022-07, Vol.12 (7), p.2990-3005

2022

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Gambogic acid promotes apoptosis and resistance to metastatic potential in MDA-MB-231 human breast carcinoma cells

Biochemistry and cell biology, 2012-12, Vol.90 (6), p.718

2012

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Fluid Charging and Gas Reservoir Pressure Evolution of Longmaxi Formation Shale in Southeastern Chongqing

Geofluids, 2022-02, Vol.2022, p.1-8

2022

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Recent Advances in the Discovery of HIF-1α-p300/CBP Inhibitors as Anti-Cancer Agents

Mini reviews in medicinal chemistry, 2018-01, Vol.18 (4), p.296

2018

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Two p53-related metabolic regulators, TIGAR and SCO2, contribute to oroxylin A-mediated glucose metabolism in human hepatoma HepG2 cells

The international journal of biochemistry & cell biology, 2013-07, Vol.45 (7), p.1468-1478

2013

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Inhibitory effects of wogonin on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-9

Toxicology (Amsterdam), 2011-04, Vol.282 (3), p.122-128

2011

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Wogonin induced cytotoxicity in human hepatocellular carcinoma cells by activation of unfolded protein response and inactivation of AKT

Hepatology research, 2013-08, Vol.43 (8), p.890-905

2013

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Gambogic acid inhibits tumor cell adhesion by suppressing integrin β1 and membrane lipid rafts-associated integrin signaling pathway

Biochemical pharmacology, 2011-12, Vol.82 (12), p.1873-1883

2011

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Novel Hydrogen Sulfide Hybrid Derivatives of Keap1-Nrf2 Protein-Protein Interaction Inhibitor Alleviate Inflammation and Oxidative Stress in Acute Experimental Colitis

Antioxidants, 2023-05, Vol.12 (5), p.1062

2023

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Methods for the Discovery and Identification of Small Molecules Targeting Oxidative Stress-Related Protein-Protein Interactions: An Update

Antioxidants, 2022-03, Vol.11 (4), p.619

2022

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Gambogic Acid Deactivates Cytosolic and Mitochondrial Thioredoxins by Covalent Binding to the Functional Domain

Journal of natural products (Washington, D.C.), 2012-06, Vol.75 (6), p.1108-1116

2012

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Prodrug strategy for cancer cell-specific targeting: A recent overview

Small-Molecule Modulators of the Hypoxia-Inducible Factor Pathway: Development and Therapeutic Applications

Forward or Backward: Lessons Learned from Small Molecule Drugs Approved by FDA from 2012 to 2022

A hydrogen peroxide responsive prodrug of Keap1-Nrf2 inhibitor for improving oral absorption and selective activation in inflammatory conditions

Design, synthesis, and biological evaluation of arylmethylpiperidines as Kv1.5 potassium channel inhibitors

Modulation of protein fate decision by small molecules: targeting molecular chaperone machinery

Synthesis and evaluation of anti-tubercular and antibacterial activities of new 4-(2,6-dichlorobenzyloxy)phenyl thiazole, oxazole and imidazole derivatives. Part 2

'Click Chemistry' Synthesis of Novel Natural Product-Like Caged Xanthones Bearing a 1,2,3-Triazole Moiety with Improved Druglike Properties as Orally Active Antitumor Agents

Synthesis and biological evaluation of baicalein derivatives as potent antitumor agents

Lead Discovery of Type II BRAF V600E Inhibitors Targeting the Structurally Validated DFG-Out Conformation Based upon Selected Fragments

Beclin 1-mediated autophagy in hepatocellular carcinoma cells: Implication in anticancer efficiency of oroxylin A via inhibition of mTOR signaling

Recent advances on platensimycin: a potential antimicrobial agent

Design, synthesis and anti-tubercular evaluation of new 2-acylated and 2-alkylated amino-5-(4-(benzyloxy)phenyl)thiophene-3-carboxylic acid derivatives. Part 1

Development of Novel Nrf2/ARE Inducers Bearing Pyrazino[2,1-a]isoquinolin Scaffold with Potent In Vitro Efficacy and Enhanced Physicochemical Properties

Non-small molecule PROTACs (NSM-PROTACs): Protein degradation kaleidoscope

Gambogic acid promotes apoptosis and resistance to metastatic potential in MDA-MB-231 human breast carcinoma cells

Fluid Charging and Gas Reservoir Pressure Evolution of Longmaxi Formation Shale in Southeastern Chongqing

Recent Advances in the Discovery of HIF-1α-p300/CBP Inhibitors as Anti-Cancer Agents

Two p53-related metabolic regulators, TIGAR and SCO2, contribute to oroxylin A-mediated glucose metabolism in human hepatoma HepG2 cells

Inhibitory effects of wogonin on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-9

Wogonin induced cytotoxicity in human hepatocellular carcinoma cells by activation of unfolded protein response and inactivation of AKT

Gambogic acid inhibits tumor cell adhesion by suppressing integrin β1 and membrane lipid rafts-associated integrin signaling pathway

Novel Hydrogen Sulfide Hybrid Derivatives of Keap1-Nrf2 Protein-Protein Interaction Inhibitor Alleviate Inflammation and Oxidative Stress in Acute Experimental Colitis

Methods for the Discovery and Identification of Small Molecules Targeting Oxidative Stress-Related Protein-Protein Interactions: An Update

Gambogic Acid Deactivates Cytosolic and Mitochondrial Thioredoxins by Covalent Binding to the Functional Domain

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