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Genomic destabilization and its associated mutagenesis increase with senescence‐associated phenotype expression

Cancer science, 2021-02, Vol.112 (2), p.515-522

2021

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Aberrations in DNA repair pathways in cancer and therapeutic significances

Seminars in cancer biology, 2019-10, Vol.58, p.29-46

2019

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Complete diastereodivergence in asymmetric 1,6-addition reactions enabled by minimal modification of a chiral catalyst

Nature communications, 2017-03, Vol.8 (1), p.14793-14793, Article 14793

2017

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Highly Regio‑, Diastereo‑, and Enantioselective 1,6- and 1,8-Additions of Azlactones to Di- and Trienyl N‑Acylpyrroles

Journal of the American Chemical Society, 2012-11, Vol.134 (47), p.19370-19373

2012

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Genomic Instability and Cancer Risk Associated with Erroneous DNA Repair

International journal of molecular sciences, 2021-11, Vol.22 (22), p.12254

2021

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Resveratrol and its Related Polyphenols Contribute to the Maintenance of Genome Stability

Scientific reports, 2020-03, Vol.10 (1), p.5388, Article 5388

2020

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Gamma‐irradiated quiescent cells repair directly induced double‐strand breaks but accumulate persistent double‐strand breaks during subsequent DNA replication

Genes to cells : devoted to molecular & cellular mechanisms, 2016-07, Vol.21 (7), p.789-797

2016

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Replication stress triggers microsatellite destabilization and hypermutation leading to clonal expansion in vitro

Nature communications, 2019-09, Vol.10 (1), p.3925-13, Article 3925

2019

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Catalyst‐Enabled Site‐Divergent Stereoselective Michael Reactions: Overriding Intrinsic Reactivity of Enynyl Carbonyl Acceptors

Angewandte Chemie International Edition, 2018-04, Vol.57 (17), p.4732-4736

International ed. in English, 2018

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Unique site-selectivity control in asymmetric Michael addition of azlactone to alkenyl dienyl ketones enabled by P-spiro chiral iminophosphorane catalysis

Chemical communications (Cambridge, England), 2017, Vol.53 (40), p.5495-5498

2017

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Genome destabilization-associated phenotypes arising as a consequence of therapeutic treatment are suppressed by Olaparib

PloS one, 2023-01, Vol.18 (1), p.e0281168-e0281168

2023

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ATM and SIRT6/SNF2H Mediate Transient H2AX Stabilization When DSBs Form by Blocking HUWE1 to Allow Efficient γH2AX Foci Formation

Cell reports (Cambridge), 2015-12, Vol.13 (12), p.2728-2740

2015

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Single base substitution signatures 17a, 17b, and 40 are induced by γ-ray irradiation in association with increased reactive oxidative species

Heliyon, 2024-03, Vol.10 (6), p.e28044-e28044, Article e28044

2024

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Sensitization of Cancer Cells to Radiation and Topoisomerase I Inhibitor Camptothecin Using Inhibitors of PARP and Other Signaling Molecules

Cancers, 2018-09, Vol.10 (10), p.364

2018

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Origin of High Regio‑, Diastereo‑, and Enantioselectivities in 1,6-Addition of Azlactones to Dienyl N‑Acylpyrroles: A Computational Study

Journal of organic chemistry, 2017-01, Vol.82 (1), p.541-548

2017

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Induction of Cancerous Stem Cells during Embryonic Stem Cell Differentiation

The Journal of biological chemistry, 2012-10, Vol.287 (44), p.36777-36791

2012

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Genomic-Destabilization-Associated Mutagenesis and Clonal Evolution of Cells with Mutations in Tumor-Suppressor Genes

Cancers, 2019-10, Vol.11 (11), p.1643

2019

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The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine

Journal of cellular biochemistry, 2008-09, Vol.105 (1), p.245-254

2008

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DNA lesions induced by replication stress trigger mitotic aberration and tetraploidy development

PloS one, 2010-01, Vol.5 (1), p.e8821

2010

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Echoed induction of nucleotide variants and chromosomal structural variants in cancer cells

Scientific reports, 2022-12, Vol.12 (1), p.20964-20964, Article 20964

2022

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Onset of quiescence following p53 mediated down-regulation of H2AX in normal cells

PloS one, 2011-08, Vol.6 (8), p.e23432

2011

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The Arf/p53 Protein Module, Which Induces Apoptosis, Down-regulates Histone H2AX to Allow Normal Cells to Survive in the Presence of Anti-cancer Drugs

The Journal of biological chemistry, 2013-05, Vol.288 (19), p.13269-13277

2013

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Replication-stress-associated DSBs induced by ionizing radiation risk genomic destabilization and associated clonal evolution

iScience, 2021-04, Vol.24 (4), p.102313, Article 102313

2021

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Preparation and Characterization of Highly Heat-Resistant Organic-Inorganic Hybrid Materials Made from Two-Component Polydimethylsiloxane

Molecular Crystals and Liquid Crystals, 2014-07, Vol.597 (1), p.59-64

2014

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Genomic Destabilization Triggered by Replication Stress during Senescence

Cancers, 2017-11, Vol.9 (12), p.159

2017

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Genomic destabilization and its associated mutagenesis increase with senescence‐associated phenotype expression

Aberrations in DNA repair pathways in cancer and therapeutic significances

Complete diastereodivergence in asymmetric 1,6-addition reactions enabled by minimal modification of a chiral catalyst

Highly Regio‑, Diastereo‑, and Enantioselective 1,6- and 1,8-Additions of Azlactones to Di- and Trienyl N‑Acylpyrroles

Genomic Instability and Cancer Risk Associated with Erroneous DNA Repair

Resveratrol and its Related Polyphenols Contribute to the Maintenance of Genome Stability

Gamma‐irradiated quiescent cells repair directly induced double‐strand breaks but accumulate persistent double‐strand breaks during subsequent DNA replication

Replication stress triggers microsatellite destabilization and hypermutation leading to clonal expansion in vitro

Catalyst‐Enabled Site‐Divergent Stereoselective Michael Reactions: Overriding Intrinsic Reactivity of Enynyl Carbonyl Acceptors

Unique site-selectivity control in asymmetric Michael addition of azlactone to alkenyl dienyl ketones enabled by P-spiro chiral iminophosphorane catalysis

Genome destabilization-associated phenotypes arising as a consequence of therapeutic treatment are suppressed by Olaparib

ATM and SIRT6/SNF2H Mediate Transient H2AX Stabilization When DSBs Form by Blocking HUWE1 to Allow Efficient γH2AX Foci Formation

Single base substitution signatures 17a, 17b, and 40 are induced by γ-ray irradiation in association with increased reactive oxidative species

Sensitization of Cancer Cells to Radiation and Topoisomerase I Inhibitor Camptothecin Using Inhibitors of PARP and Other Signaling Molecules

Origin of High Regio‑, Diastereo‑, and Enantioselectivities in 1,6-Addition of Azlactones to Dienyl N‑Acylpyrroles: A Computational Study

Induction of Cancerous Stem Cells during Embryonic Stem Cell Differentiation

Genomic-Destabilization-Associated Mutagenesis and Clonal Evolution of Cells with Mutations in Tumor-Suppressor Genes

The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine

DNA lesions induced by replication stress trigger mitotic aberration and tetraploidy development

Echoed induction of nucleotide variants and chromosomal structural variants in cancer cells

Onset of quiescence following p53 mediated down-regulation of H2AX in normal cells

The Arf/p53 Protein Module, Which Induces Apoptosis, Down-regulates Histone H2AX to Allow Normal Cells to Survive in the Presence of Anti-cancer Drugs

Replication-stress-associated DSBs induced by ionizing radiation risk genomic destabilization and associated clonal evolution

Preparation and Characterization of Highly Heat-Resistant Organic-Inorganic Hybrid Materials Made from Two-Component Polydimethylsiloxane

Genomic Destabilization Triggered by Replication Stress during Senescence

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