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Estrogenic Endocrine-Disrupting Chemicals: Molecular Mechanisms of Actions on Putative Human Diseases

Journal of toxicology and environmental health. Part B, Critical reviews, 2014-04, Vol.17 (3), p.127-174

2014

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A New Synthetic Histone Deacetylase Inhibitor, MHY2256, Induces Apoptosis and Autophagy Cell Death in Endometrial Cancer Cells via p53 Acetylation

International journal of molecular sciences, 2018-09, Vol.19 (9), p.2743

2018

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Afrocyclamin A, a triterpene saponin, induces apoptosis and autophagic cell death via the PI3K/Akt/mTOR pathway in human prostate cancer cells

Phytomedicine (Stuttgart), 2018-12, Vol.51, p.139-150

2018

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Anti-cancer effect of doxorubicin is mediated by downregulation of HMG-Co A reductase via inhibition of EGFR/Src pathway

Laboratory investigation, 2019-08, Vol.99 (8), p.1157-1172

2019

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Knockdown of Pyruvate Kinase M2 Inhibits Cell Proliferation, Metabolism, and Migration in Renal Cell Carcinoma

International journal of molecular sciences, 2019-11, Vol.20 (22), p.5622

2019

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Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumors

Carcinogenesis (New York), 2011-06, Vol.32 (6), p.836-842

2011

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Targeting X chromosome-linked inhibitor of apoptosis protein in mucoepidermoid carcinoma of the head and neck: A novel therapeutic strategy using nitidine chloride

Journal of molecular medicine (Berlin, Germany), 2020-11, Vol.98 (11), p.1591-1602

2020

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Nur77 agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptor-dependent and nuclear receptor-independent pathways

Cancer research (Chicago, Ill.), 2007-01, Vol.67 (2), p.674-683

2007

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PKM2 Knockdown Induces Autophagic Cell Death via AKT/mTOR Pathway in Human Prostate Cancer Cells

Cellular physiology and biochemistry, 2019, Vol.52 (6), p.1535-1552

2019

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Activation of Nur77 by Selected 1,1-Bis(3′-indolyl)-1-(p-substituted phenyl)methanes Induces Apoptosis through Nuclear Pathways

The Journal of biological chemistry, 2005-07, Vol.280 (26), p.24903-24914

2005

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Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells

Cancer research (Chicago, Ill.), 2007-04, Vol.67 (7), p.3286-3294

2007

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Isoharringtonine Induces Apoptosis of Non-Small Cell Lung Cancer Cells in Tumorspheroids via the Intrinsic Pathway

Biomolecules (Basel, Switzerland), 2020-11, Vol.10 (11), p.1521

2020

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Suppressor of Variegation 3-9 Homolog 2, a Novel Binding Protein of Translationally Controlled Tumor Protein, Regulates Cancer Cell Proliferation

Biomolecules & therapeutics, 2019-03, Vol.27 (2), p.231-239

2019

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CCAAT/Enhancer Binding Protein-β is a Mediator of Keratinocyte Survival and Skin Tumorigenesis Involving Oncogenic Ras Signaling

Proceedings of the National Academy of Sciences - PNAS, 2002-01, Vol.99 (1), p.207-212

2002

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C/EBPβ Is a Transcriptional Regulator of Wee1 at the G₂/M Phase of the Cell Cycle

Cells (Basel, Switzerland), 2019-02, Vol.8 (2), p.145

2019

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Activation of COUP-TFI by a Novel Diindolylmethane Derivative

Cells (Basel, Switzerland), 2019-03, Vol.8 (3), p.220

2019

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Problems for risk assessment of endocrine-active estrogenic compounds

Environmental health perspectives, 2002-12, Vol.110 (suppl 6), p.925-929

2002

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p21 Expression Is Induced by Activation of Nuclear Nerve Growth Factor–Induced Bα (Nur77) in Pancreatic Cancer Cells

Molecular cancer research, 2009-07, Vol.7 (7), p.1169-1178

2009

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1,1-bis(3′-indolyl)-1-(p-methoxyphenyl)methane activates Nur77-independent proapoptotic responses in colon cancer cells

Molecular carcinogenesis, 2008-04, Vol.47 (4), p.252-263

2008

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C/EBPα Is a DNA Damage-Inducible p53-Regulated Mediator of the G1 Checkpoint in Keratinocytes

Molecular and Cellular Biology, 2004-12, Vol.24 (24), p.10650-10660

2004

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Inactivation of the Orphan Nuclear Receptor TR3/Nur77 Inhibits Pancreatic Cancer Cell and Tumor Growth

Cancer research (Chicago, Ill.), 2010-09, Vol.70 (17), p.6824-6836

2010

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A new SIRT1 inhibitor, MHY2245, induces autophagy and inhibits energy metabolism via PKM2/mTOR pathway in human ovarian cancer cells

International journal of biological sciences, 2020-01, Vol.16 (11), p.1901-1916

2020

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C/EBPα Is a DNA Damage-Inducible p53-Regulated Mediator of the G 1 Checkpoint in Keratinocytes

Molecular and cellular biology, 2004-12, Vol.24 (24), p.10650-10660

2004

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IL-1[alpha] and IL-1[beta] as alternative biomarkers for risk assessment and the prediction of skin sensitization potency

Journal of toxicology and environmental health. Part A, 2018-01, Vol.81 (17), p.830

2018

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Salinomycin, a p-glycoprotein inhibitor, sensitizes radiation-treated cancer cells by increasing DNA damage and inducing G2 arrest

Investigational new drugs, 2012-08, Vol.30 (4), p.1311-1318

2012

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Estrogenic Endocrine-Disrupting Chemicals: Molecular Mechanisms of Actions on Putative Human Diseases

A New Synthetic Histone Deacetylase Inhibitor, MHY2256, Induces Apoptosis and Autophagy Cell Death in Endometrial Cancer Cells via p53 Acetylation

Afrocyclamin A, a triterpene saponin, induces apoptosis and autophagic cell death via the PI3K/Akt/mTOR pathway in human prostate cancer cells

Anti-cancer effect of doxorubicin is mediated by downregulation of HMG-Co A reductase via inhibition of EGFR/Src pathway

Knockdown of Pyruvate Kinase M2 Inhibits Cell Proliferation, Metabolism, and Migration in Renal Cell Carcinoma

Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumors

Targeting X chromosome-linked inhibitor of apoptosis protein in mucoepidermoid carcinoma of the head and neck: A novel therapeutic strategy using nitidine chloride

Nur77 agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptor-dependent and nuclear receptor-independent pathways

PKM2 Knockdown Induces Autophagic Cell Death via AKT/mTOR Pathway in Human Prostate Cancer Cells

Activation of Nur77 by Selected 1,1-Bis(3′-indolyl)-1-(p-substituted phenyl)methanes Induces Apoptosis through Nuclear Pathways

Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells

Isoharringtonine Induces Apoptosis of Non-Small Cell Lung Cancer Cells in Tumorspheroids via the Intrinsic Pathway

Suppressor of Variegation 3-9 Homolog 2, a Novel Binding Protein of Translationally Controlled Tumor Protein, Regulates Cancer Cell Proliferation

CCAAT/Enhancer Binding Protein-β is a Mediator of Keratinocyte Survival and Skin Tumorigenesis Involving Oncogenic Ras Signaling

C/EBPβ Is a Transcriptional Regulator of Wee1 at the G₂/M Phase of the Cell Cycle

Activation of COUP-TFI by a Novel Diindolylmethane Derivative

Problems for risk assessment of endocrine-active estrogenic compounds

p21 Expression Is Induced by Activation of Nuclear Nerve Growth Factor–Induced Bα (Nur77) in Pancreatic Cancer Cells

1,1-bis(3′-indolyl)-1-(p-methoxyphenyl)methane activates Nur77-independent proapoptotic responses in colon cancer cells

C/EBPα Is a DNA Damage-Inducible p53-Regulated Mediator of the G1 Checkpoint in Keratinocytes

Inactivation of the Orphan Nuclear Receptor TR3/Nur77 Inhibits Pancreatic Cancer Cell and Tumor Growth

A new SIRT1 inhibitor, MHY2245, induces autophagy and inhibits energy metabolism via PKM2/mTOR pathway in human ovarian cancer cells

C/EBPα Is a DNA Damage-Inducible p53-Regulated Mediator of the G 1 Checkpoint in Keratinocytes

IL-1[alpha] and IL-1[beta] as alternative biomarkers for risk assessment and the prediction of skin sensitization potency

Salinomycin, a p-glycoprotein inhibitor, sensitizes radiation-treated cancer cells by increasing DNA damage and inducing G2 arrest

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