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Thioredoxin Reductase 1 Deficiency Reverses Tumor Phenotype and Tumorigenicity of Lung Carcinoma Cells

The Journal of biological chemistry, 2006-05, Vol.281 (19), p.13005-13008

2006

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Delineating the role of glutathione peroxidase 4 in protecting cells against lipid hydroperoxide damage and in Alzheimer's disease

Antioxidants & redox signaling, 2010-04, Vol.12 (7), p.819-827

2010

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Biosynthesis of Selenocysteine, the 21st Amino Acid in the Genetic Code, and a Novel Pathway for Cysteine Biosynthesis

Advances in nutrition (Bethesda, Md.), 2011-03, Vol.2 (2), p.122-128

2011

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Thioredoxin reductase 1 protects against chemically induced hepatocarcinogenesis via control of cellular redox homeostasis

Carcinogenesis (New York), 2012-09, Vol.33 (9), p.1806-1813

2012

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The 15kDa selenoprotein and thioredoxin reductase 1 promote colon cancer by different pathways

PloS one, 2015-04, Vol.10 (4), p.e0124487

2015

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Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery

Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (50), p.21430-21434

2010

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Targeting thioredoxin reductase 1 reduction in cancer cells inhibits self-sufficient growth and DNA replication

PloS one, 2007-10, Vol.2 (10), p.e1112-e1112

2007

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Knockout of the 15 kDa selenoprotein protects against chemically-induced aberrant crypt formation in mice

PloS one, 2012-12, Vol.7 (12), p.e50574

2012

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Abrogated thioredoxin system causes increased sensitivity to TNF-α-induced apoptosis via enrichment of p-ERK 1/2 in the nucleus

PloS one, 2013-09, Vol.8 (9), p.e71427-e71427

2013

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HIF-independent regulation of thioredoxin reductase 1 contributes to the high levels of reactive oxygen species induced by hypoxia

PloS one, 2012-02, Vol.7 (2), p.e30470

2012

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Deficiency in the 15-kDa selenoprotein inhibits tumorigenicity and metastasis of colon cancer cells

Cancer prevention research (Philadelphia, Pa.), 2010-05, Vol.3 (5), p.630-639

2010

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Thioredoxin reductase 1 deficiency enhances selenite toxicity in cancer cells via a thioredoxin-independent mechanism

Biochemical journal, 2012-08, Vol.445 (3), p.423-430

2012

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Selenoproteins regulate macrophage invasiveness and extracellular matrix-related gene expression

BMC immunology, 2009-10, Vol.10 (1), p.57-57, Article 57

2009

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Deficiency in the 15 kDa selenoprotein inhibits human colon cancer cell growth

Nutrients, 2011-09, Vol.3 (9), p.805-817

2011

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Mouse models targeting selenocysteine tRNA expression for elucidating the role of selenoproteins in health and development

Molecules, 2009-09, Vol.14 (9), p.3509-3527

2009

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Selenoproteins that function in cancer prevention and promotion

Biochimica et biophysica acta, 2009-11, Vol.1790 (11), p.1541-1545

2009

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Role of the BLT2, a leukotriene B4 receptor, in Ras transformation

Oncogene, 2004-12, Vol.23 (57), p.9259-9268

2004

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Sep15, a Thioredoxin-like Selenoprotein, Is Involved in the Unfolded Protein Response and Differentially Regulated by Adaptive and Acute ER Stresses

Biochemistry (Easton), 2009-09, Vol.48 (35), p.8458-8465

2009

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Role of selenium-containing proteins in T-cell and macrophage function

Proceedings of the Nutrition Society, 2010-08, Vol.69 (3), p.300-310

2010

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Transepithelial Migration of Neutrophils in Response to Leukotriene B4 Is Mediated by a Reactive Oxygen Species-Extracellular Signal-Regulated Kinase-Linked Cascade

The Journal of immunology (1950), 2003-06, Vol.170 (12), p.6273-6279

2003

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Disruption of Thioredoxin Reductase 1 Protects Mice from Acute Acetaminophen-Induced Hepatotoxicity through Enhanced NRF2 Activity

Chemical research in toxicology, 2013-07, Vol.26 (7), p.1088-1096

2013

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Blockade of Airway Inflammation and Hyperresponsiveness by Inhibition of BLT2, a Low-Affinity Leukotriene B4 Receptor

American journal of respiratory cell and molecular biology, 2010-03, Vol.42 (3), p.294-303

2010

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High Error Rates in Selenocysteine Insertion in Mammalian Cells Treated with the Antibiotic Doxycycline, Chloramphenicol, or Geneticin

The Journal of biological chemistry, 2013-05, Vol.288 (21), p.14709-14715

2013

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Tumor Necrosis Factor-α Generates Reactive Oxygen Species via a Cytosolic Phospholipase A2-linked Cascade

The Journal of biological chemistry, 2000-10, Vol.275 (41), p.32357-32362

2000

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Simultaneous knockdown of the expression of two genes using multiple shRNAs and subsequent knock-in of their expression

Nature protocols, 2009-09, Vol.4 (9), p.1338-1348

2009

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Thioredoxin Reductase 1 Deficiency Reverses Tumor Phenotype and Tumorigenicity of Lung Carcinoma Cells

Delineating the role of glutathione peroxidase 4 in protecting cells against lipid hydroperoxide damage and in Alzheimer's disease

Biosynthesis of Selenocysteine, the 21st Amino Acid in the Genetic Code, and a Novel Pathway for Cysteine Biosynthesis

Thioredoxin reductase 1 protects against chemically induced hepatocarcinogenesis via control of cellular redox homeostasis

The 15kDa selenoprotein and thioredoxin reductase 1 promote colon cancer by different pathways

Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery

Targeting thioredoxin reductase 1 reduction in cancer cells inhibits self-sufficient growth and DNA replication

Knockout of the 15 kDa selenoprotein protects against chemically-induced aberrant crypt formation in mice

Abrogated thioredoxin system causes increased sensitivity to TNF-α-induced apoptosis via enrichment of p-ERK 1/2 in the nucleus

HIF-independent regulation of thioredoxin reductase 1 contributes to the high levels of reactive oxygen species induced by hypoxia

Deficiency in the 15-kDa selenoprotein inhibits tumorigenicity and metastasis of colon cancer cells

Thioredoxin reductase 1 deficiency enhances selenite toxicity in cancer cells via a thioredoxin-independent mechanism

Selenoproteins regulate macrophage invasiveness and extracellular matrix-related gene expression

Deficiency in the 15 kDa selenoprotein inhibits human colon cancer cell growth

Mouse models targeting selenocysteine tRNA expression for elucidating the role of selenoproteins in health and development

Selenoproteins that function in cancer prevention and promotion

Role of the BLT2, a leukotriene B4 receptor, in Ras transformation

Sep15, a Thioredoxin-like Selenoprotein, Is Involved in the Unfolded Protein Response and Differentially Regulated by Adaptive and Acute ER Stresses

Role of selenium-containing proteins in T-cell and macrophage function

Transepithelial Migration of Neutrophils in Response to Leukotriene B4 Is Mediated by a Reactive Oxygen Species-Extracellular Signal-Regulated Kinase-Linked Cascade

Disruption of Thioredoxin Reductase 1 Protects Mice from Acute Acetaminophen-Induced Hepatotoxicity through Enhanced NRF2 Activity

Blockade of Airway Inflammation and Hyperresponsiveness by Inhibition of BLT2, a Low-Affinity Leukotriene B4 Receptor

High Error Rates in Selenocysteine Insertion in Mammalian Cells Treated with the Antibiotic Doxycycline, Chloramphenicol, or Geneticin

Tumor Necrosis Factor-α Generates Reactive Oxygen Species via a Cytosolic Phospholipase A2-linked Cascade

Simultaneous knockdown of the expression of two genes using multiple shRNAs and subsequent knock-in of their expression

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