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Host Double Strand Break Repair Generates HIV-1 Strains Resistant to CRISPR/Cas9

Scientific reports, 2016-07, Vol.6 (1), p.29530-29530, Article 29530

2016

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DNA strand breaks and gaps target retroviral intasome binding and integration

Nature communications, 2023-11, Vol.14 (1), p.7072-15, Article 7072

2023

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Biotechnologies for Gene Therapy: RNA, CRISPR, Nanobots, and Preclinical Applications

1, 2022

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CRISPR/Cas9 Genome Editing to Disable the Latent HIV-1 Provirus

Frontiers in microbiology, 2018-12, Vol.9, p.3107-3107

2018

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CRISPR Genome Editing Applied to the Pathogenic Retrovirus HTLV-1

Frontiers in cellular and infection microbiology, 2020-12, Vol.10, p.580371

2020

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Retroviral intasomes search for a target DNA by 1D diffusion which rarely results in integration

Nature communications, 2016-04, Vol.7 (1), p.11409-11409, Article 11409

2016

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The base excision repair pathway is required for efficient lentivirus integration

PloS one, 2011-03, Vol.6 (3), p.e17862

2011

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Nucleosome DNA unwrapping does not affect prototype foamy virus integration efficiency or site selection

PloS one, 2019-03, Vol.14 (3), p.e0212764-e0212764

2019

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Expression and purification of nuclease-free protocatechuate 3,4-dioxygenase for prolonged single-molecule fluorescence imaging

Analytical biochemistry, 2018-09, Vol.556, p.78-84

2018

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Strategies for Targeting Retroviral Integration for Safer Gene Therapy: Advances and Challenges

Frontiers in molecular biosciences, 2021-05, Vol.8, p.662331-662331

2021

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Retroviral prototype foamy virus intasome binding to a nucleosome target does not determine integration efficiency

The Journal of biological chemistry, 2021-01, Vol.296, p.100550-100550, Article 100550

2021

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Repair of oxidative DNA base damage in the host genome influences the HIV integration site sequence preference

PloS one, 2014-07, Vol.9 (7), p.e103164-e103164

2014

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DNA Damage-Dependent Acetylation and Ubiquitination of H2AX Enhances Chromatin Dynamics

Molecular and Cellular Biology, 2007-10, Vol.27 (20), p.7028-7040

2007

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Prototype Foamy Virus Integrase Displays Unique Biochemical Activities among Retroviral Integrases

Biomolecules (Basel, Switzerland), 2021-12, Vol.11 (12), p.1910

2021

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Removal of nuclease contamination during purification of recombinant prototype foamy virus integrase

Journal of virological methods, 2016-09, Vol.235, p.134-138

2016

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Widespread nuclease contamination in commonly used oxygen-scavenging systems

Nature methods, 2015-10, Vol.12 (10), p.901-902

2015

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Expression and Purification of Nuclease-Free Oxygen Scavenger Protocatechuate 3,4-Dioxygenase

Journal of visualized experiments, 2019-11 (153)

2019

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Assembly and Purification of Prototype Foamy Virus Intasomes

Journal of visualized experiments, 2018-03 (133)

2018

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Prototype foamy virus intasome aggregation is mediated by outer protein domains and prevented by protocatechuic acid

Scientific reports, 2019-01, Vol.9 (1), p.132-132, Article 132

2019

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siRNA screening of a targeted library of DNA repair factors in HIV infection reveals a role for base excision repair in HIV integration

PloS one, 2011-03, Vol.6 (3), p.e17612-e17612

2011

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Detection and Removal of Nuclease Contamination During Purification of Recombinant Prototype Foamy Virus Integrase

Journal of visualized experiments, 2017-12 (130)

2017

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Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection

The EMBO journal, 2001-06, Vol.20 (12), p.3272-3281

2001

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The DNA Repair Genes XPB and XPD Defend Cells from Retroviral Infection

Proceedings of the National Academy of Sciences - PNAS, 2006-03, Vol.103 (12), p.4622-4627

2006

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Evidence that hMLH3 functions primarily in meiosis and in hMSH2-hMSH3 mismatch repair

Cancer biology & therapy, 2009-07, Vol.8 (14), p.1411-1420

2009

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Alterations of the Tumor Suppressor Gene Parkin in Non-Small Cell Lung Cancer

Clinical cancer research, 2004-04, Vol.10 (8), p.2720-2724

2004

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Host Double Strand Break Repair Generates HIV-1 Strains Resistant to CRISPR/Cas9

DNA strand breaks and gaps target retroviral intasome binding and integration

Biotechnologies for Gene Therapy: RNA, CRISPR, Nanobots, and Preclinical Applications

CRISPR/Cas9 Genome Editing to Disable the Latent HIV-1 Provirus

CRISPR Genome Editing Applied to the Pathogenic Retrovirus HTLV-1

Retroviral intasomes search for a target DNA by 1D diffusion which rarely results in integration

The base excision repair pathway is required for efficient lentivirus integration

Nucleosome DNA unwrapping does not affect prototype foamy virus integration efficiency or site selection

Expression and purification of nuclease-free protocatechuate 3,4-dioxygenase for prolonged single-molecule fluorescence imaging

Strategies for Targeting Retroviral Integration for Safer Gene Therapy: Advances and Challenges

Retroviral prototype foamy virus intasome binding to a nucleosome target does not determine integration efficiency

Repair of oxidative DNA base damage in the host genome influences the HIV integration site sequence preference

DNA Damage-Dependent Acetylation and Ubiquitination of H2AX Enhances Chromatin Dynamics

Prototype Foamy Virus Integrase Displays Unique Biochemical Activities among Retroviral Integrases

Removal of nuclease contamination during purification of recombinant prototype foamy virus integrase

Widespread nuclease contamination in commonly used oxygen-scavenging systems

Expression and Purification of Nuclease-Free Oxygen Scavenger Protocatechuate 3,4-Dioxygenase

Assembly and Purification of Prototype Foamy Virus Intasomes

Prototype foamy virus intasome aggregation is mediated by outer protein domains and prevented by protocatechuic acid

siRNA screening of a targeted library of DNA repair factors in HIV infection reveals a role for base excision repair in HIV integration

Detection and Removal of Nuclease Contamination During Purification of Recombinant Prototype Foamy Virus Integrase

Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection

The DNA Repair Genes XPB and XPD Defend Cells from Retroviral Infection

Evidence that hMLH3 functions primarily in meiosis and in hMSH2-hMSH3 mismatch repair

Alterations of the Tumor Suppressor Gene Parkin in Non-Small Cell Lung Cancer

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