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Angiogenic gene therapy in cardiovascular diseases: dream or vision?

European heart journal, 2017-05, Vol.38 (18), p.1365-1371

2017

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Gene Therapy of Critical Limb Ischemia Enters Clinical Use

Molecular therapy, 2019-12, Vol.27 (12), p.2053-2053

Ylä-Herttuala, Seppo

2019

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EphrinB2/EphB4 signaling regulates non‐sprouting angiogenesis by VEGF

EMBO reports, 2018-05, Vol.19 (5), p.n/a

2018

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Biology of vascular endothelial growth factors

FEBS letters, 2006-05, Vol.580 (12), p.2879-2887

2006

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Optimized Protocol for Accurate Titration of Adeno-Associated Virus Vectors

Human gene therapy, 2021-10, Vol.32 (19-20), p.1270-1279

2021

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Cardiac Lymphatics – A New Avenue for Therapeutics?

Trends in endocrinology and metabolism, 2017-04, Vol.28 (4), p.285-296

2017

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Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction

Scientific reports, 2018-11, Vol.8 (1), p.16709-13, Article 16709

2018

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Adenovirus-mediated gene therapy with sitimagene ceradenovec followed by intravenous ganciclovir for patients with operable high-grade glioma (ASPECT): a randomised, open-label, phase 3 trial

The lancet oncology, 2013-08, Vol.14 (9), p.823-833

2013

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History of gene therapy

Gene, 2013-08, Vol.525 (2), p.162-169

2013

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High expression of Tie-2 predicts poor prognosis in primary high grade serous ovarian cancer

PloS one, 2020-11, Vol.15 (11), p.e0241484-e0241484

2020

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Changes in nuclear and cytoplasmic microRNA distribution in response to hypoxic stress

Scientific reports, 2019-07, Vol.9 (1), p.10332-12, Article 10332

2019

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Expression profiles of VEGF-A, VEGF-D and VEGFR1 are higher in distant metastases than in matched primary high grade epithelial ovarian cancer

BMC cancer, 2019-06, Vol.19 (1), p.584-584, Article 584

2019

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Stabilization of HIF-1α is critical to improve wound healing in diabetic mice

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (49), p.19426-19431

2008

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The effect of intracoronary infusion of bone marrow-derived mononuclear cells on all-cause mortality in acute myocardial infarction: the BAMI trial

European heart journal, 2020-10, Vol.41 (38), p.3702-3710

2020

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Functional roles of the membrane-associated AAV protein MAAP

Scientific reports, 2021-11, Vol.11 (1), p.21698-21698, Article 21698

2021

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Baculovirus: an Insect-derived Vector for Diverse Gene Transfer Applications

Molecular therapy, 2013-04, Vol.21 (4), p.739-749

2013

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Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease

Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (38), p.16505-16510

2009

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Hyperbaric oxygen therapy activates hypoxia-inducible factor 1 (HIF-1), which contributes to improved wound healing in diabetic mice

Wound repair and regeneration, 2015-01, Vol.23 (1), p.98-103

2015

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Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth

Proceedings of the National Academy of Sciences - PNAS, 2008-05, Vol.105 (18), p.6620-6625

2008

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Promoting blood vessel growth in ischemic diseases: challenges in translating preclinical potential into clinical success

Disease models & mechanisms, 2013-03, Vol.6 (2), p.312-322

2013

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Adenoviral Gene Therapy Vectors in Clinical Use—Basic Aspects with a Special Reference to Replication-Competent Adenovirus Formation and Its Impact on Clinical Safety

International journal of molecular sciences, 2023-11, Vol.24 (22), p.16519

2023

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Lymphatic vessel insufficiency in hypercholesterolemic mice alters lipoprotein levels and promotes atherogenesis

Arteriosclerosis, thrombosis, and vascular biology, 2014-06, Vol.34 (6), p.1162-1170

2014

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Effects of Angiopoietin-2-Blocking Antibody on Endothelial Cell-Cell Junctions and Lung Metastasis

JNCI : Journal of the National Cancer Institute, 2012-03, Vol.104 (6), p.461-475

2012

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Epigenetic Regulation of Vascular Smooth Muscle Cell Phenotype Switching in Atherosclerotic Artery Remodeling: A Mini-Review

Frontiers in genetics, 2021-08, Vol.12, p.719456

2021

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Current Status of Cardiovascular Gene Therapy

Molecular therapy, 2007-07, Vol.15 (7), p.1233-1247

2007

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Angiogenic gene therapy in cardiovascular diseases: dream or vision?

Gene Therapy of Critical Limb Ischemia Enters Clinical Use

EphrinB2/EphB4 signaling regulates non‐sprouting angiogenesis by VEGF

Biology of vascular endothelial growth factors

Optimized Protocol for Accurate Titration of Adeno-Associated Virus Vectors

Cardiac Lymphatics – A New Avenue for Therapeutics?

Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction

Adenovirus-mediated gene therapy with sitimagene ceradenovec followed by intravenous ganciclovir for patients with operable high-grade glioma (ASPECT): a randomised, open-label, phase 3 trial

History of gene therapy

High expression of Tie-2 predicts poor prognosis in primary high grade serous ovarian cancer

Changes in nuclear and cytoplasmic microRNA distribution in response to hypoxic stress

Expression profiles of VEGF-A, VEGF-D and VEGFR1 are higher in distant metastases than in matched primary high grade epithelial ovarian cancer

Stabilization of HIF-1α is critical to improve wound healing in diabetic mice

The effect of intracoronary infusion of bone marrow-derived mononuclear cells on all-cause mortality in acute myocardial infarction: the BAMI trial

Functional roles of the membrane-associated AAV protein MAAP

Baculovirus: an Insect-derived Vector for Diverse Gene Transfer Applications

Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease

Hyperbaric oxygen therapy activates hypoxia-inducible factor 1 (HIF-1), which contributes to improved wound healing in diabetic mice

Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth

Promoting blood vessel growth in ischemic diseases: challenges in translating preclinical potential into clinical success

Adenoviral Gene Therapy Vectors in Clinical Use—Basic Aspects with a Special Reference to Replication-Competent Adenovirus Formation and Its Impact on Clinical Safety

Lymphatic vessel insufficiency in hypercholesterolemic mice alters lipoprotein levels and promotes atherogenesis

Effects of Angiopoietin-2-Blocking Antibody on Endothelial Cell-Cell Junctions and Lung Metastasis

Epigenetic Regulation of Vascular Smooth Muscle Cell Phenotype Switching in Atherosclerotic Artery Remodeling: A Mini-Review

Current Status of Cardiovascular Gene Therapy

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