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403 Tumor-infiltrating lymphocytes (TIL) with inducible and membrane-bound IL-12 exhibit superior antitumor activity in vitro

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A452-A452

2023

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Absorption, metabolism, and excretion of [14C]vildagliptin, a novel dipeptidyl peptidase 4 inhibitor, in humans

Drug metabolism and disposition, 2009-03, Vol.37 (3), p.536-544

2009

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Disposition of vildagliptin, a novel dipeptidyl peptidase 4 inhibitor, in rats and dogs

Drug metabolism and disposition, 2009-03, Vol.37 (3), p.545-554

2009

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IV-IVC considerations in the development of immediate-release oral dosage form

Journal of pharmaceutical sciences, 2005-07, Vol.94 (7), p.1396-1417

2005

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Dynamics of circulating cytokines and chemokines during and after tumor-infiltrating lymphocyte cell therapy with lifileucel in advanced melanoma patients

Journal of clinical oncology, 2024-06, Vol.42 (16_suppl), p.9594-9594

2024

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Abstract 25: Multimodal single-cell analysis of lifileucel tumor-infiltrating lymphocyte (TIL) product identifies additional high-resolution potential features

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.25-25

2024

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Structure−Function Relationships of Human Liver Cytochromes P450 3A: Aflatoxin B1 Metabolism as a Probe

Biochemistry (Easton), 1998-09, Vol.37 (36), p.12536-12545

1998

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Population pharmacokinetics–pharmacodynamics of oral everolimus in patients with seizures associated with tuberous sclerosis complex

Journal of pharmacokinetics and pharmacodynamics, 2018-10, Vol.45 (5), p.707-719

2018

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Clinical pharmacology assessment of PF-06647020 (PF-7020), an antibody-drug conjugate (ADC) targeting protein tyrosine kinase 7 (PTK7), in adult patients (pts) with advanced solid tumors

Journal of clinical oncology, 2018-05, Vol.36 (15_suppl), p.2574-2574

2018

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Methanol solvent may cause increased apparent metabolic instability in in vitro assays

Drug metabolism and disposition, 2001-02, Vol.29 (2), p.185

2001

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Single- and multiple-dose pharmacokinetics of inhaled indacaterol in healthy Chinese volunteers

European journal of drug metabolism and pharmacokinetics, 2015-06, Vol.40 (2), p.203-208

2015

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Mechanistic studies of uridine diphosphate glucuronosyltransferase

Chemico-biological interactions, 1994, Vol.90 (1), p.47-58

1994

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Cytochrome P450 2C11:Escherichia coliExpression, Purification, Functional Characterization, and Mechanism-Based Inactivation of the Enzyme

Archives of biochemistry and biophysics, 1997-02, Vol.338 (1), p.35-42

1997

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Metabolism of 1,2-Dichloro-1-fluoroethane and 1-Fluoro-1,2,2-trichloroethane: Electronic Factors Govern the Regioselectivity of Cytochrome P450-Dependent Oxidation

Chemical research in toxicology, 1996-01, Vol.9 (1), p.50-57

1996

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Slow-binding inhibition of carboxylesterase and other serine hydrolases by chlorodifluoroacetaldehyde

Chemical research in toxicology, 1993-09, Vol.6 (5), p.630-634

1993

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Identification of the Heme-Modified Peptides from Cumene Hydroperoxide-Inactivated Cytochrome P450 3A4

Biochemistry (Easton), 1998-12, Vol.37 (50), p.17448-17457

1998

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Designing Safer Chemicals: Predicting the Rates of Metabolism of Halogenated Alkanes

Proceedings of the National Academy of Sciences - PNAS, 1995-11, Vol.92 (24), p.11076-11080

1995

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Cytochrome P450 2C11: Escherichia coli expression, purification, functional characterization, and mechanism-based inactivation of the enzyme

Archives of biochemistry and biophysics, 1997-02, Vol.338 (1), p.35-42

1997

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Studies on the biotransformation and bioactivation of halogenated alkanes

Yin, Hequn

1995

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Application of computational chemistry in the study of biologically reactive intermediates

Advances in experimental medicine and biology, 1996, Vol.387, p.347

1996

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Metabolism of 1-Fluoro-1,1,2-trichloroethane, 1,2-Dichloro-1,1-difluoroethane, and 1,1,1-Trifluoro-2-chloroethane

Chemical research in toxicology, 1995-03, Vol.8 (2), p.262-268

1995

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Reaction of Trifluoroacetaldehyde with Amino Acids, Nucleotides, Lipid Nucleophiles, and Their Analogs

Chemical research in toxicology, 1996-01, Vol.9 (1), p.140-146

1996

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Single-microvessel occlusion produces lamina-specific microvascular flow vasodynamics and signs of neurodegenerative change

Cell reports (Cambridge), 2023-05, Vol.42 (5), p.112469-112469, Article 112469

2023

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Subdural neural interfaces for long-term electrical recording, optical microscopy and magnetic resonance imaging

Biomaterials, 2022-02, Vol.281, p.121352-121352, Article 121352

2022

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Large-depth three-photon fluorescence microscopy imaging of cortical microvasculature on nonhuman primates with bright AIE probe In vivo

Biomaterials, 2022-10, Vol.289, p.121809-121809, Article 121809

2022

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403 Tumor-infiltrating lymphocytes (TIL) with inducible and membrane-bound IL-12 exhibit superior antitumor activity in vitro

Absorption, metabolism, and excretion of [14C]vildagliptin, a novel dipeptidyl peptidase 4 inhibitor, in humans

Disposition of vildagliptin, a novel dipeptidyl peptidase 4 inhibitor, in rats and dogs

IV-IVC considerations in the development of immediate-release oral dosage form

Dynamics of circulating cytokines and chemokines during and after tumor-infiltrating lymphocyte cell therapy with lifileucel in advanced melanoma patients

Abstract 25: Multimodal single-cell analysis of lifileucel tumor-infiltrating lymphocyte (TIL) product identifies additional high-resolution potential features

Structure−Function Relationships of Human Liver Cytochromes P450 3A: Aflatoxin B1 Metabolism as a Probe

Population pharmacokinetics–pharmacodynamics of oral everolimus in patients with seizures associated with tuberous sclerosis complex

Clinical pharmacology assessment of PF-06647020 (PF-7020), an antibody-drug conjugate (ADC) targeting protein tyrosine kinase 7 (PTK7), in adult patients (pts) with advanced solid tumors

Methanol solvent may cause increased apparent metabolic instability in in vitro assays

Single- and multiple-dose pharmacokinetics of inhaled indacaterol in healthy Chinese volunteers

Mechanistic studies of uridine diphosphate glucuronosyltransferase

Cytochrome P450 2C11:Escherichia coliExpression, Purification, Functional Characterization, and Mechanism-Based Inactivation of the Enzyme

Metabolism of 1,2-Dichloro-1-fluoroethane and 1-Fluoro-1,2,2-trichloroethane: Electronic Factors Govern the Regioselectivity of Cytochrome P450-Dependent Oxidation

Slow-binding inhibition of carboxylesterase and other serine hydrolases by chlorodifluoroacetaldehyde

Identification of the Heme-Modified Peptides from Cumene Hydroperoxide-Inactivated Cytochrome P450 3A4

Designing Safer Chemicals: Predicting the Rates of Metabolism of Halogenated Alkanes

Cytochrome P450 2C11: Escherichia coli expression, purification, functional characterization, and mechanism-based inactivation of the enzyme

Studies on the biotransformation and bioactivation of halogenated alkanes

Application of computational chemistry in the study of biologically reactive intermediates

Metabolism of 1-Fluoro-1,1,2-trichloroethane, 1,2-Dichloro-1,1-difluoroethane, and 1,1,1-Trifluoro-2-chloroethane

Reaction of Trifluoroacetaldehyde with Amino Acids, Nucleotides, Lipid Nucleophiles, and Their Analogs

Single-microvessel occlusion produces lamina-specific microvascular flow vasodynamics and signs of neurodegenerative change

Subdural neural interfaces for long-term electrical recording, optical microscopy and magnetic resonance imaging

Large-depth three-photon fluorescence microscopy imaging of cortical microvasculature on nonhuman primates with bright AIE probe In vivo

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