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Optimizing EphA2-CAR T Cells for the Adoptive Immunotherapy of Glioma

Molecular therapy. Methods & clinical development, 2018-06, Vol.9, p.70-80

2018

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T cells redirected against CD70 for the immunotherapy of CD70-positive malignancies

Blood, 2011-04, Vol.117 (16), p.4304-4314

2011

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263 Unveiling the role of macrophages in CAR T-cell induced remodeling of the brain tumor immune microenvironment: implications for anti-glioma adoptive immunotherapy

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A303-A303

2023

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IMMU-05. TARGETING THE DYSREGULATED DNA METHYLOME DURING CAR T CELL MANUFACTURING IMPROVES THEIR FITNESS IN IMMUNOCOMPETENT BRAIN TUMOR MODELS

Neuro-oncology (Charlottesville, Va.), 2024-06, Vol.26 (Suppl 4), p.0-0

2024

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Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Rα2-CAR T Cells but Results in Antigen Loss Variants

Cancer immunology research, 2017-07, Vol.5 (7), p.571-581

2017

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Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity

Science translational medicine, 2021-11, Vol.13 (620), p.eabh0272

2021

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Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells

Cancer discovery, 2017-11, Vol.7 (11), p.1238-1247

2017

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IMMU-05. B7-H3-SPECIFIC CAR T CELLS HAVE POTENT ANTI-TUMOR ACTIVITY IN THE GL261 IMMUNE-COMPETENT MURINE BRAIN TUMOR MODEL

Neuro-oncology (Charlottesville, Va.), 2020-12, Vol.22 (Supplement_3), p.iii360-iii360

2020

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IMMU-06. CAR DESIGN SHAPES THE BRAIN TUMOR IMMUNE MICROENVIRONMENT: IMPACT ON ACTIVITY AND PERSISTENCE OF ANTI-GLIOMA ADOPTIVE T CELL IMMUNOTHERAPY

Neuro-oncology (Charlottesville, Va.), 2024-06, Vol.26 (Suppl 4), p.0-0

2024

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Cell-surface antigen profiling of pediatric brain tumors: B7-H3 is consistently expressed and can be targeted via local or systemic CAR T-cell delivery

Neuro-oncology (Charlottesville, Va.), 2021-06, Vol.23 (6), p.999-1011

2021

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IMMU-01. Combining CD28 and 4-1BB costimulation in trans enhances the anti-glioma efficacy and persistence of B7-H3 CAR T cells in immune-competent brain tumor models

Neuro-oncology (Charlottesville, Va.), 2022-06, Vol.24 (Supplement_1), p.i80-i81

2022

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IMMU-01. Combining CD28 and 4-1BB costimulationin trans enhances the anti-glioma efficacy and persistence of B7-H3 CAR T cells in immune-competent brain tumor models

Neuro-oncology (Charlottesville, Va.), 2022-06, Vol.24 (Suppl 1), p.i80-i81

2022

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T Cells Redirected to EphA2 for the Immunotherapy of Glioblastoma

Molecular therapy, 2013-03, Vol.21 (3), p.629-637

2013

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HBsAg-redirected T cells exhibit antiviral activity in HBV-infected human liver chimeric mice

Cytotherapy (Oxford, England), 2018-05, Vol.20 (5), p.697-705

2018

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EXTH-20. SYNGENEIC B7-H3-SPECIFIC CAR T-CELLS HAVE POTENT ANTI-BRAIN TUMOR ACTIVITY VIA LOCAL OR SYSTEMIC DELIVERY

Neuro-oncology (Charlottesville, Va.), 2020-11, Vol.22 (Supplement_2), p.ii91-ii91

2020

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IMMU-01. EVALUATING THE IMPACT OF CAR DESIGN ON THE TUMOR IMMUNE MICROENVIRONMENT AND ANTI-TUMOR RESPONSE IN SYNGENEIC GLIOMA MODELS

Neuro-oncology (Charlottesville, Va.), 2023-06, Vol.25 (Supplement_1), p.i49-i49

2023

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IMMU-20. SELECTING AN EPHA2-CAR FOR THE IMMUNOTHERAPY OF DIPG AND GBM

Neuro-oncology (Charlottesville, Va.), 2017-06, Vol.19 (suppl_4), p.iv32-iv32

2017

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De novo DNA methylation programs regulate CAR T-cell exhaustion

The Journal of immunology (1950), 2020-05, Vol.204 (1_Supplement), p.246-246.5

2020

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IMMU-17. TRANSGENIC EXPRESSION OF IL15 IMPROVES ANTIGLIOMA ACTIVITY OF IL13RΑ2-CAR T CELLS

Neuro-oncology (Charlottesville, Va.), 2017-06, Vol.19 (suppl_4), p.iv31-iv31

2017

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GRP78-CAR T cell effector function against solid and brain tumors is controlled by GRP78 expression on T cells

Cell reports. Medicine, 2023-11, Vol.4 (11), p.101297, Article 101297

2023

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Abstract LB-147: Administration of HER2-CAR T cells after lymphodepletion safely improves T cell expansion and induces clinical responses in patients with advanced sarcomas

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.LB-147-LB-147

2019

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Wear performance of tetrahedral amorphous carbon films prepared by filtered cathodic vacuum arc technique

Surface & coatings technology, 2002-12, Vol.161 (2), p.120-124

2002

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Autologous HER2 CMV bispecific CAR T cells are safe and demonstrate clinical benefit for glioblastoma in a Phase I trial

Journal for immunotherapy of cancer, 2015-11, Vol.3 (Suppl 2), p.O11-O11, Article O11

2015

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CAR T-cell Design-dependent Remodeling of the Brain Tumor Immune Microenvironment Modulates Tumor-associated Macrophages and Anti-glioma Activity

Cancer research communications, 2023-12, Vol.3 (12), p.2430-2446

2023

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Optimizing EphA2-CAR T Cells for the Adoptive Immunotherapy of Glioma

T cells redirected against CD70 for the immunotherapy of CD70-positive malignancies

263 Unveiling the role of macrophages in CAR T-cell induced remodeling of the brain tumor immune microenvironment: implications for anti-glioma adoptive immunotherapy

IMMU-05. TARGETING THE DYSREGULATED DNA METHYLOME DURING CAR T CELL MANUFACTURING IMPROVES THEIR FITNESS IN IMMUNOCOMPETENT BRAIN TUMOR MODELS

Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Rα2-CAR T Cells but Results in Antigen Loss Variants

Deleting DNMT3A in CAR T cells prevents exhaustion and enhances antitumor activity

Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells

IMMU-05. B7-H3-SPECIFIC CAR T CELLS HAVE POTENT ANTI-TUMOR ACTIVITY IN THE GL261 IMMUNE-COMPETENT MURINE BRAIN TUMOR MODEL

HER2-Specific Chimeric Antigen Receptor-Modified Virus-Specific T Cells for Progressive Glioblastoma: A Phase 1 Dose-Escalation Trial

IMMU-06. CAR DESIGN SHAPES THE BRAIN TUMOR IMMUNE MICROENVIRONMENT: IMPACT ON ACTIVITY AND PERSISTENCE OF ANTI-GLIOMA ADOPTIVE T CELL IMMUNOTHERAPY

Cell-surface antigen profiling of pediatric brain tumors: B7-H3 is consistently expressed and can be targeted via local or systemic CAR T-cell delivery

IMMU-01. Combining CD28 and 4-1BB costimulation in trans enhances the anti-glioma efficacy and persistence of B7-H3 CAR T cells in immune-competent brain tumor models

IMMU-01. Combining CD28 and 4-1BB costimulationin trans enhances the anti-glioma efficacy and persistence of B7-H3 CAR T cells in immune-competent brain tumor models

T Cells Redirected to EphA2 for the Immunotherapy of Glioblastoma

HBsAg-redirected T cells exhibit antiviral activity in HBV-infected human liver chimeric mice

EXTH-20. SYNGENEIC B7-H3-SPECIFIC CAR T-CELLS HAVE POTENT ANTI-BRAIN TUMOR ACTIVITY VIA LOCAL OR SYSTEMIC DELIVERY

IMMU-01. EVALUATING THE IMPACT OF CAR DESIGN ON THE TUMOR IMMUNE MICROENVIRONMENT AND ANTI-TUMOR RESPONSE IN SYNGENEIC GLIOMA MODELS

IMMU-20. SELECTING AN EPHA2-CAR FOR THE IMMUNOTHERAPY OF DIPG AND GBM

De novo DNA methylation programs regulate CAR T-cell exhaustion

IMMU-17. TRANSGENIC EXPRESSION OF IL15 IMPROVES ANTIGLIOMA ACTIVITY OF IL13RΑ2-CAR T CELLS

GRP78-CAR T cell effector function against solid and brain tumors is controlled by GRP78 expression on T cells

Abstract LB-147: Administration of HER2-CAR T cells after lymphodepletion safely improves T cell expansion and induces clinical responses in patients with advanced sarcomas

Wear performance of tetrahedral amorphous carbon films prepared by filtered cathodic vacuum arc technique

Autologous HER2 CMV bispecific CAR T cells are safe and demonstrate clinical benefit for glioblastoma in a Phase I trial

CAR T-cell Design-dependent Remodeling of the Brain Tumor Immune Microenvironment Modulates Tumor-associated Macrophages and Anti-glioma Activity

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