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Identification of Shp-2 as a Stat5A Phosphatase

The Journal of biological chemistry, 2003-05, Vol.278 (19), p.16520-16527

2003

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JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

Cell, 1993-07, Vol.74 (2), p.227-236

1993

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Disabled-2 (Dab2) is an SH3 domain-binding partner of Grb2

Oncogene, 1998-03, Vol.16 (12), p.1561-1569

1998

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Protein-tyrosine Phosphatase Shp-1 Is a Negative Regulator of IL-4- and IL-13-dependent Signal Transduction

The Journal of biological chemistry, 1998-12, Vol.273 (51), p.33893-33896

1998

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Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene

Cell, 1993-07, Vol.73 (7), p.1445-1454

1993

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Structure of the Murine Jak2 Protein-Tyrosine Kinase and its Role in Interleukin 3 Signal Transduction

Proceedings of the National Academy of Sciences - PNAS, 1993-09, Vol.90 (18), p.8429-8433

1993

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SHP-1 regulates Fcγ receptor–mediated phagocytosis and the activation of RAC

Blood, 2002-09, Vol.100 (5), p.1852-1859

2002

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A Novel Phosphotyrosine Motif with a Critical Amino Acid at Position −2 for the SH2 Domain-mediated Activation of the Tyrosine Phosphatase SHP-1

The Journal of biological chemistry, 1997-05, Vol.272 (20), p.13066-13072

1997

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Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor beta chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis

Molecular and Cellular Biology, 1993-12, Vol.13 (12), p.7577-7586

1993

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Protein tyrosine phosphatase containing SH2 domains: characterization, preferential expression in hematopoietic cells, and localization to human chromosome 12p12-p13

Molecular and Cellular Biology, 1992-02, Vol.12 (2), p.836-846

1992

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Efficacy of ssg and SSG/IFNα2 against human prostate cancer xenograft tumors in mice : a role for direct growth inhibition in SSG anti-tumor action

Cancer chemotherapy and pharmacology, 2007-08, Vol.60 (3), p.341-349

2007

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SLP-76 Is a Direct Substrate of SHP-1 Recruited to Killer Cell Inhibitory Receptors

The Journal of biological chemistry, 1998-10, Vol.273 (42), p.27518-27523

1998

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Engagement of Gab1 and Gab2 in Erythropoietin Signaling

The Journal of biological chemistry, 1999-08, Vol.274 (35), p.24469-24474

1999

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Recruitment of SH2-Containing Protein Tyrosine Phosphatase SHP-1 to the Interleukin 2 Receptor; Loss of SHP-1 Expression in Human T-Lymphotropic Virus Type I-Transformed T Cells

Proceedings of the National Academy of Sciences - PNAS, 1998-03, Vol.95 (7), p.3845-3850

1998

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Novel SHP-1 inhibitors tyrosine phosphatase inhibitor-1 and analogs with preclinical anti-tumor activities as tolerated oral agents

The Journal of immunology (1950), 2010-06, Vol.184 (11), p.6529-6536

2010

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Phosphorylation of Tyrosine 503 in the Erythropoietin Receptor (EpR) Is Essential for Binding the P85 Subunit of Phosphatidylinositol (PI) 3-Kinase and for EpR-associated PI 3-Kinase Activity (∗)

The Journal of biological chemistry, 1995-10, Vol.270 (40), p.23402-23408

1995

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Cells previously desensitized to type 1 interferons display different mechanisms of activation of stat-dependent gene expression from naïve cells

The Journal of biological chemistry, 2004-01, Vol.279 (5), p.3245-3253

2004

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Deficiency of SHP-1 Protein-Tyrosine Phosphatase Activity Results in Heightened Osteoclast Function and Decreased Bone Density

The American journal of pathology, 1999-07, Vol.155 (1), p.223-233

1999

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The role and target potential of protein tyrosine phosphatases in cancer

Current oncology reports, 2008-03, Vol.10 (2), p.114-121

2008

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Association of the Interferon-dependent Tyrosine Kinase Tyk-2 with the Hematopoietic Cell Phosphatase

The Journal of biological chemistry, 1995-08, Vol.270 (31), p.18179-18182

1995

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Abstract 868: Oral SHP-1 inhibitor TPI-1a4 increases TILs in melanoma tumors and interacts positively with CTLA4 antibody for melanoma cure in mice

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.868-868

2012

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Sodium Stibogluconate Is a Potent Inhibitor of Protein Tyrosine Phosphatases and Augments Cytokine Responses in Hemopoietic Cell Lines

The Journal of immunology (1950), 2001-09, Vol.167 (6), p.3391-3397

2001

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Hematopoietic cells express two forms of lyn kinase differing by 21 amino acids in the amino terminus

Molecular and Cellular Biology, 1991-05, Vol.11 (5), p.2391-2398

1991

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Expression of a novel form of Tec kinase in hematopoietic cells and mapping of the gene to chromosome 5 near Kit

Oncogene, 1993-02, Vol.8 (2), p.417-424

1993

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PRL-2 increases Epo and IL-3 responses in hematopoietic cells

Blood cells, molecules, & diseases, 2010-04, Vol.44 (4), p.209-214

2010

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Identification of Shp-2 as a Stat5A Phosphatase

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

Disabled-2 (Dab2) is an SH3 domain-binding partner of Grb2

Protein-tyrosine Phosphatase Shp-1 Is a Negative Regulator of IL-4- and IL-13-dependent Signal Transduction

Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene

Structure of the Murine Jak2 Protein-Tyrosine Kinase and its Role in Interleukin 3 Signal Transduction

SHP-1 regulates Fcγ receptor–mediated phagocytosis and the activation of RAC

A Novel Phosphotyrosine Motif with a Critical Amino Acid at Position −2 for the SH2 Domain-mediated Activation of the Tyrosine Phosphatase SHP-1

Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor beta chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis

Protein tyrosine phosphatase containing SH2 domains: characterization, preferential expression in hematopoietic cells, and localization to human chromosome 12p12-p13

Efficacy of ssg and SSG/IFNα2 against human prostate cancer xenograft tumors in mice : a role for direct growth inhibition in SSG anti-tumor action

SLP-76 Is a Direct Substrate of SHP-1 Recruited to Killer Cell Inhibitory Receptors

Engagement of Gab1 and Gab2 in Erythropoietin Signaling

Recruitment of SH2-Containing Protein Tyrosine Phosphatase SHP-1 to the Interleukin 2 Receptor; Loss of SHP-1 Expression in Human T-Lymphotropic Virus Type I-Transformed T Cells

Novel SHP-1 inhibitors tyrosine phosphatase inhibitor-1 and analogs with preclinical anti-tumor activities as tolerated oral agents

Phosphorylation of Tyrosine 503 in the Erythropoietin Receptor (EpR) Is Essential for Binding the P85 Subunit of Phosphatidylinositol (PI) 3-Kinase and for EpR-associated PI 3-Kinase Activity (∗)

Cells previously desensitized to type 1 interferons display different mechanisms of activation of stat-dependent gene expression from naïve cells

Deficiency of SHP-1 Protein-Tyrosine Phosphatase Activity Results in Heightened Osteoclast Function and Decreased Bone Density

The role and target potential of protein tyrosine phosphatases in cancer

Association of the Interferon-dependent Tyrosine Kinase Tyk-2 with the Hematopoietic Cell Phosphatase

Abstract 868: Oral SHP-1 inhibitor TPI-1a4 increases TILs in melanoma tumors and interacts positively with CTLA4 antibody for melanoma cure in mice

Sodium Stibogluconate Is a Potent Inhibitor of Protein Tyrosine Phosphatases and Augments Cytokine Responses in Hemopoietic Cell Lines

Hematopoietic cells express two forms of lyn kinase differing by 21 amino acids in the amino terminus

Expression of a novel form of Tec kinase in hematopoietic cells and mapping of the gene to chromosome 5 near Kit

PRL-2 increases Epo and IL-3 responses in hematopoietic cells

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