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First‐in‐Human, Healthy Volunteers Integrated Protocol of ETC‐206, an Oral Mnk 1/2 Kinase Inhibitor Oncology Drug

Clinical and translational science, 2020-01, Vol.13 (1), p.57-66

2020

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In Vitro Phase I Cytochrome P450 Metabolism, Permeability and Pharmacokinetics of SB639, a Novel Histone Deacetylase Inhibitor in Preclinical Species

Biological and Pharmaceutical Bulletin, 2007, Vol.30(5), pp.1021-1024

2007

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Preclinical Metabolism and Pharmacokinetics of SB1317 (TG02), a Potent CDK/JAK2/FLT3 Inhibitor

Drug metabolism letters, 2012-05, Vol.6 (1), p.33-42

2012

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Development and validation of high-performance liquid chromatography-tandem mass spectrometry assay for 6-(3-benzoyl-ureido)-hexanoic acid hydroxyamide, a novel HDAC inhibitor, in mouse plasma for pharmacokinetic studies

Biomedical chromatography, 2007-02, Vol.21 (2), p.184-189

2007

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Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine: Results from a double-blinded, randomized Phase I clinical trial in healthy Asian volunteers

Vaccine, 2014-09, Vol.32 (39), p.5041-5048

2014

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SB939, a novel potent and orally active histone deacetylase inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer

Molecular cancer therapeutics, 2010-03, Vol.9 (3), p.642-652

2010

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Discovery of (2E)-3-{2-Butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl}-N-hydroxyacrylamide (SB939), an Orally Active Histone Deacetylase Inhibitor with a Superior Preclinical Profile

Journal of medicinal chemistry, 2011-07, Vol.54 (13), p.4694-4720

2011

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First-in-human phase 1 study of ETC-159 an oral PORCN inhbitor in patients with advanced solid tumours

Journal of clinical oncology, 2017-05, Vol.35 (15_suppl), p.2584-2584

2017

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Kinetics and Equilibria of the Formation and Reduction of the Disulfide Bonds in Arginine-Vasopressin and Oxytocin by Thiol/Disulfide Interchange with Glutathione and Cysteine

Journal of organic chemistry, 1994-07, Vol.59 (15), p.4223-4229

1994

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Preclinical metabolism and disposition of SB939 (Pracinostat), an orally active histone deacetylase inhibitor, and prediction of human pharmacokinetics

Drug metabolism and disposition, 2011-12, Vol.39 (12), p.2219-2232

2011

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Characterization of the thiol/disulfide chemistry of neurohypophyseal peptide hormones by high-performance liquid chromatography

Analytical chemistry (Washington), 1993-11, Vol.65 (21), p.3061-3066

1993

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Pharmacokinetic and Pharmacodynamic Properties of SB1317, a Potent and Orally Active Multi-Kinase Inhibitor

Blood, 2007-11, Vol.110 (11), p.4201-4201

2007

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Preclinical metabolism and pharmacokinetics of SB1317 (TG02), a potent CDK/JAK2/FLT3 inhibitor

Drug metabolism letters, 2012-03, Vol.6 (1), p.33

2012

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Thiol/Disulfide Exchange Reactions of Captopril and Penicillamine with Arginine Vasopressin and Oxytocin

Bioorganic chemistry, 1995-06, Vol.23 (2), p.109-118

1995

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Shoulder recovery for head and neck cancer patients after unilateral neck dissection: a pilot exploratory study

Journal of Novel Physiotherapy and Rehabilitation, 2022-09, Vol.6 (2), p.11-17

2022

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Oxidation/reduction chemistry of thiol groups in biological molecules

Journal of inorganic biochemistry, 1993-07, Vol.51 (1-2), p.27-27

1993

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A Micro-Sample Cup for Near-Infrared Analysis

Applied spectroscopy, 1988-08, Vol.42 (6), p.1128-1131

1988

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Out of Borneo: Neogene diversification of Sundaic freshwater crabs (Crustacea: Brachyura: Gecarcinucidae: Parathelphusa)

Journal of biogeography, 2013-01, Vol.40 (1), p.63-74

2013

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LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets

Nucleic acids research, 2012-12, Vol.40 (22), p.11189-11201

2012

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Return to work after spinal cord injury: a Singaporean pilot community-based rehabilitation program

Spinal cord, 2020-10, Vol.58 (10), p.1096-1103

2020

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Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humans

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (35), p.14468-14473

2013

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Effects of exposure to intermittent versus continuous red light on human circadian rhythms, melatonin suppression, and pupillary constriction

PloS one, 2014-05, Vol.9 (5), p.e96532-e96532

2014

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Fast three-dimensional micropatterning of PC12 cells in rapidly crosslinked hydrogel scaffolds using ultrasonic standing waves

Biofabrication, 2019-12, Vol.12 (1), p.015013-015013

2019

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Heart rate variability can be used to estimate sleepiness-related decrements in psychomotor vigilance during total sleep deprivation

Sleep (New York, N.Y.), 2012-03, Vol.35 (3), p.325-334

2012

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First‐in‐Human, Healthy Volunteers Integrated Protocol of ETC‐206, an Oral Mnk 1/2 Kinase Inhibitor Oncology Drug

First-in-Class Pan Caspase Inhibitor Developed for the Treatment of Liver Disease

In Vitro Phase I Cytochrome P450 Metabolism, Permeability and Pharmacokinetics of SB639, a Novel Histone Deacetylase Inhibitor in Preclinical Species

Preclinical Metabolism and Pharmacokinetics of SB1317 (TG02), a Potent CDK/JAK2/FLT3 Inhibitor

Development and validation of high-performance liquid chromatography-tandem mass spectrometry assay for 6-(3-benzoyl-ureido)-hexanoic acid hydroxyamide, a novel HDAC inhibitor, in mouse plasma for pharmacokinetic studies

Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine: Results from a double-blinded, randomized Phase I clinical trial in healthy Asian volunteers

SB939, a novel potent and orally active histone deacetylase inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer

Discovery of (2E)-3-{2-Butyl-1-[2-(diethylamino)ethyl]-1H-benzimidazol-5-yl}-N-hydroxyacrylamide (SB939), an Orally Active Histone Deacetylase Inhibitor with a Superior Preclinical Profile

First-in-human phase 1 study of ETC-159 an oral PORCN inhbitor in patients with advanced solid tumours

Kinetics and Equilibria of the Formation and Reduction of the Disulfide Bonds in Arginine-Vasopressin and Oxytocin by Thiol/Disulfide Interchange with Glutathione and Cysteine

Preclinical metabolism and disposition of SB939 (Pracinostat), an orally active histone deacetylase inhibitor, and prediction of human pharmacokinetics

Characterization of the thiol/disulfide chemistry of neurohypophyseal peptide hormones by high-performance liquid chromatography

Pharmacokinetic and Pharmacodynamic Properties of SB1317, a Potent and Orally Active Multi-Kinase Inhibitor

Preclinical metabolism and pharmacokinetics of SB1317 (TG02), a potent CDK/JAK2/FLT3 inhibitor

Thiol/Disulfide Exchange Reactions of Captopril and Penicillamine with Arginine Vasopressin and Oxytocin

Shoulder recovery for head and neck cancer patients after unilateral neck dissection: a pilot exploratory study

Oxidation/reduction chemistry of thiol groups in biological molecules

A Micro-Sample Cup for Near-Infrared Analysis

Out of Borneo: Neogene diversification of Sundaic freshwater crabs (Crustacea: Brachyura: Gecarcinucidae: Parathelphusa)

LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets

Return to work after spinal cord injury: a Singaporean pilot community-based rehabilitation program

Extensive diversity in circadian regulation of plasma lipids and evidence for different circadian metabolic phenotypes in humans

Effects of exposure to intermittent versus continuous red light on human circadian rhythms, melatonin suppression, and pupillary constriction

Fast three-dimensional micropatterning of PC12 cells in rapidly crosslinked hydrogel scaffolds using ultrasonic standing waves

Heart rate variability can be used to estimate sleepiness-related decrements in psychomotor vigilance during total sleep deprivation

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