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Adenosine Metabolism: Emerging Concepts for Cancer Therapy

Cancer cell, 2019-12, Vol.36 (6), p.582-596

2019

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Enzymes involved in metabolism of extracellular nucleotides and nucleosides: Functional implications and measurement of activities

Critical reviews in biochemistry and molecular biology, 2014-11, Vol.49 (6), p.473-497

Yegutkin, Gennady G.

2014

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Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors

Nature (London), 2014-12, Vol.516 (7531), p.395-399

2014

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CD73 facilitates EMT progression and promotes lung metastases in triple-negative breast cancer

Scientific reports, 2021-03, Vol.11 (1), p.6035-6035, Article 6035

2021

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Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade

Biochimica et biophysica acta, 2008-05, Vol.1783 (5), p.673-694

Yegutkin, Gennady G.

2008

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ATP and Adenosine Metabolism in Cancer: Exploitation for Therapeutic Gain

Pharmacological reviews, 2022-07, Vol.74 (3), p.797-824

2022

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The effect of intravenous interferon-beta-1a (FP-1201) on lung CD73 expression and on acute respiratory distress syndrome mortality: an open-label study

The lancet respiratory medicine, 2014-02, Vol.2 (2), p.98-107

2014

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Adenosine metabolism in the vascular system

Biochemical pharmacology, 2021-05, Vol.187, p.114373-114373, Article 114373

Yegutkin, Gennady G.

2021

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Beneficial Role of Erythrocyte Adenosine A2B Receptor–Mediated AMP-Activated Protein Kinase Activation in High-Altitude Hypoxia

Circulation (New York, N.Y.), 2016-08, Vol.134 (5), p.405-421

2016

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Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent

Nature communications, 2017-02, Vol.8 (1), p.14108-14108, Article 14108

2017

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ATP release, generation and hydrolysis in exocrine pancreatic duct cells

Purinergic signalling, 2015-12, Vol.11 (4), p.533-550

2015

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Altered purinergic signaling in CD73‐deficient mice inhibits tumor progression

European journal of immunology, 2011-05, Vol.41 (5), p.1231-1241

2011

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CD73 is a major regulator of adenosinergic signalling in mouse brain

PloS one, 2013-06, Vol.8 (6), p.e66896-e66896

2013

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Soluble and membrane-bound adenylate kinase and nucleotidases augment ATP-mediated inflammation in diabetic retinopathy eyes with vitreous hemorrhage

Journal of molecular medicine (Berlin, Germany), 2019-03, Vol.97 (3), p.341-354

2019

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Extracellular ATP Limits Homeostatic T Cell Migration Within Lymph Nodes

Frontiers in immunology, 2021-12, Vol.12, p.786595-786595

2021

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Enzyme-coupled assays for simultaneous detection of nanomolar ATP, ADP, AMP, adenosine, inosine and pyrophosphate concentrations in extracellular fluids

Biochimica et biophysica acta, 2012-10, Vol.1823 (10), p.1967-1975

2012

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Fully human anti-CD39 antibody potently inhibits ATPase activity in cancer cells via uncompetitive allosteric mechanism

mAbs, 2020-01, Vol.12 (1), p.1838036-1838036

2020

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MicroRNA‐155 modulates P2R signaling and Th2 priming of dendritic cells during allergic airway inflammation in mice

Allergy (Copenhagen), 2015-09, Vol.70 (9), p.1121-1129

2015

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Different role of CD73 in leukocyte trafficking via blood and lymph vessels

Blood, 2011-04, Vol.117 (16), p.4387-4393

2011

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Primary Amine Oxidase of Escherichia coli Is a Metabolic Enzyme that Can Use a Human Leukocyte Molecule as a Substrate

PloS one, 2015-11, Vol.10 (11), p.e0142367-e0142367

2015

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Nucleotide homeostasis and purinergic nociceptive signaling in rat meninges in migraine-like conditions

Purinergic signalling, 2016-09, Vol.12 (3), p.561-574

2016

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Absence of the Endothelial Oxidase AOC3 Leads to Abnormal Leukocyte Traffic In Vivo

Immunity (Cambridge, Mass.), 2005, Vol.22 (1), p.105-115

2005

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IFN-β protects from vascular leakage via up-regulation of CD73

European journal of immunology, 2007-12, Vol.37 (12), p.3334-3338

2007

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Extracellular ATP formation on vascular endothelial cells is mediated by ecto‐nucleotide kinase activities via phosphotransfer reactions

The FASEB journal, 2001-01, Vol.15 (1), p.251-260

2001

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Compartmentalization of adenosine metabolism in cancer cells and its modulation during acute hypoxia

Journal of cell science, 2020-05, Vol.133 (10)

2020

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Adenosine Metabolism: Emerging Concepts for Cancer Therapy

Enzymes involved in metabolism of extracellular nucleotides and nucleosides: Functional implications and measurement of activities

Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors

CD73 facilitates EMT progression and promotes lung metastases in triple-negative breast cancer

Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade

ATP and Adenosine Metabolism in Cancer: Exploitation for Therapeutic Gain

The effect of intravenous interferon-beta-1a (FP-1201) on lung CD73 expression and on acute respiratory distress syndrome mortality: an open-label study

Adenosine metabolism in the vascular system

Beneficial Role of Erythrocyte Adenosine A2B Receptor–Mediated AMP-Activated Protein Kinase Activation in High-Altitude Hypoxia

Erythrocytes retain hypoxic adenosine response for faster acclimatization upon re-ascent

ATP release, generation and hydrolysis in exocrine pancreatic duct cells

Altered purinergic signaling in CD73‐deficient mice inhibits tumor progression

CD73 is a major regulator of adenosinergic signalling in mouse brain

Soluble and membrane-bound adenylate kinase and nucleotidases augment ATP-mediated inflammation in diabetic retinopathy eyes with vitreous hemorrhage

Extracellular ATP Limits Homeostatic T Cell Migration Within Lymph Nodes

Enzyme-coupled assays for simultaneous detection of nanomolar ATP, ADP, AMP, adenosine, inosine and pyrophosphate concentrations in extracellular fluids

Fully human anti-CD39 antibody potently inhibits ATPase activity in cancer cells via uncompetitive allosteric mechanism

MicroRNA‐155 modulates P2R signaling and Th2 priming of dendritic cells during allergic airway inflammation in mice

Different role of CD73 in leukocyte trafficking via blood and lymph vessels

Primary Amine Oxidase of Escherichia coli Is a Metabolic Enzyme that Can Use a Human Leukocyte Molecule as a Substrate

Nucleotide homeostasis and purinergic nociceptive signaling in rat meninges in migraine-like conditions

Absence of the Endothelial Oxidase AOC3 Leads to Abnormal Leukocyte Traffic In Vivo

IFN-β protects from vascular leakage via up-regulation of CD73

Extracellular ATP formation on vascular endothelial cells is mediated by ecto‐nucleotide kinase activities via phosphotransfer reactions

Compartmentalization of adenosine metabolism in cancer cells and its modulation during acute hypoxia

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