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Discovery of Novel 3-Hydroxyquinazoline-2,4(1 H ,3 H )-Dione Derivatives: A Series of Metal Ion Chelators with Potent Anti-HCV Activities

International journal of molecular sciences, 2022-05, Vol.23 (11), p.5930

2022

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Development of Anthraquinone Analogues as Phosphoglycerate Mutase 1 Inhibitors

Molecules (Basel, Switzerland), 2019-02, Vol.24 (5), p.845

2019

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Synthesis and biological evaluation of anthraquinone derivatives as allosteric phosphoglycerate mutase 1 inhibitors for cancer treatment

European journal of medicinal chemistry, 2019-04, Vol.168, p.45-57

2019

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The Design and Synthesis of N -Xanthone Benzenesulfonamides as Novel Phosphoglycerate Mutase 1 (PGAM1) Inhibitors

Molecules (Basel, Switzerland), 2018-06, Vol.23 (6), p.1396

2018

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Efficient preparation of (R)‐2‐(2,5‐difluorophenyl)pyrrolidine via a recycle process of resolution

Chirality (New York, N.Y.), 2021-12, Vol.33 (12), p.931-937

2021

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Identification, synthesis and strategy for minimization of potential impurities in the synthesis of suvorexant

Synthetic communications, 2021-07, Vol.51 (14), p.2225-2236

2021

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Sphingomyelin synthase 2 is a positive regulator of the CSF1R-STAT3 pathway in pancreatic cancer-associated macrophage

Frontiers in pharmacology, 2022-10, Vol.13, p.902016-902016

2022

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Discovery, synthesis and anti-atherosclerotic activities of a novel selective sphingomyelin synthase 2 inhibitor

European journal of medicinal chemistry, 2019-02, Vol.163, p.864-882

2019

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Choline-Derivate-Modified Nanoparticles for Brain-Targeting Gene Delivery

Advanced materials (Weinheim), 2011-10, Vol.23 (39), p.4516-4520

2011

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Rational design of 2-pyrrolinones as inhibitors of HIV-1 integrase

Bioorganic & medicinal chemistry letters, 2011-11, Vol.21 (22), p.6724-6727

2011

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Site-Selective Phosphoglycerate Mutase 1 Acetylation by a Small Molecule

ACS chemical biology, 2020-03, Vol.15 (3), p.632-639

2020

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Pharmacologic inhibition of sphingomyelin synthase (SMS) activity reduces apolipoprotein-B secretion from hepatocytes and attenuates endotoxin-mediated macrophage inflammation

PloS one, 2014-07, Vol.9 (7), p.e102641-e102641

2014

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A novel and practical asymmetric synthesis of dapoxetine hydrochloride

Beilstein journal of organic chemistry, 2015-12, Vol.11 (1), p.2641-2645

2015

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Increasing the Level of IRS-1 and Insulin Pathway Sensitivity by Natural Product Carainterol A

Molecules (Basel, Switzerland), 2016-09, Vol.21 (10), p.1303-1303

2016

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Design and Synthesis of the Diazirine-based Clickable Photo-affinity Probe Targeting Sphingomyelin Synthase 2

Letters in drug design & discovery, 2019-01, Vol.16 (6), p.678-684

2019

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Discovery of Metal Ions Chelator Quercetin Derivatives with Potent Anti-HCV Activities

Molecules (Basel, Switzerland), 2015-04, Vol.20 (4), p.6978-6999

2015

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Identification of small molecule sphingomyelin synthase inhibitors

European journal of medicinal chemistry, 2014-02, Vol.73, p.1-7

2014

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The domain responsible for sphingomyelin synthase (SMS) activity

Biochimica et biophysica acta, 2008-10, Vol.1781 (10), p.610-617

2008

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Novel Dual Inhibitors of Secretory Phospholipase A2 and Sphingomyelin Synthase: Design, Synthesis and Evaluation

Letters in drug design & discovery, 2016-12, Vol.13 (10), p.1025-1032

2016

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Antitumor agents 294. Novel E-ring-modified camptothecin–4β-anilino-4′-O-demethyl-epipodophyllotoxin conjugates as DNA topoisomerase I inhibitors and cytotoxic agents

Bioorganic & medicinal chemistry, 2012-07, Vol.20 (14), p.4489-4494

2012

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Design, Synthesis, and Biological Evaluation of Novel Dual Inhibitors of Secretory Phospholipase A2 and Sphingomyelin Synthase

Chinese journal of chemistry, 2013-09, Vol.31 (9), p.1164-1170

2013

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An efficient one-pot procedure for the synthesis of 1,5-benzothiazepinones catalyzed by tetrabutylammonium fluoride (TBAF)

Tetrahedron letters, 2016-08, Vol.57 (33), p.3743-3745

2016

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Assignment of NMR data and Conformational analysis of larotrectinib and its precursors

Tetrahedron, 2021-04, Vol.85, p.132064, Article 132064

2021

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Discovery of Novel Benzothiazepinones as Irreversible Covalent Glycogen Synthase Kinase 3β Inhibitors for the Treatment of Acute Promyelocytic Leukemia

Journal of medicinal chemistry, 2021-06, Vol.64 (11), p.7341-7358

2021

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Xanthone derivatives as phosphoglycerate mutase 1 inhibitors: Design, synthesis, and biological evaluation

Bioorganic & medicinal chemistry, 2018-05, Vol.26 (8), p.1961-1970

2018

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Discovery of Novel 3-Hydroxyquinazoline-2,4(1 H ,3 H )-Dione Derivatives: A Series of Metal Ion Chelators with Potent Anti-HCV Activities

Development of Anthraquinone Analogues as Phosphoglycerate Mutase 1 Inhibitors

Synthesis and biological evaluation of anthraquinone derivatives as allosteric phosphoglycerate mutase 1 inhibitors for cancer treatment

The Design and Synthesis of N -Xanthone Benzenesulfonamides as Novel Phosphoglycerate Mutase 1 (PGAM1) Inhibitors

Efficient preparation of (R)‐2‐(2,5‐difluorophenyl)pyrrolidine via a recycle process of resolution

Identification, synthesis and strategy for minimization of potential impurities in the synthesis of suvorexant

Sphingomyelin synthase 2 is a positive regulator of the CSF1R-STAT3 pathway in pancreatic cancer-associated macrophage

Discovery, synthesis and anti-atherosclerotic activities of a novel selective sphingomyelin synthase 2 inhibitor

Choline-Derivate-Modified Nanoparticles for Brain-Targeting Gene Delivery

Rational design of 2-pyrrolinones as inhibitors of HIV-1 integrase

Site-Selective Phosphoglycerate Mutase 1 Acetylation by a Small Molecule

Pharmacologic inhibition of sphingomyelin synthase (SMS) activity reduces apolipoprotein-B secretion from hepatocytes and attenuates endotoxin-mediated macrophage inflammation

A novel and practical asymmetric synthesis of dapoxetine hydrochloride

Increasing the Level of IRS-1 and Insulin Pathway Sensitivity by Natural Product Carainterol A

Design and Synthesis of the Diazirine-based Clickable Photo-affinity Probe Targeting Sphingomyelin Synthase 2

Discovery of Metal Ions Chelator Quercetin Derivatives with Potent Anti-HCV Activities

Identification of small molecule sphingomyelin synthase inhibitors

The domain responsible for sphingomyelin synthase (SMS) activity

Novel Dual Inhibitors of Secretory Phospholipase A2 and Sphingomyelin Synthase: Design, Synthesis and Evaluation

Antitumor agents 294. Novel E-ring-modified camptothecin–4β-anilino-4′-O-demethyl-epipodophyllotoxin conjugates as DNA topoisomerase I inhibitors and cytotoxic agents

Design, Synthesis, and Biological Evaluation of Novel Dual Inhibitors of Secretory Phospholipase A2 and Sphingomyelin Synthase

An efficient one-pot procedure for the synthesis of 1,5-benzothiazepinones catalyzed by tetrabutylammonium fluoride (TBAF)

Assignment of NMR data and Conformational analysis of larotrectinib and its precursors

Discovery of Novel Benzothiazepinones as Irreversible Covalent Glycogen Synthase Kinase 3β Inhibitors for the Treatment of Acute Promyelocytic Leukemia

Xanthone derivatives as phosphoglycerate mutase 1 inhibitors: Design, synthesis, and biological evaluation

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