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A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer

Cell metabolism, 2019-12, Vol.30 (6), p.1107-1119.e8

2019

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Sphingomyelin synthase 2 facilitates M2-like macrophage polarization and tumor progression in a mouse model of triple-negative breast cancer

Acta pharmacologica Sinica, 2021-01, Vol.42 (1), p.149-159

2021

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An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma

Proceedings of the National Academy of Sciences - PNAS, 2019-11, Vol.116 (46), p.23264-23273

2019

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Highly Stereoselective and Scalable Synthesis of Eldecalcitol

Organic preparations and procedures international, 2024-01, Vol.56 (1), p.59-71

2024

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Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors

Bioorganic & medicinal chemistry, 2015-09, Vol.23 (18), p.6173-6184

2015

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Discovery and anti-inflammatory evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β)

Bioorganic & medicinal chemistry, 2018-11, Vol.26 (20), p.5479-5493

2018

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The discovery of novel benzothiazinones as highly selective non-ATP competitive glycogen synthase kinase 3β inhibitors for the treatment of ovarian cancer

European journal of medicinal chemistry, 2017-07, Vol.135, p.370-381

2017

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Discovery of styrylaniline derivatives as novel alpha-synuclein aggregates ligands

European journal of medicinal chemistry, 2021-12, Vol.226, p.113887-113887, Article 113887

2021

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Discovery of the selective sphingomyelin synthase 2 inhibitors with the novel structure of oxazolopyridine

Bioorganic & medicinal chemistry letters, 2017-08, Vol.27 (15), p.3511-3515

2017

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Design, synthesis and identification of N, N-dibenzylcinnamamide (DBC) derivatives as novel ligands for α-synuclein fibrils by SPR evaluation system

Bioorganic & medicinal chemistry, 2020-04, Vol.28 (7), p.115358-115358, Article 115358

2020

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Design, synthesis and biological evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β)

European journal of medicinal chemistry, 2013-03, Vol.61, p.95-103

2013

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Tetrazole and triazole as bioisosteres of carboxylic acid: Discovery of diketo tetrazoles and diketo triazoles as anti-HCV agents

Bioorganic & medicinal chemistry letters, 2013-08, Vol.23 (16), p.4528-4531

2013

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Discovery of flavonoid derivatives as anti-HCV agents via pharmacophore search combining molecular docking strategy

European journal of medicinal chemistry, 2012-06, Vol.52, p.33-43

2012

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(E)-3-(8-Benz-yloxy-2,3-dihydro-1,4-benzodioxin-6-yl)-1-[2-hy-droxy-4,6-bis-(meth-oxy-meth-oxy)phen-yl]prop-2-en-1-one

Acta crystallographica. Section E, Structure reports online, 2011-04, Vol.67 (Pt 4), p.o912-o913

2011

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Identification of novel scaffold of benzothiazepinones as non-ATP competitive glycogen synthase kinase-3β inhibitors through virtual screening

Bioorganic & medicinal chemistry letters, 2012-12, Vol.22 (23), p.7232-7236

2012

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Quantitative Trait Loci for Grain Chalkiness and Endosperm Transparency Detected in Three Recombinant Inbred Line Populations of Indica Rice

Journal of Integrative Agriculture, 2013, Vol.12 (1), p.1-11

2013

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Structure-based 3D-QSAR studies on thiazoles as 5-HT3 receptor antagonists

Journal of molecular modeling, 2007-01, Vol.13 (1), p.121-131

2007

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Structure-based 3D-QSAR studies on heteroarylpiperazine derivatives as 5-HT3 receptor antagonists

European journal of medicinal chemistry, 2007-07, Vol.42 (7), p.977-984

2007

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Selective debenzylation of benzyl esters by silica-supported sodium hydrogen sulphate

Chinese chemical letters, 2009-10, Vol.20 (10), p.1157-1160

2009

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2-(Furan-2-yl)-5-(2-nitrobenzyl)-2,3-dihydro-1,5-benzothiazepin-4(5 H )-one

Acta crystallographica. Section E, Structure reports online, 2011-01, Vol.67 (1), p.o168-o168

2011

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A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer

Cell metabolism, 2021-01, Vol.33 (1), p.223-223

2021

Volltextzugriff (PDF)

Identification of novel scaffold of benzothiazepinones as non-ATP competitive glycogen synthase kinase-3[beta] inhibitors through virtual screening

Bioorganic & medicinal chemistry letters, 2012-12, Vol.22 (23), p.7232-7236

2012

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Intramolecular Diels-Alder reaction of pyrazines with an alkenyl side chain

Tetrahedron letters, 1996-11, Vol.37 (45), p.8205-8208

1996

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ChemInform Abstract: Design, Synthesis and Biological Evaluation of Benzothiazepinones (BTZs) as Novel Non-ATP Competitive Inhibitors of Glycogen Synthase Kinase-3β (GSK-3β)

ChemInform, 2013-07, Vol.44 (27), p.no-no

2013

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Reduction of OsFLW7 expression enhanced leaf area and grain production in rice

Science bulletin, 2017-12, Vol.62 (24), p.1631-1633

2017

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A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer

Sphingomyelin synthase 2 facilitates M2-like macrophage polarization and tumor progression in a mouse model of triple-negative breast cancer

An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma

Highly Stereoselective and Scalable Synthesis of Eldecalcitol

Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors

Discovery and anti-inflammatory evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β)

The discovery of novel benzothiazinones as highly selective non-ATP competitive glycogen synthase kinase 3β inhibitors for the treatment of ovarian cancer

Discovery of styrylaniline derivatives as novel alpha-synuclein aggregates ligands

Discovery of the selective sphingomyelin synthase 2 inhibitors with the novel structure of oxazolopyridine

Design, synthesis and identification of N, N-dibenzylcinnamamide (DBC) derivatives as novel ligands for α-synuclein fibrils by SPR evaluation system

Design, synthesis and biological evaluation of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β)

Tetrazole and triazole as bioisosteres of carboxylic acid: Discovery of diketo tetrazoles and diketo triazoles as anti-HCV agents

Discovery of flavonoid derivatives as anti-HCV agents via pharmacophore search combining molecular docking strategy

(E)-3-(8-Benz-yloxy-2,3-dihydro-1,4-benzodioxin-6-yl)-1-[2-hy-droxy-4,6-bis-(meth-oxy-meth-oxy)phen-yl]prop-2-en-1-one

Identification of novel scaffold of benzothiazepinones as non-ATP competitive glycogen synthase kinase-3β inhibitors through virtual screening

Quantitative Trait Loci for Grain Chalkiness and Endosperm Transparency Detected in Three Recombinant Inbred Line Populations of Indica Rice

Structure-based 3D-QSAR studies on thiazoles as 5-HT3 receptor antagonists

Structure-based 3D-QSAR studies on heteroarylpiperazine derivatives as 5-HT3 receptor antagonists

Selective debenzylation of benzyl esters by silica-supported sodium hydrogen sulphate

2-(Furan-2-yl)-5-(2-nitrobenzyl)-2,3-dihydro-1,5-benzothiazepin-4(5 H )-one

A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer

Identification of novel scaffold of benzothiazepinones as non-ATP competitive glycogen synthase kinase-3[beta] inhibitors through virtual screening

Intramolecular Diels-Alder reaction of pyrazines with an alkenyl side chain

ChemInform Abstract: Design, Synthesis and Biological Evaluation of Benzothiazepinones (BTZs) as Novel Non-ATP Competitive Inhibitors of Glycogen Synthase Kinase-3β (GSK-3β)

Reduction of OsFLW7 expression enhanced leaf area and grain production in rice

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