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The Effect of Excipients on the Permeability of BCS Class III Compounds and Implications for Biowaivers

Pharmaceutical research, 2016-01, Vol.33 (1), p.167-176

2016

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Overview of Determination of Biopharmaceutical Properties for Development Candidate Selection

Current protocols, 2023-11, Vol.3 (11), p.e926-n/a

Yazdanian, Mehran

2023

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Discovery and Characterization of 6-{4-[3-(R)-2-Methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, Irdabisant): A Potent, Selective Histamine H3 Receptor Inverse Agonist

Journal of medicinal chemistry, 2011-07, Vol.54 (13), p.4781-4792

2011

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Correlating partitioning and caco-2 cell permeability of structurally diverse small molecular weight compounds

Pharmaceutical research, 1998-09, Vol.15 (9), p.1490-1494

1998

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New directions in pharmaceutical amorphous materials and amorphous solid dispersions, a tribute to Professor George Zografi – Proceedings of the June 2016 Land O’Lakes Conference

AAPS open, 2017-08, Vol.3 (1), p.1-14, Article 7

2017

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Characterization of the Calu-3 cell line as a tool to screen pulmonary drug delivery

International journal of pharmaceutics, 2000-11, Vol.208 (1), p.1-11

2000

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Microparticulate uptake mechanisms of in-vitro cell culture models of the respiratory epithelium

Journal of pharmacy and pharmacology, 2001-01, Vol.53 (1), p.57-66

2001

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Evaluation of an accelerated Caco‐2 cell permeability model

Journal of pharmaceutical sciences, 2000-03, Vol.89 (3), p.336-345

2000

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P-glycoprotein efflux pump expression and activity in Calu-3 cells

Journal of pharmaceutical sciences, 2001-05, Vol.90 (5), p.647-658

2001

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Modulation of P-glycoprotein activity in Calu-3 cells using steroids and β-ligands

International journal of pharmaceutics, 2001-10, Vol.228 (1), p.171-179

2001

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Multidrug resistance-associated protein-1 functional activity in Calu-3 cells

The Journal of pharmacology and experimental therapeutics, 2001-09, Vol.298 (3), p.1199

2001

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Evolution of Choice of Solubility and Dissolution Media After Two Decades of Biopharmaceutical Classification System

The AAPS journal, 2017-07, Vol.19 (4), p.989-1001

2017

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The "high solubility" definition of the current FDA Guidance on Biopharmaceutical Classification System may be too strict for acidic drugs

Pharmaceutical research, 2004-02, Vol.21 (2), p.293-299

2004

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Overview of Determination of Biopharmaceutical Properties for Development Candidate Selection

Current Protocols in Pharmacology, 2013-03, Vol.60 (1), p.9.17.1-9.17.8

Yazdanian, Mehran

2013

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Commentary: Why Pharmaceutical Scientists in Early Drug Discovery Are Critical for Influencing the Design and Selection of Optimal Drug Candidates

AAPS PharmSciTech, 2018, Vol.19 (1), p.1-10

2018

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Lipophilicity in Drug Development: Too Much or Not Enough?

The AAPS journal, 2016-09, Vol.18 (5), p.1095-1100

2016

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Ionic interactions of fatty acid monolayers at the air/water interface

Langmuir, 1990-06, Vol.6 (6), p.1093-1098

1990

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A Comprehensive Study Demonstrating that P-glycoprotein Function is Directly Affected by Changes in pH: Implications for Intestinal pH and Effects on Drug Absorption

Journal of pharmaceutical sciences, 2011-10, Vol.100 (10), p.4258-4268

2011

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The effect of freezing on cattle skin permeability

International journal of pharmaceutics, 1994-02, Vol.103 (1), p.93-96

Yazdanian, Mehran

1994

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A structure–Permeability study of small drug-like molecules

Bioorganic & medicinal chemistry letters, 2003-02, Vol.13 (4), p.719-722

2003

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CEP-32496: a novel orally active BRAF(V600E) inhibitor with selective cellular and in vivo antitumor activity

Molecular cancer therapeutics, 2012-04, Vol.11 (4), p.930-941

2012

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Mechanisms of transport and structure-permeability relationship of sulfasalazine and its analogs in Caco-2 cell monolayers

Pharmaceutical research, 2000-10, Vol.17 (10), p.1168-1174

2000

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In Vitro Blood–Brain Barrier Permeability of Nevirapine Compared to Other HIV Antiretroviral Agents

Journal of pharmaceutical sciences, 1998-03, Vol.87 (3), p.306-310

1998

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Tetrazole compounds: The effect of structure and pH on Caco-2 cell permeability

Journal of pharmaceutical sciences, 2006-04, Vol.95 (4), p.717-725

2006

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2,7-Disubstituted-Pyrrolotriazine Kinase Inhibitors with an Unusually High Degree of Reactive Metabolite Formation

Chemical research in toxicology, 2011-11, Vol.24 (11), p.1994-2003

2011

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The Effect of Excipients on the Permeability of BCS Class III Compounds and Implications for Biowaivers

Overview of Determination of Biopharmaceutical Properties for Development Candidate Selection

Discovery and Characterization of 6-{4-[3-(R)-2-Methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, Irdabisant): A Potent, Selective Histamine H3 Receptor Inverse Agonist

Correlating partitioning and caco-2 cell permeability of structurally diverse small molecular weight compounds

New directions in pharmaceutical amorphous materials and amorphous solid dispersions, a tribute to Professor George Zografi – Proceedings of the June 2016 Land O’Lakes Conference

Characterization of the Calu-3 cell line as a tool to screen pulmonary drug delivery

Microparticulate uptake mechanisms of in-vitro cell culture models of the respiratory epithelium

Evaluation of an accelerated Caco‐2 cell permeability model

P-glycoprotein efflux pump expression and activity in Calu-3 cells

Modulation of P-glycoprotein activity in Calu-3 cells using steroids and β-ligands

Multidrug resistance-associated protein-1 functional activity in Calu-3 cells

Evolution of Choice of Solubility and Dissolution Media After Two Decades of Biopharmaceutical Classification System

The "high solubility" definition of the current FDA Guidance on Biopharmaceutical Classification System may be too strict for acidic drugs

Overview of Determination of Biopharmaceutical Properties for Development Candidate Selection

Commentary: Why Pharmaceutical Scientists in Early Drug Discovery Are Critical for Influencing the Design and Selection of Optimal Drug Candidates

Lipophilicity in Drug Development: Too Much or Not Enough?

Ionic interactions of fatty acid monolayers at the air/water interface

A Comprehensive Study Demonstrating that P-glycoprotein Function is Directly Affected by Changes in pH: Implications for Intestinal pH and Effects on Drug Absorption

The effect of freezing on cattle skin permeability

A structure–Permeability study of small drug-like molecules

CEP-32496: a novel orally active BRAF(V600E) inhibitor with selective cellular and in vivo antitumor activity

Mechanisms of transport and structure-permeability relationship of sulfasalazine and its analogs in Caco-2 cell monolayers

In Vitro Blood–Brain Barrier Permeability of Nevirapine Compared to Other HIV Antiretroviral Agents

Tetrazole compounds: The effect of structure and pH on Caco-2 cell permeability

2,7-Disubstituted-Pyrrolotriazine Kinase Inhibitors with an Unusually High Degree of Reactive Metabolite Formation

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