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Vitamin D levels do not cause vitamin-drug interactions with dexamethasone or dasatinib in mice

PloS one, 2021-10, Vol.16 (10)

2021

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Pheophorbide A: Fluorescent Bcrp Substrate to Measure Oral Drug-Drug Interactions in Real-Time In Vivo

Drug metabolism and disposition, 2018-11, Vol.46 (11), p.1725-1733

2018

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Vitamin D levels do not cause vitamin-drug interactions with dexamethasone or dasatinib in mice

PloS one, 2021-10, Vol.16 (10), p.e0258579

2021

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Drug transporters on arachnoid barrier cells contribute to the blood-cerebrospinal fluid barrier

Drug metabolism and disposition, 2013-04, Vol.41 (4), p.923

2013

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Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters

PloS one, 2021-07, Vol.16 (7), p.e0253852-e0253852

2021

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Role of Vitamins A and D in BCR-ABL Arf -/- Acute Lymphoblastic Leukemia

Scientific reports, 2020-02, Vol.10 (1), p.2359-2359, Article 2359

2020

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Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

Nature genetics, 2001-04, Vol.27 (4), p.383-391

2001

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Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression

The Journal of pharmacology and experimental therapeutics, 2003-12, Vol.307 (3), p.906

2003

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A comprehensive in vitro and in silico analysis of antibiotics that activate pregnane X receptor and induce CYP3A4 in liver and intestine

Drug metabolism and disposition, 2008-08, Vol.36 (8), p.1689

2008

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Interactions between Hepatic Mrp4 and Sult2a as Revealed by the Constitutive Androstane Receptor and Mrp4 Knockout Mice

The Journal of biological chemistry, 2004-05, Vol.279 (21), p.22250-22257

2004

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Disrupted Bile Acid Homeostasis Reveals an Unexpected Interaction among Nuclear Hormone Receptors, Transporters, and Cytochrome P450

The Journal of biological chemistry, 2001-10, Vol.276 (42), p.39411-39418

2001

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Genetic variation in aldo-keto reductase 1D1 (AKR1D1) affects the expression and activity of multiple cytochrome P450s

Drug metabolism and disposition, 2013-08, Vol.41 (8), p.1538

2013

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Evolution of the Pregnane X Receptor: Adaptation to Cross-Species Differences in Biliary Bile Salts

Molecular endocrinology (Baltimore, Md.), 2005-07, Vol.19 (7), p.1720-1739

2005

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Interaction of cytochrome P450 3A inhibitors with P-glycoprotein

The Journal of pharmacology and experimental therapeutics, 2002-10, Vol.303 (1), p.323

2002

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Expression of constitutive androstane receptor splice variants in human tissues and their functional consequences

The Journal of pharmacology and experimental therapeutics, 2004-11, Vol.311 (2), p.811

2004

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Application of Three-Dimensional Quantitative Structure-Activity Relationships of P-Glycoprotein Inhibitors and Substrates

Molecular pharmacology, 2002-05, Vol.61 (5), p.974-981

2002

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Three-Dimensional Quantitative Structure-Activity Relationships of Inhibitors of P-Glycoprotein

Molecular pharmacology, 2002-05, Vol.61 (5), p.964-973

2002

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The major human pregnane X receptor (PXR) splice variant, PXR.2, exhibits significantly diminished ligand-activated transcriptional regulation

Drug metabolism and disposition, 2009-06, Vol.37 (6), p.1295

2009

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Structural determinants of P-glycoprotein-mediated transport of glucocorticoids

Pharmaceutical research, 2003-11, Vol.20 (11), p.1794-1803

2003

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Altered Expression of Hepatic Cytochromes P-450 in Mice Deficient in One or More mdr1 Genes

Molecular pharmacology, 2000-01, Vol.57 (1), p.188-197

2000

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Development of A Real-Time in Vivo Transcription Assay: Application Reveals Pregnane X Receptor-Mediated Induction of CYP3A4 by Cancer Chemotherapeutic Agents

Molecular pharmacology, 2002-09, Vol.62 (3), p.439-445

2002

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The glucocorticoid receptor is essential for induction of cytochrome P-4502B by steroids but not for drug or steroid induction of CYP3A or P-450 reductase in mouse liver

Drug metabolism and disposition, 2000-03, Vol.28 (3), p.268

2000

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Role of the nuclear receptor pregnane X receptor in acetaminophen hepatotoxicity

Drug metabolism and disposition, 2005-12, Vol.33 (12), p.1827

2005

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Bromocriptine Reverses P‐Glycoprotein‐mediated Multidrug Resistance in Tumor Cells

Cancer science, 2002-02, Vol.93 (2), p.209-215

2002

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CRISPR/Cas9 Genetic Modification of CYP3A5 3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism

Drug metabolism and disposition, 2017-08, Vol.45 (8), p.957-965

2017

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Vitamin D levels do not cause vitamin-drug interactions with dexamethasone or dasatinib in mice

Pheophorbide A: Fluorescent Bcrp Substrate to Measure Oral Drug-Drug Interactions in Real-Time In Vivo

Vitamin D levels do not cause vitamin-drug interactions with dexamethasone or dasatinib in mice

Drug transporters on arachnoid barrier cells contribute to the blood-cerebrospinal fluid barrier

Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters

Role of Vitamins A and D in BCR-ABL Arf -/- Acute Lymphoblastic Leukemia

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression

A comprehensive in vitro and in silico analysis of antibiotics that activate pregnane X receptor and induce CYP3A4 in liver and intestine

Interactions between Hepatic Mrp4 and Sult2a as Revealed by the Constitutive Androstane Receptor and Mrp4 Knockout Mice

Disrupted Bile Acid Homeostasis Reveals an Unexpected Interaction among Nuclear Hormone Receptors, Transporters, and Cytochrome P450

Genetic variation in aldo-keto reductase 1D1 (AKR1D1) affects the expression and activity of multiple cytochrome P450s

Evolution of the Pregnane X Receptor: Adaptation to Cross-Species Differences in Biliary Bile Salts

Interaction of cytochrome P450 3A inhibitors with P-glycoprotein

Expression of constitutive androstane receptor splice variants in human tissues and their functional consequences

Application of Three-Dimensional Quantitative Structure-Activity Relationships of P-Glycoprotein Inhibitors and Substrates

Three-Dimensional Quantitative Structure-Activity Relationships of Inhibitors of P-Glycoprotein

The major human pregnane X receptor (PXR) splice variant, PXR.2, exhibits significantly diminished ligand-activated transcriptional regulation

Structural determinants of P-glycoprotein-mediated transport of glucocorticoids

Altered Expression of Hepatic Cytochromes P-450 in Mice Deficient in One or More mdr1 Genes

Development of A Real-Time in Vivo Transcription Assay: Application Reveals Pregnane X Receptor-Mediated Induction of CYP3A4 by Cancer Chemotherapeutic Agents

The glucocorticoid receptor is essential for induction of cytochrome P-4502B by steroids but not for drug or steroid induction of CYP3A or P-450 reductase in mouse liver

Role of the nuclear receptor pregnane X receptor in acetaminophen hepatotoxicity

Bromocriptine Reverses P‐Glycoprotein‐mediated Multidrug Resistance in Tumor Cells

CRISPR/Cas9 Genetic Modification of CYP3A5 3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism

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