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Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain

Nature chemical biology, 2021-07, Vol.17 (7), p.784

2021

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Design, synthesis, and biological evaluation of 1, 3-disubstituted-pyrazole derivatives as new class I and IIb histone deacetylase inhibitors

European journal of medicinal chemistry, 2014-10, Vol.86, p.639-652

2014

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Practical access to four stereoisomers of naftidrofuryl and their binding affinity towards 5-hydroxytryptamine 2A receptor

Bioorganic & medicinal chemistry letters, 2012-05, Vol.22 (10), p.3441-3444

2012

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High effective medical image segmentation with model adjustable method

2013 IEEE International Symposium on Circuits and Systems (ISCAS), 2013, p.1512-1515

2013

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Discovery of Novel Class I Histone Deacetylase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities

Journal of medicinal chemistry, 2015-10, Vol.58 (19), p.7672-7680

2015

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The decimator with multiplier-free realizations for high precision ADC applications

2013 IEEE 10th International Conference on ASIC, 2013, p.1-4

2013

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Quantized Winograd Acceleration for CONV1D Equipped ASR Models on Mobile Devices

ICASSP 2022 - 2022 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), 2022, p.4803-4807

2022

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Structure-Based Design of a Selective Class I Histone Deacetylase (HDAC) Near-Infrared (NIR) Probe for Epigenetic Regulation Detection in Triple-Negative Breast Cancer (TNBC)

Journal of medicinal chemistry, 2021-04, Vol.64 (7), p.4020-4033

2021

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Dual nicotinamide phosphoribosyltransferase and epidermal growth factor receptor inhibitors for the treatment of cancer

European journal of medicinal chemistry, 2021-02, Vol.211, p.113022, Article 113022

2021

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Total synthesis of securinega alkaloids (-)-norsecurinine, (-)-niruroidine and (-)-flueggine A

Chemical communications (Cambridge, England), 2014-08, Vol.50 (66), p.9284-9287

2014

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Discovery of class I histone deacetylase inhibitors based on romidpesin with promising selectivity for cancer cells

Future medicinal chemistry, 2020-02, Vol.12 (4), p.311-323

2020

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Effective Pipeline for Compressing Deep Object Detectors

ICASSP 2020 - 2020 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), 2020, p.4472-4476

2020

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Design, synthesis, and biological evaluation of largazole derivatives: alteration of the zinc-binding domain

Tetrahedron, 2014-10, Vol.70 (42), p.7763-7769

2014

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Unprecedented reactions: from epichlorohydrin to epoxyglycidyl substituted divinyl ether and its conversion into epoxyglycidyl propargyl ether

Scientific reports, 2015-09, Vol.5 (1), p.14231-14231, Article 14231

2015

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Design, synthesis, and biological evaluation of novel histone deacetylase 1 inhibitors through click chemistry

Bioorganic & medicinal chemistry letters, 2013-06, Vol.23 (11), p.3295-3299

2013

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Depletion of γ-catenin by Histone Deacetylase Inhibition Confers Elimination of CML Stem Cells in Combination with Imatinib

Theranostics, 2016-01, Vol.6 (11), p.1947-1962

2016

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Total synthesis of securinega alkaloids (−)-norsecurinine, (−)-niruroidine and (−)-flueggine AElectronic supplementary information (ESI) available: Experimental procedures and characterization data for all new compounds described herein, including CIF files for compounds 15 and 20. CCDC 971441 and 971455. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4cc02575j

2014-07

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Abstract 6286: Targeting Polycomb Repressive Complex 1 with small-molecule inhibitors as a potential therapeutic approach to combat leukemia

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.6286-6286

2023

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Biological Evaluation of New Largazole Analogues: Alteration of Macrocyclic Scaffold with Click Chemistry

ACS medicinal chemistry letters, 2013-01, Vol.4 (1), p.132-136

2013

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PQJS380: A novel lead compound to induce apoptosis in acute lymphoblastic leukemia cells

Cancer biology & therapy, 2014-01, Vol.15 (1), p.119-127

2014

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An information integration system of signal intersection with multi-mode traffic data collection and analysis

2012 IEEE International Symposium on Industrial Electronics, 2012, p.914-919

2012

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A low power IC for efficient de-interlacing based on refined motion adaptive method

2012 IEEE International Symposium on Industrial Electronics, 2012, p.1094-1099

2012

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Efficient Implementation of Convolutional Neural Networks with End to End Integer-Only Dataflow

2019 IEEE International Conference on Multimedia and Expo (ICME), 2019, p.1780-1785

2019

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ChemInform Abstract: 8-Hydroxyquinolin-N-oxide-Promoted Copper-Catalyzed C-S Cross-Coupling of Thiols with Aryl Iodides

ChemInform, 2013-03, Vol.44 (13), p.no-no

2013

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De novo design and directed folding of disulfide-bridged peptide heterodimers

Nature communications, 2022-03, Vol.13 (1), p.1539-1539, Article 1539

2022

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Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain

Design, synthesis, and biological evaluation of 1, 3-disubstituted-pyrazole derivatives as new class I and IIb histone deacetylase inhibitors

Practical access to four stereoisomers of naftidrofuryl and their binding affinity towards 5-hydroxytryptamine 2A receptor

High effective medical image segmentation with model adjustable method

Discovery of Novel Class I Histone Deacetylase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities

The decimator with multiplier-free realizations for high precision ADC applications

Quantized Winograd Acceleration for CONV1D Equipped ASR Models on Mobile Devices

Structure-Based Design of a Selective Class I Histone Deacetylase (HDAC) Near-Infrared (NIR) Probe for Epigenetic Regulation Detection in Triple-Negative Breast Cancer (TNBC)

Dual nicotinamide phosphoribosyltransferase and epidermal growth factor receptor inhibitors for the treatment of cancer

Total synthesis of securinega alkaloids (-)-norsecurinine, (-)-niruroidine and (-)-flueggine A

Discovery of class I histone deacetylase inhibitors based on romidpesin with promising selectivity for cancer cells

Effective Pipeline for Compressing Deep Object Detectors

Design, synthesis, and biological evaluation of largazole derivatives: alteration of the zinc-binding domain

Unprecedented reactions: from epichlorohydrin to epoxyglycidyl substituted divinyl ether and its conversion into epoxyglycidyl propargyl ether

Design, synthesis, and biological evaluation of novel histone deacetylase 1 inhibitors through click chemistry

Depletion of γ-catenin by Histone Deacetylase Inhibition Confers Elimination of CML Stem Cells in Combination with Imatinib

Abstract 6286: Targeting Polycomb Repressive Complex 1 with small-molecule inhibitors as a potential therapeutic approach to combat leukemia

Biological Evaluation of New Largazole Analogues: Alteration of Macrocyclic Scaffold with Click Chemistry

PQJS380: A novel lead compound to induce apoptosis in acute lymphoblastic leukemia cells

An information integration system of signal intersection with multi-mode traffic data collection and analysis

A low power IC for efficient de-interlacing based on refined motion adaptive method

Efficient Implementation of Convolutional Neural Networks with End to End Integer-Only Dataflow

ChemInform Abstract: 8-Hydroxyquinolin-N-oxide-Promoted Copper-Catalyzed C-S Cross-Coupling of Thiols with Aryl Iodides

De novo design and directed folding of disulfide-bridged peptide heterodimers

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