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Humanized mice in studying efficacy and mechanisms of PD‐1‐targeted cancer immunotherapy

The FASEB journal, 2018-03, Vol.32 (3), p.1537-1549

2018

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Innovations, challenges, and minimal information for standardization of humanized mice

EMBO molecular medicine, 2020-07, Vol.12 (7), p.e8662-n/a

2020

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Plasticity of Button-Like Junctions in the Endothelium of Airway Lymphatics in Development and Inflammation

The American journal of pathology, 2012-06, Vol.180 (6), p.2561-2575

2012

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VEGF and c-Met Blockade Amplify Angiogenesis Inhibition in Pancreatic Islet Cancer

Cancer research (Chicago, Ill.), 2011-07, Vol.71 (14), p.4758-4768

2011

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Simultaneous evaluation of treatment efficacy and toxicity for bispecific T‐cell engager therapeutics in a humanized mouse model

The FASEB journal, 2023-06, Vol.37 (6), p.e22995-n/a

2023

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Pulmonary Lymphangiectasia Resulting From Vascular Endothelial Growth Factor-C Overexpression During a Critical Period

Circulation research, 2014-02, Vol.114 (5), p.806-822

2014

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1232 PBMC humanized mouse model with clinical relevance in assessing the safety profile of 4–1BB agonist, urelumab, in 5 donors

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1359-A1359

2023

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Steroid-Resistant Lymphatic Remodeling in Chronically Inflamed Mouse Airways

The American journal of pathology, 2010-03, Vol.176 (3), p.1525-1541

2010

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Rapamycin reversal of VEGF-C-driven lymphatic anomalies in the respiratory tract

JCI insight, 2017-08, Vol.2 (16)

2017

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Multiple modular promoter elements drive graded brinker expression in response to the Dpp morphogen gradient

Development (Cambridge), 2008-06, Vol.135 (12), p.2183-2192

2008

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Rapid remodeling of airway vascular architecture at birth

Developmental dynamics, 2010-09, Vol.239 (9), p.2354-2366

2010

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TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice

The Journal of clinical investigation, 2009-10, Vol.119 (10), p.2954-2964

2009

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Schnurri transcription factors from Drosophila and vertebrates can mediate Bmp signaling through a phylogenetically conserved mechanism

Development (Cambridge), 2006-10, Vol.133 (20), p.4025-4034

2006

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Two Pax genes, eye gone and eyeless, act cooperatively in promoting Drosophila eye development

Development (Cambridge), 2003-07, Vol.130 (13), p.2939-2951

2003

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Enhanced development of functional human NK cells in NOD-scid-IL2rg null mice expressing human IL15

The FASEB journal, 2022-09, Vol.36 (9), p.e22476

2022

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Enhanced development of functional human NK cells in NOD‐scid‐IL2rgnull mice expressing human IL15

The FASEB journal, 2022-09, Vol.36 (9), p.e22476-n/a

2022

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Plasticity of airway lymphatics in development and disease

Advances in anatomy, embryology and cell biology, 2014, Vol.214, p.41

2014

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Neutrophil Dependence of Vascular Remodeling after Mycoplasma Infection of Mouse Airways

The American journal of pathology, 2014-06, Vol.184 (6), p.1877-1889

2014

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α5β1 Integrin Blockade Inhibits Lymphangiogenesis in Airway Inflammation

The American journal of pathology, 2009, Vol.174 (6), p.2378-2387

2009

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A Common Mechanism for Antenna-to-Leg Transformation in Drosophila: Suppression of homothorax Transcription by Four HOM-C Genes

Developmental biology, 1999-07, Vol.211 (2), p.268-276

1999

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Development of a Novel Solid Tumor-Bearing Humanized Animal Model for Simultaneously Evaluating the Toxicity and Efficacy of Bispecific T Cell Engager

Blood, 2023-11, Vol.142 (Supplement 1), p.6837-6837

2023

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A novel tumor-bearing humanized mouse model for evaluating the efficacy and predictive safety of bispecific T cell engager

The Journal of immunology (1950), 2023-05, Vol.210 (1_Supplement), p.230-230.18

2023

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Abstract 6718: Evaluating toxicity and efficacy of bispecific EGFRXCD3 T cell engager in solid tumor-bearing humanized animal model

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.6718-6718

2024

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Abstract 3320: Humanized NSG-Tg(Hu-IL15) mice support preclinical immune-oncology efficacy for testing of NK cells based immunology

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.3320-3320

2020

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Humanized mice in studying efficacy and mechanisms of PD‐1‐targeted cancer immunotherapy

Innovations, challenges, and minimal information for standardization of humanized mice

Plasticity of Button-Like Junctions in the Endothelium of Airway Lymphatics in Development and Inflammation

VEGF and c-Met Blockade Amplify Angiogenesis Inhibition in Pancreatic Islet Cancer

Simultaneous evaluation of treatment efficacy and toxicity for bispecific T‐cell engager therapeutics in a humanized mouse model

Characterization of the Selective Indoleamine 2,3-Dioxygenase-1 (IDO1) Catalytic Inhibitor EOS200271/PF-06840003 Supports IDO1 as a Critical Resistance Mechanism to PD-(L)1 Blockade Therapy

Pulmonary Lymphangiectasia Resulting From Vascular Endothelial Growth Factor-C Overexpression During a Critical Period

1232 PBMC humanized mouse model with clinical relevance in assessing the safety profile of 4–1BB agonist, urelumab, in 5 donors

Steroid-Resistant Lymphatic Remodeling in Chronically Inflamed Mouse Airways

Rapamycin reversal of VEGF-C-driven lymphatic anomalies in the respiratory tract

Multiple modular promoter elements drive graded brinker expression in response to the Dpp morphogen gradient

Rapid remodeling of airway vascular architecture at birth

TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice

Schnurri transcription factors from Drosophila and vertebrates can mediate Bmp signaling through a phylogenetically conserved mechanism

Two Pax genes, eye gone and eyeless, act cooperatively in promoting Drosophila eye development

Enhanced development of functional human NK cells in NOD-scid-IL2rg null mice expressing human IL15

Enhanced development of functional human NK cells in NOD‐scid‐IL2rgnull mice expressing human IL15

Plasticity of airway lymphatics in development and disease

Neutrophil Dependence of Vascular Remodeling after Mycoplasma Infection of Mouse Airways

α5β1 Integrin Blockade Inhibits Lymphangiogenesis in Airway Inflammation

A Common Mechanism for Antenna-to-Leg Transformation in Drosophila: Suppression of homothorax Transcription by Four HOM-C Genes

Development of a Novel Solid Tumor-Bearing Humanized Animal Model for Simultaneously Evaluating the Toxicity and Efficacy of Bispecific T Cell Engager

A novel tumor-bearing humanized mouse model for evaluating the efficacy and predictive safety of bispecific T cell engager

Abstract 6718: Evaluating toxicity and efficacy of bispecific EGFRXCD3 T cell engager in solid tumor-bearing humanized animal model

Abstract 3320: Humanized NSG-Tg(Hu-IL15) mice support preclinical immune-oncology efficacy for testing of NK cells based immunology

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