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Machine Learning: A New Approach for Dose Individualization

Clinical pharmacology and therapeutics, 2024-04, Vol.115 (4), p.727-744

2024

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Optimal dose of meropenem for the treatment of neonatal sepsis: Dosing guideline variations and clinical practice deviations

British journal of clinical pharmacology, 2022-07, Vol.88 (7), p.3483-3489

2022

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Clinical utility of a model‐based amoxicillin dosage regimen in neonates with early‐onset sepsis

British journal of clinical pharmacology, 2022-11, Vol.88 (11), p.4950-4955

2022

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Clinical utiliy of a model‐based piperacillin dose in neonates with early‐onset sepsis

British journal of clinical pharmacology, 2022-03, Vol.88 (3), p.1179-1188

2022

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Population pharmacokinetics-pharmacodynamics of ceftazidime in neonates and young infants: Dosing optimization for neonatal sepsis

European journal of pharmaceutical sciences, 2021-08, Vol.163, p.105868-105868, Article 105868

2021

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Optimal Sample Size for Use in Neonatal Pharmacokinetic Studies

Therapeutic innovation & regulatory science, 2022-05, Vol.56 (3), p.517-522

2022

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Developmental Population Pharmacokinetics and Dosing Optimization of Cefepime in Neonates and Young Infants

Frontiers in pharmacology, 2020-02, Vol.11, p.14

2020

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Developmental Population Pharmacokinetics-Pharmacodynamics of Meropenem in Chinese Neonates and Young Infants: Dosing Recommendations for Late-Onset Sepsis

Children (Basel), 2022-12, Vol.9 (12), p.1998

2022

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Population Pharmacokinetic Study of Cefathiamidine in Infants With Augmented Renal Clearance

Frontiers in pharmacology, 2021-03, Vol.12, p.630047

2021

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Population pharmacokinetics and dosing optimization of mezlocillin in neonates and young infants

Journal of antimicrobial chemotherapy, 2022-07, Vol.77 (8), p.2238-2244

2022

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Use of Machine Learning for Dosage Individualization of Vancomycin in Neonates

Clinical pharmacokinetics, 2023-08, Vol.62 (8), p.1105-1116

2023

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Population pharmacokinetics and dosing optimization of azlocillin in neonates with early-onset sepsis: a real-world study

Journal of antimicrobial chemotherapy, 2021-02, Vol.76 (3), p.699-709

2021

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A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects

European journal of pharmaceutical sciences, 2023-12, Vol.191, p.106598-106598, Article 106598

2023

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Aciclovir CSF concentration in children with viral encephalitis: is it adequate?

Journal of antimicrobial chemotherapy, 2018-09, Vol.73 (9), p.2582-2583

2018

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18 Use of machine learning for dosage individualization of vancomycin in neonates

BMJ paediatrics open, 2024-08, Vol.8 (Suppl 6), p.A8-A9

2024

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21 A first-in-human phase 1 study of SIM0417, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects

BMJ paediatrics open, 2024-08, Vol.8 (Suppl 6), p.A9-A10

2024

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Model-informed drug development in pediatric, pregnancy and geriatric drug development: States of the art and future

Advanced drug delivery reviews, 2024-08, Vol.211, p.115364, Article 115364

2024

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Predictive Performance of Pharmacokinetic Model-Based Virtual Trials of Vancomycin in Neonates: Mathematics Matches Clinical Observation

Clinical pharmacokinetics, 2022-07, Vol.61 (7), p.1027-1038

2022

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Machine Learning Approach in Dosage Individualization of Isoniazid for Tuberculosis

Clinical pharmacokinetics, 2024-07, Vol.63 (7), p.1055-1063

2024

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Optimal use of β-lactams in neonates: machine learning-based clinical decision support system

EBioMedicine, 2024-07, Vol.105, p.105221, Article 105221

2024

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Optimal use of β-lactams in neonates: machine learning-based clinical decision support systemResearch in context

EBioMedicine, 2024-07, Vol.105, p.105221

2024

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Visualizing the multi-level assembly structures of conjugated molecular systems with chain-length dependent behavior

Nature communications, 2023-06, Vol.14 (1), p.3340-3340, Article 3340

2023

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The comparison researches of cis/trans-butenedioic acids in regulating solid crystalline forms and improving pharmaceutical properties of antifungal drug econazole

Journal of molecular structure, 2022-09, Vol.1263, p.133183, Article 133183

2022

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NNT-AS1 modulates prostate cancer cell proliferation, apoptosis and migration through miR-496/DDIT4 axis

Cancer cell international, 2020-09, Vol.20 (1), p.463-463, Article 463

2020

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Machine Learning: A New Approach for Dose Individualization

Optimal dose of meropenem for the treatment of neonatal sepsis: Dosing guideline variations and clinical practice deviations

Clinical utility of a model‐based amoxicillin dosage regimen in neonates with early‐onset sepsis

Clinical utiliy of a model‐based piperacillin dose in neonates with early‐onset sepsis

Population pharmacokinetics-pharmacodynamics of ceftazidime in neonates and young infants: Dosing optimization for neonatal sepsis

Optimal Sample Size for Use in Neonatal Pharmacokinetic Studies

Developmental Population Pharmacokinetics and Dosing Optimization of Cefepime in Neonates and Young Infants

Developmental Population Pharmacokinetics-Pharmacodynamics of Meropenem in Chinese Neonates and Young Infants: Dosing Recommendations for Late-Onset Sepsis

Population Pharmacokinetic Study of Cefathiamidine in Infants With Augmented Renal Clearance

Population pharmacokinetics and dosing optimization of mezlocillin in neonates and young infants

Use of Machine Learning for Dosage Individualization of Vancomycin in Neonates

Drug Clearance in Neonates: A Combination of Population Pharmacokinetic Modelling and Machine Learning Approaches to Improve Individual Prediction

Population pharmacokinetics and dosing optimization of azlocillin in neonates with early-onset sepsis: a real-world study

A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects

Aciclovir CSF concentration in children with viral encephalitis: is it adequate?

18 Use of machine learning for dosage individualization of vancomycin in neonates

21 A first-in-human phase 1 study of SIM0417, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects

Model-informed drug development in pediatric, pregnancy and geriatric drug development: States of the art and future

Predictive Performance of Pharmacokinetic Model-Based Virtual Trials of Vancomycin in Neonates: Mathematics Matches Clinical Observation

Machine Learning Approach in Dosage Individualization of Isoniazid for Tuberculosis

Optimal use of β-lactams in neonates: machine learning-based clinical decision support system

Optimal use of β-lactams in neonates: machine learning-based clinical decision support systemResearch in context

Visualizing the multi-level assembly structures of conjugated molecular systems with chain-length dependent behavior

The comparison researches of cis/trans-butenedioic acids in regulating solid crystalline forms and improving pharmaceutical properties of antifungal drug econazole

NNT-AS1 modulates prostate cancer cell proliferation, apoptosis and migration through miR-496/DDIT4 axis

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