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Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors for the treatment of non-small cell lung cancer: a patent review (2014-present)

Expert opinion on therapeutic patents, 2021-03, Vol.31 (3), p.223-238

2021

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Synthesis of Halogenated 1,5-Diarylimidazoles and Their Inhibitory Effects on LPS-Induced PGE2 Production in RAW 264.7 Cells

Molecules (Basel, Switzerland), 2021-10, Vol.26 (20), p.6093

2021

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Design, Synthesis, and Biological Evaluation of Novel Thienopyrimidine Derivatives as PI3Kα Inhibitors

Molecules (Basel, Switzerland), 2019-09, Vol.24 (19), p.3422

2019

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Design, Synthesis and Biological Evaluation of Novel Phenylsulfonylurea Derivatives as PI3K/mTOR Dual Inhibitors

Molecules (Basel, Switzerland), 2018-06, Vol.23 (7), p.1553

2018

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Optimisation of novel 4, 8-disubstituted dihydropyrimido[5,4-b][1,4]oxazine derivatives as potent GPR 119 agonists

Journal of enzyme inhibition and medicinal chemistry, 2020-01, Vol.35 (1), p.50-58

2020

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Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus

BMC cancer, 2019-08, Vol.19 (1), p.837-15, Article 837

2019

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Synthesis, Biological Evaluation, and Mode of Action of Pulsatilla Saponin D Derivatives as Promising Anticancer Agents

Frontiers in pharmacology, 2019-10, Vol.10, p.1208-1208

2019

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Discovery of Triazolo-pyridazine/-pyrimidine Derivatives Bearing Aromatic (Heterocycle)-Coupled Azole Units as Class II c‑Met Inhibitors

ACS omega, 2020-07, Vol.5 (27), p.16482-16490

2020

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Discovery of novel quinazoline derivatives bearing semicarbazone moiety as potent EGFR kinase inhibitors

Computational and structural biotechnology journal, 2018-01, Vol.16, p.462-478

2018

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The new opportunities in medicinal chemistry of fourth-generation EGFR inhibitors to overcome C797S mutation

European journal of medicinal chemistry, 2021-01, Vol.210, p.112995-112995, Article 112995

2021

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Synthesis of 1,5-diarylhaloimidazole analogs and their inhibitory activities against PGE2 production from LPS-treated RAW 264.7 cells

Bioorganic & medicinal chemistry, 2012-11, Vol.20 (21), p.6256-6259

2012

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Synthesis and biological evaluation of pyrimidine derivatives with diverse azabicyclic ether/amine as novel GPR119 agonist

Bioorganic & medicinal chemistry letters, 2017-06, Vol.27 (11), p.2515-2519

2017

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Research progress of PROTACs for neurodegenerative diseases therapy

Bioorganic chemistry, 2024-06, Vol.147, p.107386-107386, Article 107386

2024

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GPR119 agonists for the treatment of type 2 diabetes: an updated patent review (2014-present)

Expert opinion on therapeutic patents, 2021-09, Vol.31 (9), p.795-808

2021

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Discovery of thiapyran-pyrimidine derivatives as potential EGFR inhibitors

Bioorganic & medicinal chemistry, 2020-10, Vol.28 (19), p.115669-115669, Article 115669

2020

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Design, synthesis and 3D-QSAR analysis of novel thiopyranopyrimidine derivatives as potential antitumor agents inhibiting A549 and Hela cancer cells

European journal of medicinal chemistry, 2020-01, Vol.185, p.111809, Article 111809

2020

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Discovery of Selective Proteolysis-Targeting Chimera Degraders Targeting PTP1B as Long-Term Hypoglycemic Agents

Journal of medicinal chemistry, 2024-05, Vol.67 (9), p.7569-7584

2024

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Nitric oxide/paclitaxel micelles enhance anti-liver cancer effects and paclitaxel sensitivity by inducing ferroptosis, endoplasmic reticulum stress and pyroptosis

RSC advances, 2023-10, Vol.13 (45), p.31772-31784

2023

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Evaluation of novel paclitaxel-loaded NO-donating polymeric micelles for an improved therapy for gastroenteric tumor

New journal of chemistry, 2021-08, Vol.45 (31), p.13763-13774

2021

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Design and synthesis of novel pyrimido[5,4-d]pyrimidine derivatives as GPR119 agonist for treatment of type 2 diabetes

Bioorganic & medicinal chemistry, 2018-08, Vol.26 (14), p.4080-4087

2018

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Novel 5-nitropyrimidine derivatives bearing endo-azabicyclic alcohols/amines as potent GPR119 agonists

Bioorganic & medicinal chemistry, 2017-01, Vol.25 (1), p.254-260

2017

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Correction: Nitric oxide/paclitaxel micelles enhance anti-liver cancer effects and paclitaxel sensitivity by inducing ferroptosis, endoplasmic reticulum stress and pyroptosis

RSC advances, 2023-11, Vol.13 (49), p.34876-34876

2023

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Design, synthesis and antitumor activity of novel thiophene-pyrimidine derivatives as EGFR inhibitors overcoming T790M and L858R/T790M mutations

European journal of medicinal chemistry, 2020-10, Vol.203, p.112511, Article 112511

2020

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Novel 2,6-disubstituted benzofuran-3-one analogues improve cerebral ischemia/reperfusion injury via neuroprotective and antioxidative effects

Bioorganic chemistry, 2023-03, Vol.132, p.106346-106346, Article 106346

2023

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Coumarin-dithiocarbamate hybrids as novel multitarget AChE and MAO-B inhibitors against Alzheimer’s disease: Design, synthesis and biological evaluation

Bioorganic chemistry, 2018-12, Vol.81, p.512-528

2018

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Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors for the treatment of non-small cell lung cancer: a patent review (2014-present)

Synthesis of Halogenated 1,5-Diarylimidazoles and Their Inhibitory Effects on LPS-Induced PGE2 Production in RAW 264.7 Cells

Design, Synthesis, and Biological Evaluation of Novel Thienopyrimidine Derivatives as PI3Kα Inhibitors

Design, Synthesis and Biological Evaluation of Novel Phenylsulfonylurea Derivatives as PI3K/mTOR Dual Inhibitors

Optimisation of novel 4, 8-disubstituted dihydropyrimido[5,4-b][1,4]oxazine derivatives as potent GPR 119 agonists

Effects of novel pyrrolomycin MP1 in MYCN amplified chemoresistant neuroblastoma cell lines alone and combined with temsirolimus

Synthesis, Biological Evaluation, and Mode of Action of Pulsatilla Saponin D Derivatives as Promising Anticancer Agents

Discovery of Triazolo-pyridazine/-pyrimidine Derivatives Bearing Aromatic (Heterocycle)-Coupled Azole Units as Class II c‑Met Inhibitors

Discovery of novel quinazoline derivatives bearing semicarbazone moiety as potent EGFR kinase inhibitors

The new opportunities in medicinal chemistry of fourth-generation EGFR inhibitors to overcome C797S mutation

Synthesis of 1,5-diarylhaloimidazole analogs and their inhibitory activities against PGE2 production from LPS-treated RAW 264.7 cells

Synthesis and biological evaluation of pyrimidine derivatives with diverse azabicyclic ether/amine as novel GPR119 agonist

Research progress of PROTACs for neurodegenerative diseases therapy

GPR119 agonists for the treatment of type 2 diabetes: an updated patent review (2014-present)

Discovery of thiapyran-pyrimidine derivatives as potential EGFR inhibitors

Design, synthesis and 3D-QSAR analysis of novel thiopyranopyrimidine derivatives as potential antitumor agents inhibiting A549 and Hela cancer cells

Discovery of Selective Proteolysis-Targeting Chimera Degraders Targeting PTP1B as Long-Term Hypoglycemic Agents

Nitric oxide/paclitaxel micelles enhance anti-liver cancer effects and paclitaxel sensitivity by inducing ferroptosis, endoplasmic reticulum stress and pyroptosis

Evaluation of novel paclitaxel-loaded NO-donating polymeric micelles for an improved therapy for gastroenteric tumor

Design and synthesis of novel pyrimido[5,4-d]pyrimidine derivatives as GPR119 agonist for treatment of type 2 diabetes

Novel 5-nitropyrimidine derivatives bearing endo-azabicyclic alcohols/amines as potent GPR119 agonists

Correction: Nitric oxide/paclitaxel micelles enhance anti-liver cancer effects and paclitaxel sensitivity by inducing ferroptosis, endoplasmic reticulum stress and pyroptosis

Design, synthesis and antitumor activity of novel thiophene-pyrimidine derivatives as EGFR inhibitors overcoming T790M and L858R/T790M mutations

Novel 2,6-disubstituted benzofuran-3-one analogues improve cerebral ischemia/reperfusion injury via neuroprotective and antioxidative effects

Coumarin-dithiocarbamate hybrids as novel multitarget AChE and MAO-B inhibitors against Alzheimer’s disease: Design, synthesis and biological evaluation

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