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Disease‐specific interactome alterations via epichaperomics: the case for Alzheimer’s disease

The FEBS journal, 2022-04, Vol.289 (8), p.2047-2066

2022

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Causative role of PDLIM2 epigenetic repression in lung cancer and therapeutic resistance

Nature communications, 2019-11, Vol.10 (1), p.5324-13, Article 5324

2019

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Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2

Nature chemical biology, 2013-11, Vol.9 (11), p.677

2013

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The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction

Nature communications, 2020-01, Vol.11 (1), p.319-19, Article 319

2020

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Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation

Nature communications, 2023-06, Vol.14 (1), p.3742-3742, Article 3742

2023

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Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system

Nature communications, 2021-08, Vol.12 (1), p.4669-4669, Article 4669

2021

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Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone

Cell reports (Cambridge), 2020-06, Vol.31 (13), p.107840-107840, Article 107840

2020

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The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis

Blood, 2011-02, Vol.117 (5), p.1652-1661

2011

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PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation

Blood, 2009-04, Vol.113 (18), p.4370-4380

2009

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DNA Methylation-Dependent Repression of PDZ-LIM Domain-Containing Protein 2 in Colon Cancer and Its Role as a Potential Therapeutic Target

Cancer research (Chicago, Ill.), 2010-03, Vol.70 (5), p.1766-1772

2010

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Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer

Communications biology, 2021-11, Vol.4 (1), p.1333-20, Article 1333

2021

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Human T-Cell Leukemia Virus Type I-Mediated Repression of PDZ-LIM Domain-Containing Protein 2 Involves DNA Methylation But Independent of the Viral Oncoprotein Tax

Neoplasia (New York, N.Y.), 2009-10, Vol.11 (10), p.1036-1041

2009

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Affinity Purification Probes of Potential Use To Investigate the Endogenous Hsp70 Interactome in Cancer

ACS chemical biology, 2014-08, Vol.9 (8), p.1698-1705

2014

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Effect of μ-Opioid Receptor Gene Polymorphisms on Heroin-Induced Subjective Responses in a Chinese Population

Biological psychiatry (1969), 2007-06, Vol.61 (11), p.1244-1251

2007

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How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view

Structure (London), 2023-08, Vol.31 (8), p.987-1004.e8

2023

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The effect of dopamine D2, D5 receptor and transporter (SLC6A3) polymorphisms on the cue-elicited heroin craving in Chinese

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2006-04, Vol.141B (3), p.269-273

2006

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Chaperome Networks – Redundancy and Implications for Cancer Treatment

Advances in experimental medicine and biology, 2020, Vol.1243, p.87-99

2020

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Coordination of the canonical and noncanonical IKK/NF-κB signaling pathways in HTLV-I Tax-mediated tumorigenesis

Retrovirology, 2011-06, Vol.8 (S1), p.A157-A157, Article A157

2011

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Hsp90 regulates processing of NF-κB2 p100 involving protection of NF-κB-inducing kinase (NIK) from autophagy-mediated degradation

Cell research, 2007-06, Vol.17 (6), p.520-530

2007

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A Chemical Biology Approach to the Chaperome in Cancer-HSP90 and Beyond

Cold Spring Harbor perspectives in biology, 2020-04, Vol.12 (4), p.a034116

2020

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Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IκB kinase (IKK)

Cell research, 2006-11, Vol.16 (11), p.895-901

2006

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Targeting Autophagic Regulation of NF-kappaB in HTLV-I Transformed Cells by Geldanamycin: Implications for Therapeutic Interventions

Autophagy, 2007-11, Vol.3 (6), p.600-603

2007

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Epigenetic Repression of PDZ-LIM Domain-containing Protein 2: IMPLICATIONS FOR THE BIOLOGY AND TREATMENT OF BREAST CANCER

The Journal of biological chemistry, 2010-04, Vol.285 (16), p.11786-11792

2010

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Disease‐specific interactome alterations via epichaperomics: the case for Alzheimer’s disease

Causative role of PDLIM2 epigenetic repression in lung cancer and therapeutic resistance

Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2

The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction

Paradigms for Precision Medicine in Epichaperome Cancer Therapy

Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation

Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system

Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone

The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis

PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation

DNA Methylation-Dependent Repression of PDZ-LIM Domain-Containing Protein 2 in Colon Cancer and Its Role as a Potential Therapeutic Target

Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer

Human T-Cell Leukemia Virus Type I-Mediated Repression of PDZ-LIM Domain-Containing Protein 2 Involves DNA Methylation But Independent of the Viral Oncoprotein Tax

Affinity Purification Probes of Potential Use To Investigate the Endogenous Hsp70 Interactome in Cancer

Effect of μ-Opioid Receptor Gene Polymorphisms on Heroin-Induced Subjective Responses in a Chinese Population

How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view

The effect of dopamine D2, D5 receptor and transporter (SLC6A3) polymorphisms on the cue-elicited heroin craving in Chinese

Chaperome Networks – Redundancy and Implications for Cancer Treatment

The epichaperome is an integrated chaperome network that facilitates tumour survival

Coordination of the canonical and noncanonical IKK/NF-κB signaling pathways in HTLV-I Tax-mediated tumorigenesis

Hsp90 regulates processing of NF-κB2 p100 involving protection of NF-κB-inducing kinase (NIK) from autophagy-mediated degradation

A Chemical Biology Approach to the Chaperome in Cancer-HSP90 and Beyond

Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IκB kinase (IKK)

Targeting Autophagic Regulation of NF-kappaB in HTLV-I Transformed Cells by Geldanamycin: Implications for Therapeutic Interventions

Epigenetic Repression of PDZ-LIM Domain-containing Protein 2: IMPLICATIONS FOR THE BIOLOGY AND TREATMENT OF BREAST CANCER

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