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Engineering of a novel anti-CD40L domain antibody for treatment of autoimmune diseases

The Journal of immunology (1950), 2014-05, Vol.192 (9), p.4083-4092

2014

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Therapeutic Activity of Agonistic, Human Anti-CD40 Monoclonal Antibodies Requires Selective FcγR Engagement

Cancer cell, 2016-06, Vol.29 (6), p.820-831

2016

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Investigation of anomalous charge variant profile reveals discrete pH-dependent conformations and conformation-dependent charge states within the CDR3 loop of a therapeutic mAb

mAbs, 2020-01, Vol.12 (1), p.1763138-1763138

2020

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Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope

Journal of molecular biology, 2016-07, Vol.428 (14), p.2860-2879

2016

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The structure of the death receptor 4-TNF-related apoptosis-inducing ligand (DR4-TRAIL) complex

Acta crystallographica. Section F, Structural biology communications, 2015-10, Vol.71 (10), p.1273-1281

2015

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IL-2/CD25: A Long-Acting Fusion Protein That Promotes Immune Tolerance by Selectively Targeting the IL-2 Receptor on Regulatory T Cells

The Journal of immunology (1950), 2018-11, Vol.201 (9), p.2579-2592

2018

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Solution structures of the SH3 domains from Shank scaffold proteins and their interactions with Cav1.3 calcium channels

FEBS letters, 2018-08, Vol.592 (16), p.2786-2797

2018

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Calcium-dependent and -independent Binding of Soybean Calmodulin Isoforms to the Calmodulin Binding Domain of Tobacco MAPK Phosphatase-1

The Journal of biological chemistry, 2007-03, Vol.282 (9), p.6031-6042

2007

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Metal Ion Binding Properties and Conformational States of Calcium- and Integrin-Binding Protein

Biochemistry (Easton), 2004-03, Vol.43 (9), p.2558-2568

2004

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The Solution Structures of Two Soybean Calmodulin Isoforms Provide a Structural Basis for Their Selective Target Activation Properties

The Journal of biological chemistry, 2008-05, Vol.283 (21), p.14619-14628

2008

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Characterization and quantification of histidine degradation in therapeutic protein formulations by size exclusion-hydrophilic interaction two dimensional-liquid chromatography with stable-isotope labeling mass spectrometry

Journal of Chromatography A, 2015-12, Vol.1426, p.133-139

2015

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Calmodulin's flexibility allows for promiscuity in its interactions with target proteins and peptides

Molecular biotechnology, 2004-05, Vol.27 (1), p.33-57

2004

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Bioavailability of protein therapeutics in rats following inhalation exposure: Relevance to occupational exposure limit calculations

Regulatory toxicology and pharmacology, 2018-12, Vol.100, p.35-44

2018

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Thermodynamic characterization of the interactions between the immunoregulatory proteins osteopontin and lactoferrin

Molecular immunology, 2009-07, Vol.46 (11), p.2395-2402

2009

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Application of a Kosmotrope-Based Solubility Assay to Multiple Protein Therapeutic Classes Indicates Broad Use as a High-Throughput Screen for Protein Therapeutic Aggregation Propensity

Journal of pharmaceutical sciences, 2013-08, Vol.102 (8), p.2424-2439

2013

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Protein conformational changes studied by diffusion NMR spectroscopy: Application to helix‐loop‐helix calcium binding proteins

Protein science, 2003-02, Vol.12 (2), p.228-236

2003

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Characterization of Mauritian Cynomolgus Macaque FcγR Alleles Using Long-Read Sequencing

The Journal of immunology (1950), 2019-01, Vol.202 (1), p.151-159

2019

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Structurally Homologous Binding of Plant Calmodulin Isoforms to the Calmodulin-binding Domain of Vacuolar Calcium-ATPase

The Journal of biological chemistry, 2004-02, Vol.279 (9), p.7698-7707

2004

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Calmodulin has the Potential to Function as a Ca2+-Dependent Adaptor Protein

Plant signaling & behavior, 2007-09, Vol.2 (5), p.354-357

2007

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Thermodynamic Effects of Noncoded and Coded Methionine Substitutions in Calmodulin

Biophysical journal, 2009-02, Vol.96 (4), p.1495-1507

2009

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Comparison of Ensemble and Single Molecule Methods for Particle Characterization and Binding Analysis of a PEGylated Single-Domain Antibody

Journal of pharmaceutical sciences, 2015-12, Vol.104 (12), p.4015-4024

2015

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The Interaction between Calcium- and Integrin-binding Protein 1 and the αIIb Integrin Cytoplasmic Domain Involves a Novel C-terminal Displacement Mechanism

The Journal of biological chemistry, 2006-09, Vol.281 (36), p.26455-26464

2006

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Calcium‐ and magnesium‐dependent interactions between calcium‐ and integrin‐binding protein and the integrin αIIb cytoplasmic domain

Protein science, 2005-06, Vol.14 (6), p.1429-1437

2005

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Reversible and pH-dependent weak drug-excipient binding does not affect oral bioavailability of high dose drugs

Journal of pharmacy and pharmacology, 2012-04, Vol.64 (4), p.553-565

2012

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Engineering of a novel anti-CD40L domain antibody for treatment of autoimmune diseases

Therapeutic Activity of Agonistic, Human Anti-CD40 Monoclonal Antibodies Requires Selective FcγR Engagement

Investigation of anomalous charge variant profile reveals discrete pH-dependent conformations and conformation-dependent charge states within the CDR3 loop of a therapeutic mAb

Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope

The structure of the death receptor 4-TNF-related apoptosis-inducing ligand (DR4-TRAIL) complex

IL-2/CD25: A Long-Acting Fusion Protein That Promotes Immune Tolerance by Selectively Targeting the IL-2 Receptor on Regulatory T Cells

Solution structures of the SH3 domains from Shank scaffold proteins and their interactions with Cav1.3 calcium channels

Calcium-dependent and -independent Binding of Soybean Calmodulin Isoforms to the Calmodulin Binding Domain of Tobacco MAPK Phosphatase-1

Metal Ion Binding Properties and Conformational States of Calcium- and Integrin-Binding Protein

The Solution Structures of Two Soybean Calmodulin Isoforms Provide a Structural Basis for Their Selective Target Activation Properties

Characterization and quantification of histidine degradation in therapeutic protein formulations by size exclusion-hydrophilic interaction two dimensional-liquid chromatography with stable-isotope labeling mass spectrometry

Calmodulin's flexibility allows for promiscuity in its interactions with target proteins and peptides

Bioavailability of protein therapeutics in rats following inhalation exposure: Relevance to occupational exposure limit calculations

Thermodynamic characterization of the interactions between the immunoregulatory proteins osteopontin and lactoferrin

Application of a Kosmotrope-Based Solubility Assay to Multiple Protein Therapeutic Classes Indicates Broad Use as a High-Throughput Screen for Protein Therapeutic Aggregation Propensity

Protein conformational changes studied by diffusion NMR spectroscopy: Application to helix‐loop‐helix calcium binding proteins

Characterization of Mauritian Cynomolgus Macaque FcγR Alleles Using Long-Read Sequencing

Structurally Homologous Binding of Plant Calmodulin Isoforms to the Calmodulin-binding Domain of Vacuolar Calcium-ATPase

Calmodulin has the Potential to Function as a Ca2+-Dependent Adaptor Protein

Thermodynamic Effects of Noncoded and Coded Methionine Substitutions in Calmodulin

Comparison of Ensemble and Single Molecule Methods for Particle Characterization and Binding Analysis of a PEGylated Single-Domain Antibody

The Interaction between Calcium- and Integrin-binding Protein 1 and the αIIb Integrin Cytoplasmic Domain Involves a Novel C-terminal Displacement Mechanism

Calcium‐ and magnesium‐dependent interactions between calcium‐ and integrin‐binding protein and the integrin αIIb cytoplasmic domain

A fibronectin scaffold approach to bispecific inhibitors of epidermal growth factor receptor and insulin-like growth factor-I receptor

Reversible and pH-dependent weak drug-excipient binding does not affect oral bioavailability of high dose drugs

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