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Application of machine learning techniques to the analysis and prediction of drug pharmacokinetics

Journal of controlled release, 2022-12, Vol.352, p.961-969

2022

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Application of machine learning techniques in population pharmacokinetics/pharmacodynamics modeling

Drug metabolism and pharmacokinetics, 2024-06, Vol.56, p.101004, Article 101004

2024

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Prediction of HIV drug resistance based on the 3D protein structure: Proposal of molecular field mapping

PloS one, 2021-08, Vol.16 (8), p.e0255693

2021

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The Application of the in-Situ Hyperthermia Emission from Acoustic Nanodroplets for Theranostic Dual-Imaging and Antitumor Modalities

Biological and Pharmaceutical Bulletin, 2020/07/01, Vol.43(7), pp.1141-1145

2020

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Evaluation of the Theranostic Potential of Perfluorohexane-Based Acoustic Nanodroplets

Biological and Pharmaceutical Bulletin, 2019/12/01, Vol.42(12), pp.2038-2044

2019

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In Vitro Evaluation of Inhibitory Effect of Nuclear Factor-KappaB Activity by Small Interfering RNA on Pro-tumor Characteristics of M2-Like Macrophages

Biological and Pharmaceutical Bulletin, 2014/01/01, Vol.37(1), pp.137-144

2014

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Intestinal Permeability of Drugs in Caco-2 Cells Cultured in Microfluidic Devices

Biological and Pharmaceutical Bulletin, 2022/09/01, Vol.45(9), pp.1246-1253

2022

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Anti-MUC1 Aptamer/Negatively Charged Amino Acid Dendrimer Conjugates for Targeted Delivery to Human Lung Adenocarcinoma A549 Cells

Biological and Pharmaceutical Bulletin, 2016/10/01, Vol.39(10), pp.1734-1738

2016

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Binding and structure-kinetic relationship analysis of selective TLR4-targeted immunosuppressive self-assembling heparin nanoparticles

International journal of pharmaceutics, 2018-12, Vol.552 (1-2), p.76-83

2018

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Application of perfluoropolyether elastomers in microfluidic drug metabolism assays

International journal of pharmaceutics, 2022-11, Vol.627, p.122253-122253, Article 122253

2022

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Anti-inflammatory Effect of Self-assembling Glycol-Split Glycosaminoglycan-Stearylamine Conjugates in Lipopolysaccharide-Stimulated Macrophages

Biological and Pharmaceutical Bulletin, 2017/04/01, Vol.40(4), pp.540-545

2017

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Efficient Gene Transfection by Histidine-Modified Chitosan through Enhancement of Endosomal Escape

Bioconjugate chemistry, 2010-06, Vol.21 (6), p.1087-1095

2010

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Dynamic changes in gene-to-gene regulatory networks in response to SARS-CoV-2 infection

Scientific reports, 2021-05, Vol.11 (1), p.11241-11241, Article 11241

2021

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Modeling of rifampicin-induced CYP3A4 activation dynamics for the prediction of clinical drug-drug interactions from in vitro data

PloS one, 2013-09, Vol.8 (9), p.e70330

2013

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In Silico Approaches for Predicting ADME Properties of Drugs

DRUG METABOLISM AND PHARMACOKINETICS, 2004, Vol.19 (5), p.327-338

2004

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Cytosolic Ca2+-dependent Ca2+ release activity primarily determines the ER Ca2+ level in cells expressing the CPVT-linked mutant RYR2

The Journal of general physiology, 2022-09, Vol.154 (9), p.1

2022

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The Role of Inter-segmental Differences in P-glycoprotein Expression and Activity along the Rat Small Intestine in Causing the Double-peak Phenomenon of Substrate Plasma Concentration

DRUG METABOLISM AND PHARMACOKINETICS, 2013, Vol.28 (2), p.98-103

2013

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A model-based comparative meta-analysis of the efficacy of dolutegravir-based and efavirenz-based regimens in HIV-infected patients

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2019-09, Vol.25 (9), p.687-694

2019

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Efficient targeting to alveolar macrophages by intratracheal administration of mannosylated liposomes in rats

Journal of controlled release, 2008-01, Vol.125 (2), p.121-130

2008

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An Evolutionary Search Algorithm for Covariate Models in Population Pharmacokinetic Analysis

Journal of pharmaceutical sciences, 2017-09, Vol.106 (9), p.2407-2411

2017

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Artificial neural network analysis for predicting human percutaneous absorption taking account of vehicle properties

The Journal of Toxicological Sciences, 2015/04/01, Vol.40(2), pp.277-294

2015

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Modeling and Prediction of Solvent Effect on Human Skin Permeability using Support Vector Regression and Random Forest

Pharmaceutical research, 2015-11, Vol.32 (11), p.3604-3617

2015

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Photothermic regulation of gene expression triggered by laser-induced carbon nanohorns

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (19), p.7523-7528

2012

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Sedative Effects of Inhaled Benzylacetone and Structural Features Contributing to Its Activity

Biological and Pharmaceutical Bulletin, 2013/09/01, Vol.36(9), pp.1474-1481

2013

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CREB is a potential marker associated with drug-induced liver injury: Identification and validation through transcriptome database analysis

The Journal of Toxicological Sciences, 2022, Vol.47(8), pp.337-348

2022

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Application of machine learning techniques to the analysis and prediction of drug pharmacokinetics

Application of machine learning techniques in population pharmacokinetics/pharmacodynamics modeling

Prediction of HIV drug resistance based on the 3D protein structure: Proposal of molecular field mapping

The Application of the in-Situ Hyperthermia Emission from Acoustic Nanodroplets for Theranostic Dual-Imaging and Antitumor Modalities

Evaluation of the Theranostic Potential of Perfluorohexane-Based Acoustic Nanodroplets

In Vitro Evaluation of Inhibitory Effect of Nuclear Factor-KappaB Activity by Small Interfering RNA on Pro-tumor Characteristics of M2-Like Macrophages

Intestinal Permeability of Drugs in Caco-2 Cells Cultured in Microfluidic Devices

Anti-MUC1 Aptamer/Negatively Charged Amino Acid Dendrimer Conjugates for Targeted Delivery to Human Lung Adenocarcinoma A549 Cells

Binding and structure-kinetic relationship analysis of selective TLR4-targeted immunosuppressive self-assembling heparin nanoparticles

Application of perfluoropolyether elastomers in microfluidic drug metabolism assays

Anti-inflammatory Effect of Self-assembling Glycol-Split Glycosaminoglycan-Stearylamine Conjugates in Lipopolysaccharide-Stimulated Macrophages

Efficient Gene Transfection by Histidine-Modified Chitosan through Enhancement of Endosomal Escape

Dynamic changes in gene-to-gene regulatory networks in response to SARS-CoV-2 infection

Modeling of rifampicin-induced CYP3A4 activation dynamics for the prediction of clinical drug-drug interactions from in vitro data

In Silico Approaches for Predicting ADME Properties of Drugs

Cytosolic Ca2+-dependent Ca2+ release activity primarily determines the ER Ca2+ level in cells expressing the CPVT-linked mutant RYR2

The Role of Inter-segmental Differences in P-glycoprotein Expression and Activity along the Rat Small Intestine in Causing the Double-peak Phenomenon of Substrate Plasma Concentration

A model-based comparative meta-analysis of the efficacy of dolutegravir-based and efavirenz-based regimens in HIV-infected patients

Efficient targeting to alveolar macrophages by intratracheal administration of mannosylated liposomes in rats

An Evolutionary Search Algorithm for Covariate Models in Population Pharmacokinetic Analysis

Artificial neural network analysis for predicting human percutaneous absorption taking account of vehicle properties

Modeling and Prediction of Solvent Effect on Human Skin Permeability using Support Vector Regression and Random Forest

Photothermic regulation of gene expression triggered by laser-induced carbon nanohorns

Sedative Effects of Inhaled Benzylacetone and Structural Features Contributing to Its Activity

CREB is a potential marker associated with drug-induced liver injury: Identification and validation through transcriptome database analysis

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