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SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition

Cell metabolism, 2020-09, Vol.32 (3), p.404-419.e6

2020

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Podocytes maintain high basal levels of autophagy independent of mtor signaling

Autophagy, 2020-11, Vol.16 (11), p.1932-1948

2020

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Obesity-Mediated Autophagy Insufficiency Exacerbates Proteinuria-induced Tubulointerstitial Lesions

Journal of the American Society of Nephrology, 2013-11, Vol.24 (11), p.1769-1781

2013

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Improvement in Decline Rate of Estimated Glomerular Filtration Rate after Febuxostat Treatment in a Fabry Disease Patient with Enzyme Replacement Therapy-resistant Proteinuria

Internal Medicine, 2022/10/15, Vol.61(20), pp.3077-3081

2022

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Role of dietary amino acid balance in diet restriction‐mediated lifespan extension, renoprotection, and muscle weakness in aged mice

Aging cell, 2018-08, Vol.17 (4), p.e12796-n/a

2018

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A reciprocal regulation of spermidine and autophagy in podocytes maintains the filtration barrier

Kidney international, 2020-12, Vol.98 (6), p.1434-1448

2020

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Inhibition of mitochondrial fission protects podocytes from albumin-induced cell damage in diabetic kidney disease

Biochimica et biophysica acta. Molecular basis of disease, 2022-05, Vol.1868 (5), p.166368-166368, Article 166368

2022

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Protein O-GlcNAcylation Is Essential for the Maintenance of Renal Energy Homeostasis and Function via Lipolysis during Fasting and Diabetes

Journal of the American Society of Nephrology, 2019-06, Vol.30 (6), p.962-978

2019

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Cisplatin Nephrotoxicity Is Critically Mediated by the Availability of BECLIN1

International journal of molecular sciences, 2024-02, Vol.25 (5), p.2560

2024

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Limited effects of systemic or renal lipoprotein lipase deficiency on renal physiology and diseases

Biochemical and biophysical research communications, 2022-09, Vol.620, p.15-20

2022

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AIF1L regulates actomyosin contractility and filopodial extensions in human podocytes

PloS one, 2018-07, Vol.13 (7), p.e0200487-e0200487

2018

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Autophagy: Emerging Therapeutic Target for Diabetic Nephropathy

Seminars in nephrology, 2014, Vol.34 (1), p.9-16

2014

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BECLIN1 Is Essential for Podocyte Secretory Pathways Mediating VEGF Secretion and Podocyte-Endothelial Crosstalk

International journal of molecular sciences, 2022-03, Vol.23 (7), p.3825

2022

Volltextzugriff (PDF)

Establishment of a novel mouse model of renal artery coiling-based chronic hypoperfusion-related kidney injury

Biochemistry and biophysics reports, 2024-03, Vol.37, p.101607-101607, Article 101607

2024

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The Role of Autophagy in the Pathogenesis of Diabetic Nephropathy

Journal of Diabetes Research, 2013-01, Vol.2013, p.193757-9

2013

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Emerging Pathophysiological Roles of Ketone Bodies

Physiology (Bethesda, Md.), 2024-05, Vol.39 (3), p.0

2024

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Safety and efficacy of skin patches containing loxoprofen sodium in diabetic patients with overt nephropathy

Clinical and experimental nephrology, 2014-06, Vol.18 (3), p.487-491

2014

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A novel therapeutic target for kidney diseases: Lessons learned from starvation response

Pharmacology & therapeutics (Oxford), 2024-02, Vol.254, p.108590-108590, Article 108590

2024

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Fructose overconsumption accelerates renal dysfunction with aberrant glomerular endothelial-mesangial cell interactions in db/db mice

Biochimica et biophysica acta. Molecular basis of disease, 2024-04, Vol.1870 (4), p.167074-167074, Article 167074

2024

Volltextzugriff (PDF)

Ketone bodies: A double‐edged sword for mammalian life span

Aging cell, 2023-06, Vol.22 (6), p.e13833-n/a

2023

Volltextzugriff (PDF)

Ketone Body Metabolism in Diabetic Kidney Disease

Kidney360, 2024-02, Vol.5 (2), p.320-326

2024

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Protective role of podocyte autophagy against glomerular endothelial dysfunction in diabetes

Biochemical and biophysical research communications, 2020-04, Vol.525 (2), p.319-325

2020

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O-linked β-N-acetylglucosamine modification of proteins is essential for foot process maturation and survival in podocytes

Nephrology, dialysis, transplantation, 2017-09, Vol.32 (9), p.1477-1487

2017

Volltextzugriff (PDF)

Improvement in Estimated Glomerular Filtration Rate Decline Rate after Febuxostat Treatment in a Fabry Disease Patient with Enzyme Replacement Therapy-resistant Proteinuria

Internal Medicine, 2022, pp.8993-21

2022

Volltextzugriff (PDF)

SP430Potential role for ketone body metabolism in an SGLT2 inhibitor-mediated anti-albuminuric effect in type 2 diabetic db/db mice

Nephrology, dialysis, transplantation, 2019-06, Vol.34 (Supplement_1)

2019

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SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition

Podocytes maintain high basal levels of autophagy independent of mtor signaling

Obesity-Mediated Autophagy Insufficiency Exacerbates Proteinuria-induced Tubulointerstitial Lesions

Improvement in Decline Rate of Estimated Glomerular Filtration Rate after Febuxostat Treatment in a Fabry Disease Patient with Enzyme Replacement Therapy-resistant Proteinuria

Role of dietary amino acid balance in diet restriction‐mediated lifespan extension, renoprotection, and muscle weakness in aged mice

A reciprocal regulation of spermidine and autophagy in podocytes maintains the filtration barrier

Inhibition of mitochondrial fission protects podocytes from albumin-induced cell damage in diabetic kidney disease

Protein O-GlcNAcylation Is Essential for the Maintenance of Renal Energy Homeostasis and Function via Lipolysis during Fasting and Diabetes

Cisplatin Nephrotoxicity Is Critically Mediated by the Availability of BECLIN1

Limited effects of systemic or renal lipoprotein lipase deficiency on renal physiology and diseases

AIF1L regulates actomyosin contractility and filopodial extensions in human podocytes

Autophagy: Emerging Therapeutic Target for Diabetic Nephropathy

BECLIN1 Is Essential for Podocyte Secretory Pathways Mediating VEGF Secretion and Podocyte-Endothelial Crosstalk

Establishment of a novel mouse model of renal artery coiling-based chronic hypoperfusion-related kidney injury

The Role of Autophagy in the Pathogenesis of Diabetic Nephropathy

Emerging Pathophysiological Roles of Ketone Bodies

Safety and efficacy of skin patches containing loxoprofen sodium in diabetic patients with overt nephropathy

A novel therapeutic target for kidney diseases: Lessons learned from starvation response

Fructose overconsumption accelerates renal dysfunction with aberrant glomerular endothelial-mesangial cell interactions in db/db mice

Ketone bodies: A double‐edged sword for mammalian life span

Ketone Body Metabolism in Diabetic Kidney Disease

Protective role of podocyte autophagy against glomerular endothelial dysfunction in diabetes

O-linked β-N-acetylglucosamine modification of proteins is essential for foot process maturation and survival in podocytes

Improvement in Estimated Glomerular Filtration Rate Decline Rate after Febuxostat Treatment in a Fabry Disease Patient with Enzyme Replacement Therapy-resistant Proteinuria

SP430Potential role for ketone body metabolism in an SGLT2 inhibitor-mediated anti-albuminuric effect in type 2 diabetic db/db mice

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