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Interference by doxorubicin with DNA unwinding in MCF-7 breast tumor cells

Molecular pharmacology, 1994-04, Vol.45 (4), p.649-656

1994

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Pro-oxidant and antioxidant mechanisms of etoposide in HL-60 cells : Role of myeloperoxidase

Cancer research (Chicago, Ill.), 2001-11, Vol.61 (21), p.7777-7784

2001

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Cytoplasmic metallothionein overexpression protects NIH 3T3 cells from tert-butyl hydroperoxide toxicity

The Journal of biological chemistry, 1994-05, Vol.269 (21), p.15238-15243

1994

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Metallothionein Protects Against the Cytotoxic and DNA-Damaging Effects of Nitric Oxide

Proceedings of the National Academy of Sciences - PNAS, 1995-05, Vol.92 (10), p.4452-4456

1995

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Lipid Antioxidant, Etoposide, Inhibits Phosphatidylserine Externalization and Macrophage Clearance of Apoptotic Cells by Preventing Phosphatidylserine Oxidation

The Journal of biological chemistry, 2004-02, Vol.279 (7), p.6056-6064

2004

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Altered stability of etoposide-induced topoisomerase II-DNA complexes in resistant human leukaemia K562 cells

British journal of cancer, 1994-04, Vol.69 (4), p.687-697

1994

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Mutational inactivation of the p53 gene in the human erythroid leukemic K562 cell line

Leukemia research, 1993-12, Vol.17 (12), p.1045-1050

1993

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The catalytic DNA topoisomerase II inhibitor dexrazoxane (ICRF-187) induces endopolyploidy in Chinese hamster ovary cells

The Journal of pharmacology and experimental therapeutics, 2000-11, Vol.295 (2), p.474

2000

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Atypical multiple drug resistance in a human leukemic cell line selected for resistance to Teniposide (VM-26)

Cancer research (Chicago, Ill.), 1987-03, Vol.47 (5), p.1297-1301

1987

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Characterization of a Chinese hamster ovary cell line with acquired resistance to the bisdioxopiperazine dexrazoxane (ICRF-187) catalytic inhibitor of topoisomerase II

Biochemical pharmacology, 1997-06, Vol.53 (12), p.1843-1853

1997

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Altered gene expression in human leukemia K562 cells selected for resistance to etoposide

Biochemical pharmacology, 1993-12, Vol.46 (11), p.2007-2020

1993

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Differential induction of etoposide-mediated apoptosis in human leukemia HL-60 and K562 cells

Molecular pharmacology, 1994-10, Vol.46 (4), p.605-611

1994

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Collateral sensitivity to the bisdioxopiperazine dexrazoxane (ICRF-187) in etoposide (VP-16)-resistant human leukemia K562 cells

Biochemical pharmacology, 1996-08, Vol.52 (4), p.635-642

1996

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The histone deacetylase inhibitor sodium butyrate induces DNA topoisomerase II alpha expression and confers hypersensitivity to etoposide in human leukemic cell lines

Molecular cancer therapeutics, 2001-12, Vol.1 (2), p.121

2001

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Genesis of discrete higher order DNA fragments in apoptotic human prostatic carcinoma cells

Molecular pharmacology, 1996-02, Vol.49 (2), p.244-252

1996

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Induction of apoptosis in murine and human neuroblastoma cell lines by the enediyne natural product neocarzinostatin

The Journal of pharmacology and experimental therapeutics, 1995-10, Vol.275 (1), p.479

1995

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The Catalytic DNA Topoisomerase II Inhibitor Dexrazoxane (ICRF-187) Induces Differentiation and Apoptosis in Human Leukemia K562 Cells

Molecular pharmacology, 2001-03, Vol.59 (3), p.453-461

2001

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Mechanism-Based Chemopreventive Strategies Against Etoposide-Induced Acute Myeloid Leukemia: Free Radical/Antioxidant Approach

Molecular pharmacology, 1999-09, Vol.56 (3), p.494-506

1999

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Antioxidant mechanisms of nitric oxide against iron-catalyzed oxidative stress in cells

Antioxidants & redox signaling, 2001-04, Vol.3 (2), p.189-202

2001

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Reduced phosphorylation of topoisomerase II in etoposide-resistant human leukemia K562 cells

Molecular pharmacology, 1994-07, Vol.46 (1), p.58-66

1994

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Mechanisms of Action and Reduced Cardiotoxicity of Pixantrone; a Topoisomerase II Targeting Agent with Cellular Selectivity for the Topoisomerase II Isoform

The Journal of pharmacology and experimental therapeutics, 2016-01, Vol.356 (2), p.397-409

2016

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Phenoxyl Radicals of Etoposide (VP-16) Can Directly Oxidize Intracellular Thiols: Protective Versus Damaging Effects of Phenolic Antioxidants

Toxicology and applied pharmacology, 1995-04, Vol.131 (2), p.277-288

1995

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Direct evidence for recycling of myeloperoxidase-catalyzed phenoxyl radicals of a vitamin E homologue, 2,2,5,7,8-pentamethyl-6-hydroxy chromane, by ascorbate/dihydrolipoate in living HL-60 cells

Biochimica et biophysica acta, 2003-03, Vol.1620 (1), p.72-84

2003

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Increased c- jun/AP-1 levels in etoposide-resistant human leukemia K562 cells

Biochemical pharmacology, 1994-08, Vol.48 (3), p.525-533

1994

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A QSAR study comparing the cytotoxicity and DNA topoisomerase II inhibitory effects of bisdioxopiperazine analogs of ICRF-187 (dexrazoxane)

Biochemical pharmacology, 1995-09, Vol.50 (7), p.953-958

1995

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Interference by doxorubicin with DNA unwinding in MCF-7 breast tumor cells

Pro-oxidant and antioxidant mechanisms of etoposide in HL-60 cells : Role of myeloperoxidase

Cytoplasmic metallothionein overexpression protects NIH 3T3 cells from tert-butyl hydroperoxide toxicity

Metallothionein Protects Against the Cytotoxic and DNA-Damaging Effects of Nitric Oxide

Lipid Antioxidant, Etoposide, Inhibits Phosphatidylserine Externalization and Macrophage Clearance of Apoptotic Cells by Preventing Phosphatidylserine Oxidation

Altered stability of etoposide-induced topoisomerase II-DNA complexes in resistant human leukaemia K562 cells

Mutational inactivation of the p53 gene in the human erythroid leukemic K562 cell line

The catalytic DNA topoisomerase II inhibitor dexrazoxane (ICRF-187) induces endopolyploidy in Chinese hamster ovary cells

Atypical multiple drug resistance in a human leukemic cell line selected for resistance to Teniposide (VM-26)

Characterization of a Chinese hamster ovary cell line with acquired resistance to the bisdioxopiperazine dexrazoxane (ICRF-187) catalytic inhibitor of topoisomerase II

Altered gene expression in human leukemia K562 cells selected for resistance to etoposide

Differential induction of etoposide-mediated apoptosis in human leukemia HL-60 and K562 cells

Collateral sensitivity to the bisdioxopiperazine dexrazoxane (ICRF-187) in etoposide (VP-16)-resistant human leukemia K562 cells

The histone deacetylase inhibitor sodium butyrate induces DNA topoisomerase II alpha expression and confers hypersensitivity to etoposide in human leukemic cell lines

Genesis of discrete higher order DNA fragments in apoptotic human prostatic carcinoma cells

Induction of apoptosis in murine and human neuroblastoma cell lines by the enediyne natural product neocarzinostatin

The Catalytic DNA Topoisomerase II Inhibitor Dexrazoxane (ICRF-187) Induces Differentiation and Apoptosis in Human Leukemia K562 Cells

Mechanism-Based Chemopreventive Strategies Against Etoposide-Induced Acute Myeloid Leukemia: Free Radical/Antioxidant Approach

Antioxidant mechanisms of nitric oxide against iron-catalyzed oxidative stress in cells

Reduced phosphorylation of topoisomerase II in etoposide-resistant human leukemia K562 cells

Mechanisms of Action and Reduced Cardiotoxicity of Pixantrone; a Topoisomerase II Targeting Agent with Cellular Selectivity for the Topoisomerase II Isoform

Phenoxyl Radicals of Etoposide (VP-16) Can Directly Oxidize Intracellular Thiols: Protective Versus Damaging Effects of Phenolic Antioxidants

Direct evidence for recycling of myeloperoxidase-catalyzed phenoxyl radicals of a vitamin E homologue, 2,2,5,7,8-pentamethyl-6-hydroxy chromane, by ascorbate/dihydrolipoate in living HL-60 cells

Increased c- jun/AP-1 levels in etoposide-resistant human leukemia K562 cells

A QSAR study comparing the cytotoxicity and DNA topoisomerase II inhibitory effects of bisdioxopiperazine analogs of ICRF-187 (dexrazoxane)

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