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Mutations in the Phosphatidylinositol-3-Kinase Pathway Predict for Antitumor Activity of the Inhibitor PX-866 whereas Oncogenic Ras Is a Dominant Predictor for Resistance

Cancer research (Chicago, Ill.), 2009-01, Vol.69 (1), p.143-150

2009

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MAPK pathways in radiation responses

Oncogene, 2003-09, Vol.22 (37), p.5885-5896

2003

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Radiation-induced cell signaling: inside-out and outside-in

Molecular cancer therapeutics, 2007-03, Vol.6 (3), p.789-801

2007

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Sorafenib activates CD95 and promotes autophagy and cell death via Src family kinases in gastrointestinal tumor cells

Molecular cancer therapeutics, 2010-08, Vol.9 (8), p.2220-2231

2010

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Sorafenib Enhances Pemetrexed Cytotoxicity through an Autophagy-Dependent Mechanism in Cancer Cells

Cancer research (Chicago, Ill.), 2011-07, Vol.71 (14), p.4955-4967

2011

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Astrocyte Elevated Gene-1: A Novel Target for Human Glioma Therapy

Molecular cancer therapeutics, 2010-01, Vol.9 (1), p.79-88

2010

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Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner

Oncogene, 2003-02, Vol.22 (8), p.1164-1180

2003

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Sorafenib and Vorinostat Kill Colon Cancer Cells by CD95-Dependent and -Independent Mechanisms

Molecular pharmacology, 2009-08, Vol.76 (2), p.342-355

2009

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mda- 7/IL-24: A unique member of the IL-10 gene family promoting cancer-targeted toxicity

Cytokine & growth factor reviews, 2010-10, Vol.21 (5), p.381-391

2010

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Poly(ADP-ribose) polymerase 1 modulates the lethality of CHK1 inhibitors in carcinoma cells

Molecular pharmacology, 2010-11, Vol.78 (5), p.909-917

2010

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Vorinostat and Sorafenib Synergistically Kill Tumor Cells via FLIP Suppression and CD95 Activation

Clinical cancer research, 2008-09, Vol.14 (17), p.5385-5399

2008

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Inhibition of MCL-1 in breast cancer cells promotes cell death in vitro and in vivo

Cancer biology & therapy, 2010-11, Vol.10 (9), p.903-917

2010

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Inhibition of vimentin or β1 integrin reverts morphology of prostate tumor cells grown in laminin-rich extracellular matrix gels and reduces tumor growth in vivo

Molecular cancer therapeutics, 2009-03, Vol.8 (3), p.499-508

2009

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OSU-03012 suppresses GRP78/BiP expression that causes PERK-dependent increases in tumor cell killing

Cancer biology & therapy, 2012-02, Vol.13 (4), p.224-236

2012

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Sorafenib and HDAC inhibitors synergize to kill CNS tumor cells

Cancer biology & therapy, 2012-05, Vol.13 (7), p.567-574

2012

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Ionizing Radiation Causes a Dose-Dependent Release of Transforming Growth Factor α In vitro from Irradiated Xenografts and during Palliative Treatment of Hormone-Refractory Prostate Carcinoma

Clinical cancer research, 2004-09, Vol.10 (17), p.5724-5731

2004

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Lapatinib Resistance in HCT116 Cells Is Mediated by Elevated MCL-1 Expression and Decreased BAK Activation and Not by ERBB Receptor Kinase Mutation

Molecular pharmacology, 2008-09, Vol.74 (3), p.807-822

2008

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OSU-03012 Stimulates PKR-Like Endoplasmic Reticulum-Dependent Increases in 70-kDa Heat Shock Protein Expression, Attenuating Its Lethal Actions in Transformed Cells

Molecular pharmacology, 2008-04, Vol.73 (4), p.1168-1184

2008

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OSU-03012 Promotes Caspase-Independent but PERK-, Cathepsin B-, BID-, and AIF-Dependent Killing of Transformed Cells

Molecular pharmacology, 2006-08, Vol.70 (2), p.589-603

2006

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RLIP76 in Defense of Radiation Poisoning

International journal of radiation oncology, biology, physics, 2008-10, Vol.72 (2), p.553-561

2008

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PERK-dependent regulation of MDA-7/IL-24-induced autophagy in primary human glioma cells

Autophagy, 2008-05, Vol.4 (4), p.513-515

2008

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Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes

Hepatology (Baltimore, Md.), 2002-04, Vol.35 (4), p.779-789

2002

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RLIP76 is a major determinant of radiation sensitivity

Cancer research (Chicago, Ill.), 2005-07, Vol.65 (14), p.6022-6028

2005

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MDA-7/IL-24 as a cancer therapeutic: from bench to bedside

Anti-cancer drugs, 2010-09, Vol.21 (8), p.725-731

2010

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Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways

Oncogene, 2001-05, Vol.20 (25), p.3266-3280

2001

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Mutations in the Phosphatidylinositol-3-Kinase Pathway Predict for Antitumor Activity of the Inhibitor PX-866 whereas Oncogenic Ras Is a Dominant Predictor for Resistance

MAPK pathways in radiation responses

Radiation-induced cell signaling: inside-out and outside-in

Sorafenib activates CD95 and promotes autophagy and cell death via Src family kinases in gastrointestinal tumor cells

Sorafenib Enhances Pemetrexed Cytotoxicity through an Autophagy-Dependent Mechanism in Cancer Cells

Astrocyte Elevated Gene-1: A Novel Target for Human Glioma Therapy

Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner

Sorafenib and Vorinostat Kill Colon Cancer Cells by CD95-Dependent and -Independent Mechanisms

mda- 7/IL-24: A unique member of the IL-10 gene family promoting cancer-targeted toxicity

Poly(ADP-ribose) polymerase 1 modulates the lethality of CHK1 inhibitors in carcinoma cells

Vorinostat and Sorafenib Synergistically Kill Tumor Cells via FLIP Suppression and CD95 Activation

Inhibition of MCL-1 in breast cancer cells promotes cell death in vitro and in vivo

Inhibition of vimentin or β1 integrin reverts morphology of prostate tumor cells grown in laminin-rich extracellular matrix gels and reduces tumor growth in vivo

OSU-03012 suppresses GRP78/BiP expression that causes PERK-dependent increases in tumor cell killing

Sorafenib and HDAC inhibitors synergize to kill CNS tumor cells

Ionizing Radiation Causes a Dose-Dependent Release of Transforming Growth Factor α In vitro from Irradiated Xenografts and during Palliative Treatment of Hormone-Refractory Prostate Carcinoma

Lapatinib Resistance in HCT116 Cells Is Mediated by Elevated MCL-1 Expression and Decreased BAK Activation and Not by ERBB Receptor Kinase Mutation

OSU-03012 Stimulates PKR-Like Endoplasmic Reticulum-Dependent Increases in 70-kDa Heat Shock Protein Expression, Attenuating Its Lethal Actions in Transformed Cells

OSU-03012 Promotes Caspase-Independent but PERK-, Cathepsin B-, BID-, and AIF-Dependent Killing of Transformed Cells

RLIP76 in Defense of Radiation Poisoning

PERK-dependent regulation of MDA-7/IL-24-induced autophagy in primary human glioma cells

Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes

RLIP76 is a major determinant of radiation sensitivity

MDA-7/IL-24 as a cancer therapeutic: from bench to bedside

Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways

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