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Identifying therapeutic drug targets using bidirectional effect genes

Nature communications, 2021-04, Vol.12 (1), p.2224-2224, Article 2224

2021

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Translation Initiation Factor eIF3b Expression in Human Cancer and Its Role in Tumor Growth and Lung Colonization

Clinical cancer research, 2013-06, Vol.19 (11), p.2850-2860

2013

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CD44 and RHAMM are essential for rapid growth of bladder cancer driven by loss of Glycogen Debranching Enzyme (AGL)

BMC cancer, 2016-09, Vol.16 (1), p.713-713, Article 713

2016

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Dynamic variations in epithelial-to-mesenchymal transition (EMT), ATM, and SLFN11 govern response to PARP inhibitors and cisplatin in small cell lung cancer

Oncotarget, 2017-04, Vol.8 (17), p.28575-28587

2017

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Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas

JAMA oncology, 2017-12, Vol.3 (12), p.1654

2017

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Loss of Glycogen Debranching Enzyme AGL Drives Bladder Tumor Growth via Induction of Hyaluronic Acid Synthesis

Clinical cancer research, 2016-03, Vol.22 (5), p.1274-1283

2016

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A 20-gene model for molecular nodal staging of bladder cancer: development and prospective assessment

The lancet oncology, 2011-02, Vol.12 (2), p.137-143

2011

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Role in Tumor Growth of a Glycogen Debranching Enzyme Lost in Glycogen Storage Disease

JNCI : Journal of the National Cancer Institute, 2014-04, Vol.106 (5), p.1

2014

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Induction of ER Stress by an AAV5 BDD FVIII Construct Is Dependent on the Strength of the Hepatic-Specific Promoter

Molecular therapy. Methods & clinical development, 2020-09, Vol.18, p.620-630

2020

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A Framework to Select Clinically Relevant Cancer Cell Lines for Investigation by Establishing Their Molecular Similarity with Primary Human Cancers

Cancer research (Chicago, Ill.), 2011-12, Vol.71 (24), p.7398-7409

2011

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Contributions of KRAS and RAL in Non–Small-Cell Lung Cancer Growth and Progression

Journal of thoracic oncology, 2013-12, Vol.8 (12), p.1492-1501

2013

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Biomarkers for prognosis and treatment selection in advanced bladder cancer patients

Current opinion in urology, 2011-09, Vol.21 (5), p.420-427

2011

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Abstract 3756: PARP inhibitor sensitivity in small cell lung cancer cell lines and patient-derived xenografts correlates with SLFN11 expression but not with structural homologous recombination deficiency

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.3756-3756

2016

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Neurofilament light is a treatment‐responsive biomarker in CLN2 disease

Annals of clinical and translational neurology, 2019-12, Vol.6 (12), p.2437-2447

2019

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The multiMiR R package and database: integration of microRNA-target interactions along with their disease and drug associations

Nucleic acids research, 2014-09, Vol.42 (17), p.e133

2014

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Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition

Oncotarget, 2016-11, Vol.7 (47), p.76534-76550

2016

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Utilizing TCR-Seq to Detect Tabelecleucel, an Allogeneic Epstein-Barr Virus (EBV)-Specific T-Cell Immunotherapy, Post-Infusion

Blood, 2022-11, Vol.140 (Supplement 1), p.4966-4967

2022

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Abstract 4949: HAS2 is a critical effector for AGL mediated regulation of tumor growth

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.4949-4949

2015

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Abstract P6-08-24: Age independently predicts worse disease-specific survival in patients diagnosed with invasive breast cancers at 50 years of age or older but not younger

Cancer research (Chicago, Ill.), 2015-05, Vol.75 (9_Supplement), p.P6-P6-08-24

2015

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SplicingTypesAnno: Annotating and quantifying alternative splicing events for RNA-Seq data

Computer methods and programs in biomedicine, 2015-04, Vol.119 (1), p.53-62

2015

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202 - Utilizing TCR-Seq to Detect Tabelecleucel (Tab-cel), an Allogeneic Epstein–Barr Virus (EBV)-Specific T-Cell Immunotherapy, Post-Infusion

Transplantation and cellular therapy, 2023-02, Vol.29 (2), p.S158-S158

2023

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Utilizing TCR-Seq to Detect Tabelecleucel (Tab-cel), an Allogeneic Epstein–Barr Virus (EBV)-Specific T-Cell Immunotherapy, Post-Infusion

Transplantation and cellular therapy, 2023-02, Vol.29 (2), p.S158

2023

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Abstract A37: Talazoparib predictive biomarker analysis in human small cell lung cancer cells and PDX tumors

Molecular cancer therapeutics, 2015-12, Vol.14 (12_Supplement_2), p.A37-A37

2015

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Abstract 2899: Significance of microRNA:target interaction in bladder cancer metastasis

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.2899-2899

2013

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Abstract 4604: PTP4A3 is oncogenic and modulates triple negative breast cancer growth

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.4604-4604

2014

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Identifying therapeutic drug targets using bidirectional effect genes

Translation Initiation Factor eIF3b Expression in Human Cancer and Its Role in Tumor Growth and Lung Colonization

CD44 and RHAMM are essential for rapid growth of bladder cancer driven by loss of Glycogen Debranching Enzyme (AGL)

Dynamic variations in epithelial-to-mesenchymal transition (EMT), ATM, and SLFN11 govern response to PARP inhibitors and cisplatin in small cell lung cancer

Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas

Loss of Glycogen Debranching Enzyme AGL Drives Bladder Tumor Growth via Induction of Hyaluronic Acid Synthesis

A 20-gene model for molecular nodal staging of bladder cancer: development and prospective assessment

Role in Tumor Growth of a Glycogen Debranching Enzyme Lost in Glycogen Storage Disease

Induction of ER Stress by an AAV5 BDD FVIII Construct Is Dependent on the Strength of the Hepatic-Specific Promoter

A Framework to Select Clinically Relevant Cancer Cell Lines for Investigation by Establishing Their Molecular Similarity with Primary Human Cancers

Contributions of KRAS and RAL in Non–Small-Cell Lung Cancer Growth and Progression

Biomarkers for prognosis and treatment selection in advanced bladder cancer patients

Abstract 3756: PARP inhibitor sensitivity in small cell lung cancer cell lines and patient-derived xenografts correlates with SLFN11 expression but not with structural homologous recombination deficiency

Neurofilament light is a treatment‐responsive biomarker in CLN2 disease

The multiMiR R package and database: integration of microRNA-target interactions along with their disease and drug associations

Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition

Utilizing TCR-Seq to Detect Tabelecleucel, an Allogeneic Epstein-Barr Virus (EBV)-Specific T-Cell Immunotherapy, Post-Infusion

Abstract 4949: HAS2 is a critical effector for AGL mediated regulation of tumor growth

Abstract P6-08-24: Age independently predicts worse disease-specific survival in patients diagnosed with invasive breast cancers at 50 years of age or older but not younger

SplicingTypesAnno: Annotating and quantifying alternative splicing events for RNA-Seq data

202 - Utilizing TCR-Seq to Detect Tabelecleucel (Tab-cel), an Allogeneic Epstein–Barr Virus (EBV)-Specific T-Cell Immunotherapy, Post-Infusion

Utilizing TCR-Seq to Detect Tabelecleucel (Tab-cel), an Allogeneic Epstein–Barr Virus (EBV)-Specific T-Cell Immunotherapy, Post-Infusion

Abstract A37: Talazoparib predictive biomarker analysis in human small cell lung cancer cells and PDX tumors

Abstract 2899: Significance of microRNA:target interaction in bladder cancer metastasis

Abstract 4604: PTP4A3 is oncogenic and modulates triple negative breast cancer growth

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