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Selective in vivo metabolic cell-labeling-mediated cancer targeting

Nature chemical biology, 2017-04, Vol.13 (4), p.415

2017

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Editing human hematopoietic stem cells: advances and challenges

Cytotherapy (Oxford, England), 2023-03, Vol.25 (3), p.261-269

2023

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Generation of induced pluripotent stem cells in the absence of drug selection

Cell stem cell, 2007-09, Vol.1 (3), p.245-247

2007

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Potent and uniform fetal hemoglobin induction via base editing

Nature genetics, 2023-07, Vol.55 (7), p.1210-1220

2023

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Butyrate Greatly Enhances Derivation of Human Induced Pluripotent Stem Cells by Promoting Epigenetic Remodeling and the Expression of Pluripotency‐Associated Genes

Stem cells (Dayton, Ohio), 2010-04, Vol.28 (4), p.713-720

2010

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Bone-marrow-homing lipid nanoparticles for genome editing in diseased and malignant haematopoietic stem cells

Nature nanotechnology, 2024-05

2024

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TRIAMF: A New Method for Delivery of Cas9 Ribonucleoprotein Complex to Human Hematopoietic Stem Cells

Scientific reports, 2018-11, Vol.8 (1), p.16304-11, Article 16304

2018

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Limitations of mouse models for sickle cell disease conferred by their human globin transgene configurations

Disease models & mechanisms, 2022-06, Vol.15 (6)

2022

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Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice

Nature biomedical engineering, 2023-05, Vol.7 (5), p.616

2023

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Base Editing Eliminates the Sickle Cell Mutation and Pathology in Hematopoietic Stem Cells Derived Erythroid Cells

Blood, 2020-11, Vol.136 (Supplement 1), p.13-14

2020

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Bioorthogonal Oxime Ligation Mediated In Vivo Cancer Targeting

Chemical science (Cambridge), 2015-04, Vol.6 (4), p.2182-2186

2015

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An RPS19-edited model for Diamond-Blackfan anemia reveals TP53-dependent impairment of hematopoietic stem cell activity

JCI insight, 2023-01, Vol.8 (1)

2023

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DEVELOPMENT OF NEW GENE EDITING APPROACHES FOR BONE MARROW FAILURE AND MDS PREDISPOSITION SYNDROMES

EJC paediatric oncology, 2023-12, Vol.2, p.100063, Article 100063

2023

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Efficient derivation and genetic modifications of human pluripotent stem cells on engineered human feeder cell lines

Stem cells and development, 2012-08, Vol.21 (12), p.2298

2012

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Cationic, helical polypeptide-based gene delivery for IMR-90 fibroblasts and human embryonic stem cells

Biomaterials science, 2013-01, Vol.1 (7), p.719-727

2013

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Cancer pain: Magdi Hanna, Zbigniew (Ben) Zylicz (editors). Springer-Verlag London, 2013, 286 pages, ebook version available. ISBN 978-0-85729-229-2

Canadian journal of anesthesia, 2014-05, Vol.61 (5), p.504-505

Yen, Jonathan

2014

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Directed evolution of adenine base editors with increased activity and therapeutic application

Nature biotechnology, 2020-07, Vol.38 (7), p.892-900

2020

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Gene Therapy and Gene Editing for β-Thalassemia

Hematology/oncology clinics of North America, 2023-04, Vol.37 (2), p.433-447

2023

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Non-invasive, real-time reporting drug release in vitro and in vivo

Chemical communications (Cambridge, England), 2015-04, Vol.51 (32), p.6948-6951

2015

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A Novel RPS19-Edited Hematopoietic Stem Cell Model of Diamond-Blackfan Anemia for Development of Lentiviral Vector Gene Therapy

Blood, 2021-11, Vol.138 (Supplement 1), p.859-859

2021

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Base Editing for Therapeutic Induction of Fetal Hemoglobin in β-Thalassemia

Blood, 2022-11, Vol.140 (Supplement 1), p.10660-10661

2022

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Increased Potency and Uniformity of Fetal Hemoglobin Induction from Base Editing Compared to Cas9 Nuclease

Blood, 2022-11, Vol.140 (Supplement 1), p.7784-7785

2022

Volltextzugriff (PDF)

Enhanced Non-Viral Gene Delivery to Human Embryonic Stem Cells via Small Molecule-Mediated Transient Alteration of Cell Structure

Journal of materials chemistry. B, Materials for biology and medicine, 2014-01, Vol.2 (46), p.8098-8105

2014

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