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Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme

Science (American Association for the Advancement of Science), 2010-11, Vol.330 (6005), p.831-835

2010

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Small-molecule activators of insulin-degrading enzyme discovered through high-throughput compound screening

PloS one, 2009-04, Vol.4 (4), p.e5274-e5274

2009

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Inhibitors of RecA Activity Discovered by High-Throughput Screening: Cell-Permeable Small Molecules Attenuate the SOS Response in Escherichia coli

Journal of biomolecular screening, 2009-10, Vol.14 (9), p.1092-1101

2009

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Old Drug New Use―Amoxapine and Its Metabolites as Potent Bacterial β-Glucuronidase Inhibitors for Alleviating Cancer Drug Toxicity

Clinical cancer research, 2014-07, Vol.20 (13), p.3521-3530

2014

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Development of a mechanism-based assay for tissue transglutaminase—results of a high-throughput screen and discovery of inhibitors

Analytical biochemistry, 2005-03, Vol.338 (2), p.237-244

2005

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Potential repurposing of known drugs as potent bacterial β-glucuronidase inhibitors

Journal of biomolecular screening, 2012-08, Vol.17 (7), p.957-965

2012

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Utilization of a copper-catalyzed diaryl ether synthesis for the preparation of verbenachalcone

Tetrahedron, 2002-09, Vol.58 (39), p.7903-7910

2002

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Two approaches to drug discovery in SOD1-mediated ALS

Journal of biomolecular screening, 2006-10, Vol.11 (7), p.729-735

2006

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Chemical Composition and Fatty Acid Content of Some Spices and Herbs under Saudi Arabia Conditions

TheScientificWorld, 2012-01, Vol.2012 (2012), p.1-5

2012

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Interaction of Herbal Compounds with Biological Targets : A Case Study with Berberine

TheScientificWorld, 2012-01, Vol.2012 (2012), p.1-31

2012

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Recombinant human sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDHS) is expressed at high yield as an active homotetramer in baculovirus-infected insect cells

Protein expression and purification, 2011-01, Vol.75 (1), p.104-113

2011

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Synthesis, stereochemistry confirmation and biological activity evaluation of a constituent from Isodon excisus

Tetrahedron, 2003-12, Vol.59 (50), p.9961-9969

2003

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Identifying druglike inhibitors of myelin-reactive T cells by phenotypic high-throughput screening of a small-molecule library

Journal of biomolecular screening, 2007-06, Vol.12 (4), p.481-489

2007

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Homogeneous time-resolved fluorescence resonance energy transfer assay for measurement of Phox/Bem1p (PB1) domain heterodimerization

Journal of biomolecular screening, 2008-06, Vol.13 (5), p.396-405

2008

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A High-Throughput Screen to Identify Inhibitors of Amyloid β-Protein Precursor Processing

Journal of biomolecular screening, 2005-02, Vol.10 (1), p.1-12

2005

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Indoxyl Sulfate-Induced Oxidative Stress, Mitochondrial Dysfunction, and Impaired Biogenesis Are Partly Protected by Vitamin C and N-Acetylcysteine

TheScientificWorld, 2015, Vol.2015 (2015), p.1-6

2015

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The Antiproliferative and Apoptotic Effects of Sirtinol, a Sirtuin Inhibitor on Human Lung Cancer Cells by Modulating Akt/β-Catenin-Foxo3A Axis

TheScientificWorld, 2014-01, Vol.2014 (2014), p.1-8

2014

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Effects of a verbenachalcone derivative on neurite outgrowth, inhibition of caspase induction and gene expression

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (4), p.1193-1196

2005

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Structure-based development of a novel collagen inhibitor for MMP-1: re-designing the functions of a matrix protein

Frontiers in bioscience, 2004-09, Vol.9 (1-3), p.2788

2004

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A Chinese Herbal Medicine, Jia-Wei-Xiao-Yao-San, Prevents Dimethylnitrosamine-Induced Hepatic Fibrosis in Rats

TheScientificWorld, 2014-01, Vol.2014 (2014), p.1-7

2014

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Survival Analysis by Penalized Regression and Matrix Factorization

TheScientificWorld, 2013-01, Vol.2013 (2013), p.1-11

2013

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Hydrogen Sulfide Increases Nitric Oxide Production and Subsequent S-Nitrosylation in Endothelial Cells

TheScientificWorld, 2014-01, Vol.2014 (2014), p.1-8

2014

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Evaluation of Cinnamomum osmophloeum Kanehira Extracts on Tyrosinase Suppressor, Wound Repair Promoter, and Antioxidant

TheScientificWorld, 2015, Vol.2015 (2015), p.1-7

2015

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Development of an assay to screen for inhibitors of tau phosphorylation by cdk5

Journal of biomolecular screening, 2004-03, Vol.9 (2), p.122-131

2004

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Discovery of compounds that will prevent tau pathology

Journal of molecular neuroscience, 2002-12, Vol.19 (3), p.261-266

2002

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Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme

Small-molecule activators of insulin-degrading enzyme discovered through high-throughput compound screening

Inhibitors of RecA Activity Discovered by High-Throughput Screening: Cell-Permeable Small Molecules Attenuate the SOS Response in Escherichia coli

Old Drug New Use―Amoxapine and Its Metabolites as Potent Bacterial β-Glucuronidase Inhibitors for Alleviating Cancer Drug Toxicity

Development of a mechanism-based assay for tissue transglutaminase—results of a high-throughput screen and discovery of inhibitors

Potential repurposing of known drugs as potent bacterial β-glucuronidase inhibitors

Utilization of a copper-catalyzed diaryl ether synthesis for the preparation of verbenachalcone

Two approaches to drug discovery in SOD1-mediated ALS

Chemical Composition and Fatty Acid Content of Some Spices and Herbs under Saudi Arabia Conditions

Interaction of Herbal Compounds with Biological Targets : A Case Study with Berberine

Recombinant human sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDHS) is expressed at high yield as an active homotetramer in baculovirus-infected insect cells

Synthesis, stereochemistry confirmation and biological activity evaluation of a constituent from Isodon excisus

Identifying druglike inhibitors of myelin-reactive T cells by phenotypic high-throughput screening of a small-molecule library

Homogeneous time-resolved fluorescence resonance energy transfer assay for measurement of Phox/Bem1p (PB1) domain heterodimerization

A High-Throughput Screen to Identify Inhibitors of Amyloid β-Protein Precursor Processing

Indoxyl Sulfate-Induced Oxidative Stress, Mitochondrial Dysfunction, and Impaired Biogenesis Are Partly Protected by Vitamin C and N-Acetylcysteine

The Antiproliferative and Apoptotic Effects of Sirtinol, a Sirtuin Inhibitor on Human Lung Cancer Cells by Modulating Akt/β-Catenin-Foxo3A Axis

Effects of a verbenachalcone derivative on neurite outgrowth, inhibition of caspase induction and gene expression

Structure-based development of a novel collagen inhibitor for MMP-1: re-designing the functions of a matrix protein

A Chinese Herbal Medicine, Jia-Wei-Xiao-Yao-San, Prevents Dimethylnitrosamine-Induced Hepatic Fibrosis in Rats

Survival Analysis by Penalized Regression and Matrix Factorization

Hydrogen Sulfide Increases Nitric Oxide Production and Subsequent S-Nitrosylation in Endothelial Cells

Evaluation of Cinnamomum osmophloeum Kanehira Extracts on Tyrosinase Suppressor, Wound Repair Promoter, and Antioxidant

Development of an assay to screen for inhibitors of tau phosphorylation by cdk5

Discovery of compounds that will prevent tau pathology

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