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Genomic and virulence analysis of in vitro cultured Cryptosporidium parvum

PLoS pathogens, 2024-02, Vol.20 (2), p.e1011992-e1011992

2024

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Mitochondrial Glycolysis in a Major Lineage of Eukaryotes

Genome biology and evolution, 2018-09, Vol.10 (9), p.2310-2325

2018

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SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis

PLoS neglected tropical diseases, 2011-06, Vol.5 (6), p.e1151

2011

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Long-term in vitro Culture of Cryptosporidium parvum

Bio-protocol, 2018-08, Vol.8 (15), p.e2947-e2947

2018

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Discovery of Novel Orally Bioavailable Oxaborole 6-Carboxamides That Demonstrate Cure in a Murine Model of Late-Stage Central Nervous System African Trypanosomiasis

Antimicrobial Agents and Chemotherapy, 2010-10, Vol.54 (10), p.4379-4388

2010

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Novel Synthetic Polyamines Have Potent Antimalarial Activities in vitro and in vivo by Decreasing Intracellular Spermidine and Spermine Concentrations

Frontiers in cellular and infection microbiology, 2019-02, Vol.9, p.9-9

2019

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Pharmacokinetics and pharmacodynamics utilizing unbound target tissue exposure as part of a disposition-based rationale for lead optimization of benzoxaboroles in the treatment of Stage 2 Human African Trypanosomiasis

Parasitology, 2014-01, Vol.141 (1), p.104-118

2014

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2,4-Diaminopyrimidines as potent inhibitors of Trypanosoma brucei and identification of molecular targets by a chemical proteomics approach

PLoS neglected tropical diseases, 2011-02, Vol.5 (2), p.e956

2011

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Biochemical characterization of a mitochondrial-like organelle from Blastocystis sp. subtype 7

Microbiology (Society for General Microbiology), 2008-09, Vol.154 (Pt 9), p.2757-2766

2008

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Abstract 1771 Quantifying the Efficacy of Suspected Cryptosporidium parvum Malate Dehydrogenase Inhibitors

The Journal of biological chemistry, 2024-03, Vol.300 (3), p.106101, Article 106101

2024

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Trypanocidal Activity of 8-Methyl-5′-{[(Z)-4-Aminobut-2-enyl]-(Methylamino)}Adenosine (Genz-644131), an Adenosylmethionine Decarboxylase Inhibitor

Antimicrobial Agents and Chemotherapy, 2009-08, Vol.53 (8), p.3269-3272

2009

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Novel S-Adenosylmethionine Decarboxylase Inhibitors for the Treatment of Human African Trypanosomiasis

Antimicrobial Agents and Chemotherapy, 2009-05, Vol.53 (5), p.2052-2058

2009

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Alkanediamide-Linked Bisbenzamidines Are Promising Antiparasitic Agents

Pharmaceuticals (Basel, Switzerland), 2016-04, Vol.9 (2), p.20

2016

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Hydrogenosome-localization of arginine deiminase in Trichomonas vaginalis

Molecular and biochemical parasitology, 2011-03, Vol.176 (1), p.51-54

2011

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Continuous culture of Cryptosporidium parvum using hollow fiber technology

International journal for parasitology, 2016-01, Vol.46 (1), p.21-29

2016

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Protists: Eukaryotic single-celled organisms and the functioning of their organelles

Advances in microbial physiology, 2024, Vol.84, p.243

2024

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Metabolism of an Alkyl Polyamine Analog by a Polyamine Oxidase from the Microsporidian Encephalitozoon cuniculi

Antimicrobial Agents and Chemotherapy, 2009-06, Vol.53 (6), p.2599-2604

2009

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Inducible Resistance to Oxidant Stress in the Protozoan Leishmania chagasi

The Journal of biological chemistry, 2000-10, Vol.275 (43), p.33883-33889

2000

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Cryptosporidium parvum Induces an Endoplasmic Stress Response in the Intestinal Adenocarcinoma HCT-8 Cell Line

The Journal of biological chemistry, 2013-10, Vol.288 (42), p.30356-30364

2013

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Novel Synthetic Polyamines Are Effective in the Treatment of Experimental Microsporidiosis, an Opportunistic AIDS-Associated Infection

Antimicrobial Agents and Chemotherapy, 2002-01, Vol.46 (1), p.55-61

2002

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In Memoriam: Edward Jarroll (1948–2017)

The Journal of eukaryotic microbiology, 2018-05, Vol.65 (3), p.432-433

2018

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Activities of DL-α-Difluoromethylarginine and Polyamine Analogues against Cryptosporidium parvum Infection in a T-Cell Receptor Alpha-Deficient Mouse Model

Antimicrobial Agents and Chemotherapy, 2007-04, Vol.51 (4), p.1234-1239

2007

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Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides

Bioorganic & medicinal chemistry letters, 2018-01, Vol.28 (2), p.207-213

2018

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P-Glycoprotein–Mediated Efflux Reduces the In Vivo Efficacy of a Therapeutic Targeting the Gastrointestinal Parasite Cryptosporidium

The Journal of infectious diseases, 2019-08, Vol.220 (7), p.1188-1198

2019

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In Memoriam: Michael Levandowsky (1935–2016)

The Journal of eukaryotic microbiology, 2017-07, Vol.64 (4), p.558-559

2017

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Genomic and virulence analysis of in vitro cultured Cryptosporidium parvum

Mitochondrial Glycolysis in a Major Lineage of Eukaryotes

SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis

Long-term in vitro Culture of Cryptosporidium parvum

Discovery of Novel Orally Bioavailable Oxaborole 6-Carboxamides That Demonstrate Cure in a Murine Model of Late-Stage Central Nervous System African Trypanosomiasis

Novel Synthetic Polyamines Have Potent Antimalarial Activities in vitro and in vivo by Decreasing Intracellular Spermidine and Spermine Concentrations

Pharmacokinetics and pharmacodynamics utilizing unbound target tissue exposure as part of a disposition-based rationale for lead optimization of benzoxaboroles in the treatment of Stage 2 Human African Trypanosomiasis

2,4-Diaminopyrimidines as potent inhibitors of Trypanosoma brucei and identification of molecular targets by a chemical proteomics approach

Biochemical characterization of a mitochondrial-like organelle from Blastocystis sp. subtype 7

Abstract 1771 Quantifying the Efficacy of Suspected Cryptosporidium parvum Malate Dehydrogenase Inhibitors

Trypanocidal Activity of 8-Methyl-5′-{[(Z)-4-Aminobut-2-enyl]-(Methylamino)}Adenosine (Genz-644131), an Adenosylmethionine Decarboxylase Inhibitor

Novel S-Adenosylmethionine Decarboxylase Inhibitors for the Treatment of Human African Trypanosomiasis

Alkanediamide-Linked Bisbenzamidines Are Promising Antiparasitic Agents

Hydrogenosome-localization of arginine deiminase in Trichomonas vaginalis

Continuous culture of Cryptosporidium parvum using hollow fiber technology

Protists: Eukaryotic single-celled organisms and the functioning of their organelles

Metabolism of an Alkyl Polyamine Analog by a Polyamine Oxidase from the Microsporidian Encephalitozoon cuniculi

Inducible Resistance to Oxidant Stress in the Protozoan Leishmania chagasi

Cryptosporidium parvum Induces an Endoplasmic Stress Response in the Intestinal Adenocarcinoma HCT-8 Cell Line

Novel Synthetic Polyamines Are Effective in the Treatment of Experimental Microsporidiosis, an Opportunistic AIDS-Associated Infection

In Memoriam: Edward Jarroll (1948–2017)

Activities of DL-α-Difluoromethylarginine and Polyamine Analogues against Cryptosporidium parvum Infection in a T-Cell Receptor Alpha-Deficient Mouse Model

Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides

P-Glycoprotein–Mediated Efflux Reduces the In Vivo Efficacy of a Therapeutic Targeting the Gastrointestinal Parasite Cryptosporidium

In Memoriam: Michael Levandowsky (1935–2016)

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