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Biological profiles of highly potent novel endothelin antagonists selective for the ETA receptor

Life sciences (1973), 1992, Vol.50 (4), p.247-255

1992

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An endothelin receptor (ET A) antagonist isolated from Streptomyces misakiensis

Biochemical and biophysical research communications, 1991-07, Vol.178 (1), p.132-137

1991

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Synergistic inhibition by BQ‐123 and BQ‐788 of endothelin‐1‐induced contractions of the rabbit pulmonary artery

British journal of pharmacology, 1994-10, Vol.113 (2), p.336-338

1994

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Necessity of dual blockade of endothelin ETA and ETB receptor subtypes for antagonism of endothelin‐1‐induced contraction in human bronchi

British journal of pharmacology, 1996-03, Vol.117 (6), p.995-999

1996

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Different distribution of endothelin receptor subtypes in pulmonary tissues revealed by the novel selective ligands BQ-123 and [Ala 1,3,11,15]ET-1

Biochemical and biophysical research communications, 1992-01, Vol.182 (1), p.144-150

1992

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Protective effect of a selective endothelin receptor antagonist, BQ-123, in ischemic acute renal failure in rats

European journal of pharmacology, 1992-10, Vol.221 (1), p.77-83

1992

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Increased expression of endothelin B receptor mRNA following subarachnoid hemorrhage in monkeys

Journal of cerebral blood flow and metabolism, 1996-07, Vol.16 (4), p.688-697

1996

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Inhibition of biological actions of big endothelin-1 by phosphoramidon

Biochemical and biophysical research communications, 1990-10, Vol.172 (2), p.390-395

1990

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Antihypertensive effect of a newly synthesized endothelin antagonist, BQ-123, in a genetic hypertensive model

Life sciences (1973), 1993, Vol.52 (8), p.717-724

1993

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A novel ETA antagonist (BQ‐123) inhibits endothelin‐1‐induced phosphoinositide breakdown and DNA synthesis in rat vascular smooth muscle cells

FEBS letters, 1992-05, Vol.302 (3), p.243-246

1992

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The role of endothelin and nitric oxide in modulation of normal and spastic cerebral vascular tone in the dog

European journal of pharmacology, 1995-04, Vol.277 (1), p.77-87

1995

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Block of Endothelin‐1‐induced release of thromboxane A2 from the guinea pig lung and nitric oxide from the rabbit kidney by a selective ETB receptor antagonist, BQ‐788

British journal of pharmacology, 1994-12, Vol.113 (4), p.1257-1262

1994

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Synthesis and Structure−Activity Relationships of 2-Substituted d-Tryptophan-Containing Peptidic Endothelin Receptor Antagonists: Importance of the C-2 Substituent of the d-Tryptophan Residue for Endothelin A and B Receptor Subtype Selectivity

Journal of medicinal chemistry, 1996-06, Vol.39 (12), p.2313-2330

1996

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Clearance of circulating endothelin-1 by ETB receptors in rats

Biochemical and biophysical research communications, 1994-03, Vol.199 (3), p.1461-1465

1994

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[3H]BQ-123, a highly specific and reversible radioligand for the endothelin ETA receptor subtype

European journal of pharmacology, 1995-02, Vol.274 (1-3), p.1-6

1995

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Biochemical and Pharmacological Profile of a Potent and Selective Endothelin B-Receptor Antagonist, BQ-788

Proceedings of the National Academy of Sciences - PNAS, 1994-05, Vol.91 (11), p.4892-4896

1994

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Contribution of Endogenous Endothelin-1 to the Progression of Cardiopulmonary Alterations in Rats With Monocrotaline-Induced Pulmonary Hypertension

Circulation research, 1993-11, Vol.73 (5), p.887-897

1993

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Evidence for atypical endothelin receptors and for presence of endothelin-converting enzyme activity in the mouse isolated vas deferens

European journal of pharmacology, 1995-03, Vol.276 (1), p.113-121

1995

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Coexpression Studies with Endothelin Receptor Subtypes Indicate the Existence of Intracellular Cross-Talk between ETA and ETB Receptors

Journal of biochemistry (Tokyo), 1997-03, Vol.121 (3), p.440-447

1997

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Local formation and degradation of endothelin-1 in guinea pig airway tissues

Biochemical and biophysical research communications, 1991-09, Vol.179 (2), p.830-835

1991

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Avaliação do consumo alimentar, uso de suplementos e o conhecimento acerca da alimentação adequada por praticantes de atividade física de uma academia em Joinville-SC

Revista brasileira de nutrição esportiva, 2021-07, Vol.15 (91), p.128-140

2021

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[Ala1,3,11,15]endothelin-1 analogs with ETB agonistic activity

Biochemical and biophysical research communications, 1991-08, Vol.179 (1), p.286-292

1991

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CORONARY VASCULAR RESPONSE TO ENDOTHELIN IN ISOLATED PERFUSED HEARTS OF SPONTANEOUSLY HYPERTENSIVE RATS

Clinical and experimental pharmacology & physiology, 1991-09, Vol.18 (9), p.661-669

1991

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ENDOTHELIN-BINDING INHIBITORS, BE-18257A AND BE-18257B: I. TAXONOMY, FERMENTATION, ISOLATION AND CHARACTERIZATION

The Journal of Antibiotics, 1991/12/25, Vol.44(12), pp.1342-1347

1991

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Synthesis of Human Big Endothelin-1 by Sequence-Specific Proteolysis of a Fusion Protein in Escherichia coli

Journal of biochemistry (Tokyo), 1991-10, Vol.110 (4), p.628-634

1991

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Biological profiles of highly potent novel endothelin antagonists selective for the ETA receptor

An endothelin receptor (ET A) antagonist isolated from Streptomyces misakiensis

Synergistic inhibition by BQ‐123 and BQ‐788 of endothelin‐1‐induced contractions of the rabbit pulmonary artery

Necessity of dual blockade of endothelin ETA and ETB receptor subtypes for antagonism of endothelin‐1‐induced contraction in human bronchi

Different distribution of endothelin receptor subtypes in pulmonary tissues revealed by the novel selective ligands BQ-123 and [Ala 1,3,11,15]ET-1

Protective effect of a selective endothelin receptor antagonist, BQ-123, in ischemic acute renal failure in rats

Increased expression of endothelin B receptor mRNA following subarachnoid hemorrhage in monkeys

Inhibition of biological actions of big endothelin-1 by phosphoramidon

Antihypertensive effect of a newly synthesized endothelin antagonist, BQ-123, in a genetic hypertensive model

A novel ETA antagonist (BQ‐123) inhibits endothelin‐1‐induced phosphoinositide breakdown and DNA synthesis in rat vascular smooth muscle cells

The role of endothelin and nitric oxide in modulation of normal and spastic cerebral vascular tone in the dog

Block of Endothelin‐1‐induced release of thromboxane A2 from the guinea pig lung and nitric oxide from the rabbit kidney by a selective ETB receptor antagonist, BQ‐788

Synthesis and Structure−Activity Relationships of 2-Substituted d-Tryptophan-Containing Peptidic Endothelin Receptor Antagonists: Importance of the C-2 Substituent of the d-Tryptophan Residue for Endothelin A and B Receptor Subtype Selectivity

Clearance of circulating endothelin-1 by ETB receptors in rats

[3H]BQ-123, a highly specific and reversible radioligand for the endothelin ETA receptor subtype

Biochemical and Pharmacological Profile of a Potent and Selective Endothelin B-Receptor Antagonist, BQ-788

Contribution of Endogenous Endothelin-1 to the Progression of Cardiopulmonary Alterations in Rats With Monocrotaline-Induced Pulmonary Hypertension

Evidence for atypical endothelin receptors and for presence of endothelin-converting enzyme activity in the mouse isolated vas deferens

Coexpression Studies with Endothelin Receptor Subtypes Indicate the Existence of Intracellular Cross-Talk between ETA and ETB Receptors

Local formation and degradation of endothelin-1 in guinea pig airway tissues

Avaliação do consumo alimentar, uso de suplementos e o conhecimento acerca da alimentação adequada por praticantes de atividade física de uma academia em Joinville-SC

[Ala1,3,11,15]endothelin-1 analogs with ETB agonistic activity

CORONARY VASCULAR RESPONSE TO ENDOTHELIN IN ISOLATED PERFUSED HEARTS OF SPONTANEOUSLY HYPERTENSIVE RATS

ENDOTHELIN-BINDING INHIBITORS, BE-18257A AND BE-18257B: I. TAXONOMY, FERMENTATION, ISOLATION AND CHARACTERIZATION

Synthesis of Human Big Endothelin-1 by Sequence-Specific Proteolysis of a Fusion Protein in Escherichia coli

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