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Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan

Angewandte Chemie International Edition, 2024-03, Vol.63 (13), p.e202316133-n/a

International ed. in English, 2024

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Preparation, mechanical and thermal properties of functionalized graphene/polyimide nanocomposites

Composites. Part A, Applied science and manufacturing, 2012-09, Vol.43 (9), p.1537-1545

2012

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Rapid Characterization of Insulin Modifications and Sequence Variations by Proteinase K Digestion and UHPLC-ESI-MS

Journal of the American Society for Mass Spectrometry, 2018-05, Vol.29 (5), p.853-858

2018

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Unexpected Propargylic Retro-Brook Rearrangements in Alkynes

Journal of organic chemistry, 2019-08, Vol.84 (16), p.10024-10031

2019

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Mechanistic Study of the Gas-Phase In-Source Hofmann Elimination of Doubly Quaternized Cinchona-Alkaloid Based Phase-Transfer Catalysts by (+)-Electrospray Ionization/Tandem Mass Spectrometry

Journal of the American Society for Mass Spectrometry, 2017-03, Vol.28 (3), p.452-460

2017

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Unusual (+/–)‐electrospray ionization induced fragmentation: Structural elucidation of an in‐process synthetic intermediate of doravirine (MK‐1439) using liquid chromatography/high‐resolution tandem mass spectrometry and two‐dimensional nuclear magnetic resonance

Rapid communications in mass spectrometry, 2017-04, Vol.31 (8), p.719-727

2017

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Advancing Structure Characterization of PS-80 by Charge-Reduced Mass Spectrometry and Software-Assisted Composition Analysis

Journal of pharmaceutical sciences, 2022-02, Vol.111 (2), p.314-322

2022

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Extensive Characterization of Polysorbate 80 Oxidative Degradation Under Stainless Steel Conditions

Journal of pharmaceutical sciences, 2023-03, Vol.112 (3), p.779-789

2023

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Low-molecular-weight impurity in Poloxamer 188 responsible for atypical cell culture performance for mAb production

Journal of biotechnology, 2022-06, Vol.351, p.13-22

2022

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A facile preparation and electrochemical properties of nickel based compound-graphene sheet composites for supercapacitors

Chinese chemical letters, 2015-05, Vol.26 (5), p.522-528

2015

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Mechanistic insight into the oxazoline decomposition of DFC-M, a synthetic intermediate of florfenicol

Journal of pharmaceutical and biomedical analysis, 2019-09, Vol.174, p.235-241

2019

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Discovery of the HCV NS3/4A Protease Inhibitor (1R,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key Steps in Structure-Based Optimization

Journal of medicinal chemistry, 2007-05, Vol.50 (10), p.2310-2318

2007

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Development of a highly efficient decontamination approach for ceftolozane in the pharmaceutical manufacturing environment

Journal of pharmaceutical and biomedical analysis, 2020-01, Vol.177, p.112846-112846, Article 112846

2020

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Preparation and Tribological Studies of Stearic Acid Self-Assembled Monolayers on Polymer-Coated Silicon Surface

Chemistry of materials, 2004-02, Vol.16 (3), p.428-434

2004

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Mechanical and tribological behaviors of PA66/PVDF blends filled with calcium sulphate whiskers

Polymer composites, 2009-09, Vol.30 (9), p.1326-1332

2009

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Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors

Biochemistry (Easton), 2009-03, Vol.48 (12), p.2661-2674

2009

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Mechanical and tribological behaviors of polyamide 66/ultra high molecular weight polyethylene blends

Polymer engineering and science, 2007-05, Vol.47 (5), p.738-744

2007

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Applications of TiCl3 as a Diagnostic Reagent for the Detection of Nitro- and N‑Oxide-Containing Compounds as Potentially Mutagenic Impurities Using Ultrahigh-Performance Liquid Chromatography Coupled with High-Resolution Mass Spectrometry

Organic process research & development, 2016-01, Vol.20 (1), p.59-64

2016

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A Tiered Approach for Characterization to Ensure Quality, Reproducibility, and Long-Term Stability of Critical Reagents in Regulated Bioanalysis to Support PK/ADA/NAb Assays for Biologics and Vaccines Programs

ACS pharmacology & translational science, 2020-12, Vol.3 (6), p.1310-1317

2020

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Friction and Wear Behavior of Polyamide 66/Poly(vinylidene fluoride) Blends

Journal of macromolecular science. Physics, 2008-07, Vol.47 (4), p.701-711

2008

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Key steps in the structure-based optimization of the hepatitis C virus NS3/4A protease inhibitor SCH503034

Journal of synchrotron radiation, 2008-05, Vol.15 (3), p.204-207

2008

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Soil nutrients spatial variability and soil fertility suitability in Qujing tobacco-planting area

Ying yong sheng tai xue bao, 2011-04, Vol.22 (4), p.950

2011

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Research on the state dependence effect of online consumer based on random utility model

Shànghăi jiāotōng dàxué xuébào, 2010-03, Vol.44 (3), p.302-305

2010

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Influence of polydopamine coating on deposition of hydroxyapaite on oxidated titanium alloy

Shànghăi jiāotōng dàxué xuébào, 2013-05, Vol.47 (5), p.795-799

2013

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Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan

Preparation, mechanical and thermal properties of functionalized graphene/polyimide nanocomposites

Rapid Characterization of Insulin Modifications and Sequence Variations by Proteinase K Digestion and UHPLC-ESI-MS

Unexpected Propargylic Retro-Brook Rearrangements in Alkynes

Mechanistic Study of the Gas-Phase In-Source Hofmann Elimination of Doubly Quaternized Cinchona-Alkaloid Based Phase-Transfer Catalysts by (+)-Electrospray Ionization/Tandem Mass Spectrometry

Unusual (+/–)‐electrospray ionization induced fragmentation: Structural elucidation of an in‐process synthetic intermediate of doravirine (MK‐1439) using liquid chromatography/high‐resolution tandem mass spectrometry and two‐dimensional nuclear magnetic resonance

Advancing Structure Characterization of PS-80 by Charge-Reduced Mass Spectrometry and Software-Assisted Composition Analysis

Extensive Characterization of Polysorbate 80 Oxidative Degradation Under Stainless Steel Conditions

Low-molecular-weight impurity in Poloxamer 188 responsible for atypical cell culture performance for mAb production

A facile preparation and electrochemical properties of nickel based compound-graphene sheet composites for supercapacitors

Mechanistic insight into the oxazoline decomposition of DFC-M, a synthetic intermediate of florfenicol

Discovery of the HCV NS3/4A Protease Inhibitor (1R,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key Steps in Structure-Based Optimization

Development of a highly efficient decontamination approach for ceftolozane in the pharmaceutical manufacturing environment

Preparation and Tribological Studies of Stearic Acid Self-Assembled Monolayers on Polymer-Coated Silicon Surface

Mechanical and tribological behaviors of PA66/PVDF blends filled with calcium sulphate whiskers

Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors

Mechanical and tribological behaviors of polyamide 66/ultra high molecular weight polyethylene blends

Applications of TiCl3 as a Diagnostic Reagent for the Detection of Nitro- and N‑Oxide-Containing Compounds as Potentially Mutagenic Impurities Using Ultrahigh-Performance Liquid Chromatography Coupled with High-Resolution Mass Spectrometry

A Tiered Approach for Characterization to Ensure Quality, Reproducibility, and Long-Term Stability of Critical Reagents in Regulated Bioanalysis to Support PK/ADA/NAb Assays for Biologics and Vaccines Programs

Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan

Friction and Wear Behavior of Polyamide 66/Poly(vinylidene fluoride) Blends

Key steps in the structure-based optimization of the hepatitis C virus NS3/4A protease inhibitor SCH503034

Soil nutrients spatial variability and soil fertility suitability in Qujing tobacco-planting area

Research on the state dependence effect of online consumer based on random utility model

Influence of polydopamine coating on deposition of hydroxyapaite on oxidated titanium alloy

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