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Different syngeneic tumors show distinctive intrinsic tumor-immunity and mechanisms of actions (MOA) of anti-PD-1 treatment

Scientific reports, 2022-02, Vol.12 (1), p.3278-3278, Article 3278

2022

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Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model

The Journal of clinical investigation, 2008-09, Vol.118 (9), p.3051-3064

2008

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Nuclear Export of Ubiquitinated Proteins Determines the Sensitivity of Colorectal Cancer to Proteasome Inhibitor

Molecular cancer therapeutics, 2017-04, Vol.16 (4), p.717-728

2017

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A living biobank of matched pairs of patient-derived xenografts and organoids for cancer pharmacology

PloS one, 2023-01, Vol.18 (1), p.e0279821-e0279821

2023

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Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 mice

Molecular neurodegeneration, 2017-05, Vol.12 (1), p.39-16, Article 39

2017

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Composition and Histone Substrates of Polycomb Repressive Group Complexes Change during Cellular Differentiation

Proceedings of the National Academy of Sciences - PNAS, 2005-02, Vol.102 (6), p.1859-1864

2005

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Loss-of-function of Nkx3.1 promotes increased oxidative damage in prostate carcinogenesis

Cancer research (Chicago, Ill.), 2005-08, Vol.65 (15), p.6773-6779

2005

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Activator Protein-1 Transcription Factors Are Associated with Progression and Recurrence of Prostate Cancer

Cancer research (Chicago, Ill.), 2008-04, Vol.68 (7), p.2132-2144

2008

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Analysis of tau post-translational modifications in rTg4510 mice, a model of tau pathology

Molecular neurodegeneration, 2015-03, Vol.10 (1), p.14-14, Article 14

2015

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Combinatorial Activities of Akt and B-Raf/Erk Signaling in a Mouse Model of Androgen-Independent Prostate Cancer

Proceedings of the National Academy of Sciences - PNAS, 2006-09, Vol.103 (39), p.14477-14482

2006

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Emergence of androgen independence at early stages of prostate cancer progression in Nkx3.1; Pten mice

Cancer research (Chicago, Ill.), 2006-08, Vol.66 (16), p.7929-7933

2006

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Prolonged exposure to reduced levels of androgen accelerates prostate cancer progression in Nkx3.1; pten mutant mice

Cancer research (Chicago, Ill.), 2007-10, Vol.67 (19), p.9089-9096

2007

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Vitamin D Inhibits the Formation of Prostatic Intraepithelial Neoplasia in Nkx3.1; Pten Mutant Mice

Clinical cancer research, 2006-10, Vol.12 (19), p.5895-5901

2006

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Diacylglycerol acyltransferase-1 (DGAT1) inhibition perturbs postprandial gut hormone release

PloS one, 2013-01, Vol.8 (1), p.e54480-e54480

2013

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BRAF activation initiates but does not maintain invasive prostate adenocarcinoma

PloS one, 2008-12, Vol.3 (12), p.e3949-e3949

2008

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12 Development of an in vitro assay to assess bispecific T cell engager using T cells from CD3e humanized mice

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A12-A12

2020

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Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation

Science (American Association for the Advancement of Science), 2016-06, Vol.352 (6293), p.1576-1580

2016

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Experimental animal modeling for immuno-oncology

Pharmacology & therapeutics (Oxford), 2017-05, Vol.173, p.34-46

2017

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Preclinical pharmacology modeling of chimeric antigen receptor T therapies

Current opinion in pharmacology, 2021-12, Vol.61, p.49-61

2021

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Abstract 1814: Generation and validation of a novel humanized TNFR2 mouse model for the evaluation of therapeutic TNFR2 antibody

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1814-1814

2021

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Abstract 1016: Transcriptomic analysis of bulk tissues of large PDX collection as a novel platform discovering new TME target/drug

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.1016-1016

2018

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Editor's Note: Activator Protein-1 Transcription Factors Are Associated with Progression and Recurrence of Prostate Cancer

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7), p.1161-1161

2023

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Abstract B209: Transcriptomic analysis of patient-derived xenografts reveals heterogeneity in human and mouse stroma/immune compartments

Molecular cancer therapeutics, 2018-01, Vol.17 (1_Supplement), p.B209-B209

2018

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Building Kras (G12D)/Trp53 null/Pdx1-cre (KPC) mouse allograft tumor model for efficacy evaluation of combinatory immunotherapie

European journal of cancer (1990), 2018-03, Vol.92, p.S6-S6

2018

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Abstract 3219: Prior vaccination is critical to PD1/PDL-1 treatment efficacy in a mouse breast cancer allograft

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.3219-3219

2016

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Different syngeneic tumors show distinctive intrinsic tumor-immunity and mechanisms of actions (MOA) of anti-PD-1 treatment

Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model

Nuclear Export of Ubiquitinated Proteins Determines the Sensitivity of Colorectal Cancer to Proteasome Inhibitor

A living biobank of matched pairs of patient-derived xenografts and organoids for cancer pharmacology

Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 mice

Composition and Histone Substrates of Polycomb Repressive Group Complexes Change during Cellular Differentiation

Loss-of-function of Nkx3.1 promotes increased oxidative damage in prostate carcinogenesis

Activator Protein-1 Transcription Factors Are Associated with Progression and Recurrence of Prostate Cancer

Analysis of tau post-translational modifications in rTg4510 mice, a model of tau pathology

Combinatorial Activities of Akt and B-Raf/Erk Signaling in a Mouse Model of Androgen-Independent Prostate Cancer

Emergence of androgen independence at early stages of prostate cancer progression in Nkx3.1; Pten mice

Prolonged exposure to reduced levels of androgen accelerates prostate cancer progression in Nkx3.1; pten mutant mice

Vitamin D Inhibits the Formation of Prostatic Intraepithelial Neoplasia in Nkx3.1; Pten Mutant Mice

Diacylglycerol acyltransferase-1 (DGAT1) inhibition perturbs postprandial gut hormone release

BRAF activation initiates but does not maintain invasive prostate adenocarcinoma

12 Development of an in vitro assay to assess bispecific T cell engager using T cells from CD3e humanized mice

Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation

Experimental animal modeling for immuno-oncology

Preclinical pharmacology modeling of chimeric antigen receptor T therapies

Abstract 1814: Generation and validation of a novel humanized TNFR2 mouse model for the evaluation of therapeutic TNFR2 antibody

Abstract 1016: Transcriptomic analysis of bulk tissues of large PDX collection as a novel platform discovering new TME target/drug

Editor's Note: Activator Protein-1 Transcription Factors Are Associated with Progression and Recurrence of Prostate Cancer

Abstract B209: Transcriptomic analysis of patient-derived xenografts reveals heterogeneity in human and mouse stroma/immune compartments

Building Kras (G12D)/Trp53 null/Pdx1-cre (KPC) mouse allograft tumor model for efficacy evaluation of combinatory immunotherapie

Abstract 3219: Prior vaccination is critical to PD1/PDL-1 treatment efficacy in a mouse breast cancer allograft

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