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Vascular Endothelial Cells and Innate Immunity

Arteriosclerosis, thrombosis, and vascular biology, 2020-06, Vol.40 (6), p.e138

2020

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ROS systems are a new integrated network for sensing homeostasis and alarming stresses in organelle metabolic processes

Redox biology, 2020-10, Vol.37, p.101696-101696, Article 101696

2020

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Activation of specific bitter taste receptors by olive oil phenolics and secoiridoids

Scientific reports, 2021-11, Vol.11 (1), p.22340-22340, Article 22340

2021

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Endothelial Immunity Trained by Coronavirus Infections, DAMP Stimulations and Regulated by Anti-Oxidant NRF2 May Contribute to Inflammations, Myelopoiesis, COVID-19 Cytokine Storms and Thromboembolism

Frontiers in immunology, 2021-06, Vol.12, p.653110-653110

2021

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GATA3, HDAC6, and BCL6 Regulate FOXP3+ Treg Plasticity and Determine Treg Conversion into Either Novel Antigen-Presenting Cell-Like Treg or Th1-Treg

Frontiers in immunology, 2018-01, Vol.9, p.45

2018

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Caspase-11 promotes high-fat diet-induced NAFLD by increasing glycolysis, OXPHOS, and pyroptosis in macrophages

Frontiers in immunology, 2023-01, Vol.14, p.1113883-1113883

2023

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ER stress mediates Angiotensin II-augmented innate immunity memory and facilitates distinct susceptibilities of thoracic from abdominal aorta to aneurysm development

Frontiers in immunology, 2023-09, Vol.14, p.1268916-1268916

2023

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Approaching Inflammation Paradoxes-Proinflammatory Cytokine Blockages Induce Inflammatory Regulators

Frontiers in immunology, 2020-10, Vol.11, p.554301

2020

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Tissue Treg Secretomes and Transcription Factors Shared With Stem Cells Contribute to a Treg Niche to Maintain Treg-Ness With 80% Innate Immune Pathways, and Functions of Immunosuppression and Tissue Repair

Frontiers in immunology, 2021-02, Vol.11, p.632239-632239

2021

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High expression of ETS2 predicts poor prognosis in acute myeloid leukemia and may guide treatment decisions

Journal of translational medicine, 2017-07, Vol.15 (1), p.159-159, Article 159

2017

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Editorial: Sex differences and cardiovascular therapeutics

Frontiers in cardiovascular medicine, 2024-05, Vol.11, p.1420293-1420293

2024

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Procaspase-1 patrolled to the nucleus of proatherogenic lipid LPC-activated human aortic endothelial cells induces ROS promoter CYP1B1 and strong inflammation

Redox biology, 2021-11, Vol.47, p.102142-102142, Article 102142

2021

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Editorial: Endothelial cells as innate immune cells

Frontiers in immunology, 2022-10, Vol.13, p.1035497-1035497

2022

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Innate immunity of vascular smooth muscle cells contributes to two-wave inflammation in atherosclerosis, twin-peak inflammation in aortic aneurysms and trans-differentiation potential into 25 cell types

Frontiers in immunology, 2024-01, Vol.14, p.1348238

2024

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End-stage renal disease is different from chronic kidney disease in upregulating ROS-modulated proinflammatory secretome in PBMCs - A novel multiple-hit model for disease progression

Redox biology, 2020-07, Vol.34, p.101460-101460, Article 101460

2020

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Aorta in Pathologies May Function as an Immune Organ by Upregulating Secretomes for Immune and Vascular Cell Activation, Differentiation and Trans-Differentiation-Early Secretomes may Serve as Drivers for Trained Immunity

Frontiers in immunology, 2022-03, Vol.13, p.858256-858256

2022

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Chronic Exposure to the Combination of Cigarette Smoke and Morphine Decreases CD4 + Regulatory T Cell Numbers by Reprogramming the Treg Cell Transcriptome

Frontiers in immunology, 2022-04, Vol.13, p.887681-887681

2022

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Early hyperlipidemia triggers metabolomic reprogramming with increased SAH, increased acetyl-CoA-cholesterol synthesis, and decreased glycolysis

Redox biology, 2023-08, Vol.64, p.102771, Article 102771

2023

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Hyperlipidemia May Synergize with Hypomethylation in Establishing Trained Immunity and Promoting Inflammation in NASH and NAFLD

Journal of immunology research, 2021, Vol.2021, p.3928323-35

2021

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Ultrasound May Suppress Tumor Growth, Inhibit Inflammation, and Establish Tolerogenesis by Remodeling Innatome via Pathways of ROS, Immune Checkpoints, Cytokines, and Trained Immunity/Tolerance

Journal of Immunology Research, 2021, Vol.2021, p.6664453-33

2021

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IL-35 promotes CD4+Foxp3+ Tregs and inhibits atherosclerosis via maintaining CCR5-amplified Treg-suppressive mechanisms

JCI insight, 2021-10, Vol.6 (19)

2021

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Canonical Secretomes, Innate Immune Caspase-1-, 4/11-Gasdermin D Non-Canonical Secretomes and Exosomes May Contribute to Maintain Treg-Ness for Treg Immunosuppression, Tissue Repair and Modulate Anti-Tumor Immunity via ROS Pathways

Frontiers in immunology, 2021-05, Vol.12, p.678201-678201

2021

Volltextzugriff (PDF)

A Novel Subset of CD95 + Pro-Inflammatory Macrophages Overcome miR155 Deficiency and May Serve as a Switch From Metabolically Healthy Obesity to Metabolically Unhealthy Obesity

Frontiers in immunology, 2021-01, Vol.11, p.619951-619951

2021

Volltextzugriff (PDF)

29 m6A-RNA Methylation (Epitranscriptomic) Regulators Are Regulated in 41 Diseases including Atherosclerosis and Tumors Potentially via ROS Regulation – 102 Transcriptomic Dataset Analyses

Journal of immunology research, 2022-01, Vol.2022, p.1-42

2022

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High expression of CPNE3 predicts adverse prognosis in acute myeloid leukemia

Cancer science, 2017-09, Vol.108 (9), p.1850-1857

2017

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Vascular Endothelial Cells and Innate Immunity

ROS systems are a new integrated network for sensing homeostasis and alarming stresses in organelle metabolic processes

Activation of specific bitter taste receptors by olive oil phenolics and secoiridoids

Endothelial Immunity Trained by Coronavirus Infections, DAMP Stimulations and Regulated by Anti-Oxidant NRF2 May Contribute to Inflammations, Myelopoiesis, COVID-19 Cytokine Storms and Thromboembolism

GATA3, HDAC6, and BCL6 Regulate FOXP3+ Treg Plasticity and Determine Treg Conversion into Either Novel Antigen-Presenting Cell-Like Treg or Th1-Treg

Caspase-11 promotes high-fat diet-induced NAFLD by increasing glycolysis, OXPHOS, and pyroptosis in macrophages

ER stress mediates Angiotensin II-augmented innate immunity memory and facilitates distinct susceptibilities of thoracic from abdominal aorta to aneurysm development

Approaching Inflammation Paradoxes-Proinflammatory Cytokine Blockages Induce Inflammatory Regulators

Tissue Treg Secretomes and Transcription Factors Shared With Stem Cells Contribute to a Treg Niche to Maintain Treg-Ness With 80% Innate Immune Pathways, and Functions of Immunosuppression and Tissue Repair

High expression of ETS2 predicts poor prognosis in acute myeloid leukemia and may guide treatment decisions

Editorial: Sex differences and cardiovascular therapeutics

Procaspase-1 patrolled to the nucleus of proatherogenic lipid LPC-activated human aortic endothelial cells induces ROS promoter CYP1B1 and strong inflammation

Editorial: Endothelial cells as innate immune cells

Innate immunity of vascular smooth muscle cells contributes to two-wave inflammation in atherosclerosis, twin-peak inflammation in aortic aneurysms and trans-differentiation potential into 25 cell types

End-stage renal disease is different from chronic kidney disease in upregulating ROS-modulated proinflammatory secretome in PBMCs - A novel multiple-hit model for disease progression

Aorta in Pathologies May Function as an Immune Organ by Upregulating Secretomes for Immune and Vascular Cell Activation, Differentiation and Trans-Differentiation-Early Secretomes may Serve as Drivers for Trained Immunity

Chronic Exposure to the Combination of Cigarette Smoke and Morphine Decreases CD4 + Regulatory T Cell Numbers by Reprogramming the Treg Cell Transcriptome

Early hyperlipidemia triggers metabolomic reprogramming with increased SAH, increased acetyl-CoA-cholesterol synthesis, and decreased glycolysis

Hyperlipidemia May Synergize with Hypomethylation in Establishing Trained Immunity and Promoting Inflammation in NASH and NAFLD

Ultrasound May Suppress Tumor Growth, Inhibit Inflammation, and Establish Tolerogenesis by Remodeling Innatome via Pathways of ROS, Immune Checkpoints, Cytokines, and Trained Immunity/Tolerance

IL-35 promotes CD4+Foxp3+ Tregs and inhibits atherosclerosis via maintaining CCR5-amplified Treg-suppressive mechanisms

Canonical Secretomes, Innate Immune Caspase-1-, 4/11-Gasdermin D Non-Canonical Secretomes and Exosomes May Contribute to Maintain Treg-Ness for Treg Immunosuppression, Tissue Repair and Modulate Anti-Tumor Immunity via ROS Pathways

A Novel Subset of CD95 + Pro-Inflammatory Macrophages Overcome miR155 Deficiency and May Serve as a Switch From Metabolically Healthy Obesity to Metabolically Unhealthy Obesity

29 m6A-RNA Methylation (Epitranscriptomic) Regulators Are Regulated in 41 Diseases including Atherosclerosis and Tumors Potentially via ROS Regulation – 102 Transcriptomic Dataset Analyses

High expression of CPNE3 predicts adverse prognosis in acute myeloid leukemia

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