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Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models

PloS one, 2012-02, Vol.7 (2), p.e30555-e30555

2012

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Synthesis and biological evaluation of benzocyclobutane-C-glycosides as potent and orally active SGLT1/SGLT2 dual inhibitors

Bioorganic & medicinal chemistry letters, 2018-04, Vol.28 (7), p.1182-1187

2018

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A phase II study on Mefatinib as first-line treatment of patients with advanced non-small-cell lung cancer harboring uncommon EGFR mutations

Cancer communications (London, England), 2023-09, Vol.43 (9), p.1059-1063

2023

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GRK Inhibition Potentiates Glucagon-Like Peptide-1 Action

Frontiers in endocrinology (Lausanne), 2021-05, Vol.12, p.652628-652628

2021

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810 Preliminary safety, tolerability and efficacy results of KN026 in combination with KN046 in patients with HER2 aberrated solid tumors

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A485-A486

2020

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Numerical Simulation-Based Design: Theory and Methods

1st ed. 2020., 2020

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Abstract 1660: Preliminary safety tolerability & efficacy results of KN046 (an anti-PD-L1/CTLA-4 bispecific antibody) in combination with Nab-paclitaxel in patients with metastatic triple-negative breast cancer (mTNBC)

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1660-1660

2021

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Synthesis and structure–activity relationships of thiadiazole-derivatives as potent and orally active peroxisome proliferator-activated receptors α/δ dual agonists

Bioorganic & medicinal chemistry, 2008-03, Vol.16 (6), p.3321-3341

2008

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5,5-Difluoro- and 5-Fluoro-5-methyl-hexose-based C-Glucosides as potent and orally bioavailable SGLT1 and SGLT2 dual inhibitors

Bioorganic & medicinal chemistry letters, 2020-09, Vol.30 (17), p.127387-127387, Article 127387

2020

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A phase 2, open-label, multicenter study to evaluate the efficacy, safety, and tolerability of KN046 in combination with chemotherapy in subjects with advanced non-small cell lung cancer

Journal of clinical oncology, 2021-05, Vol.39 (15_suppl), p.9060-9060

2021

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Mefatinib as first-line treatment of patients with advanced non–small cell lung cancer harboring rare EGFR mutations

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.9102-9102

2022

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EP323/#463 Efficacy and safety of mirvetuximab soravtansine in Chinese patients with platinum-resistant ovarian cancer with high folate receptor alpha expression: results from IMGN853–301 (Soraya China) study

International journal of gynecological cancer, 2023-11, Vol.33 (Suppl 4), p.A210-A210

2023

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The preliminary efficacy and safety data of KN046 in patients failed on prior immune checkpoint inhibitors therapy

Journal of clinical oncology, 2020-05, Vol.38 (15_suppl), p.3020-3020

2020

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Preliminary safety, efficacy and pharmacokinetics (PK) results of KN026, a HER2 bispecific antibody in patients (pts) with HER2-positive metastatic breast cancer

Journal of clinical oncology, 2020-05, Vol.38 (15_suppl), p.1041-1041

2020

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Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors

Bioorganic & medicinal chemistry letters, 2018-11, Vol.28 (21), p.3446-3453

2018

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Hit-to-lead optimization and discovery of a potent, and orally bioavailable G protein coupled receptor kinase 2 (GRK2) inhibitor

Bioorganic & medicinal chemistry letters, 2020-12, Vol.30 (23), p.127602-127602, Article 127602

2020

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Preliminary safety, efficacy, and pharmacokinetics (PK) results of KN046 (bispecific anti-PD-L1/CTLA4) from a first-in-human study in subjects with advanced solid tumors

Journal of clinical oncology, 2019-05, Vol.37 (15_suppl), p.2554-2554

2019

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Blood digital polymerase chain reaction as a potential method to detect human epidermal growth factor receptor 2 amplification in non-small cell lung cancer

Translational lung cancer research, 2021-11, Vol.10 (11), p.4235-4249

2021

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Design and synthesis of indane-ureido-thioisobutyric acids: A novel class of PPARα agonists

Bioorganic & medicinal chemistry letters, 2007-12, Vol.17 (24), p.6773-6778

2007

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339 Preliminary safety, tolerability and efficacy results of KN026 (a HER2-targeted Bispecific Antibody) in combination with KN046 (an anti-PD-L1/CTLA-4 Bispecific Antibody) in patients (pts) with HER2 aberrated solid tumors

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A207-A207

2020

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Discovery of a novel potent GPR40 full agonist

Bioorganic & medicinal chemistry letters, 2018-02, Vol.28 (4), p.720-726

2018

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CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance

Cell reports. Medicine, 2023-02, Vol.4 (2), p.100917-100917, Article 100917

2023

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Crowdsourcing the Perception of Machine Teaching

Proceedings of the 2020 CHI Conference on Human Factors in Computing Systems, 2020, p.301-301

2020

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Exploring Machine Teaching for Object Recognition with the Crowd

Extended Abstracts of the 2019 CHI Conference on Human Factors in Computing Systems, 2019, p.1-6

2019

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Design and synthesis of indane-ureido-thioisobutyric acids: A novel class of PPARalpha agonists

Bioorganic & medicinal chemistry letters, 2007-12, Vol.17 (24), p.6773-6778

2007

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Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models

Synthesis and biological evaluation of benzocyclobutane-C-glycosides as potent and orally active SGLT1/SGLT2 dual inhibitors

A phase II study on Mefatinib as first-line treatment of patients with advanced non-small-cell lung cancer harboring uncommon EGFR mutations

GRK Inhibition Potentiates Glucagon-Like Peptide-1 Action

810 Preliminary safety, tolerability and efficacy results of KN026 in combination with KN046 in patients with HER2 aberrated solid tumors

Numerical Simulation-Based Design: Theory and Methods

Abstract 1660: Preliminary safety tolerability & efficacy results of KN046 (an anti-PD-L1/CTLA-4 bispecific antibody) in combination with Nab-paclitaxel in patients with metastatic triple-negative breast cancer (mTNBC)

Synthesis and structure–activity relationships of thiadiazole-derivatives as potent and orally active peroxisome proliferator-activated receptors α/δ dual agonists

5,5-Difluoro- and 5-Fluoro-5-methyl-hexose-based C-Glucosides as potent and orally bioavailable SGLT1 and SGLT2 dual inhibitors

A phase 2, open-label, multicenter study to evaluate the efficacy, safety, and tolerability of KN046 in combination with chemotherapy in subjects with advanced non-small cell lung cancer

Mefatinib as first-line treatment of patients with advanced non–small cell lung cancer harboring rare EGFR mutations

EP323/#463 Efficacy and safety of mirvetuximab soravtansine in Chinese patients with platinum-resistant ovarian cancer with high folate receptor alpha expression: results from IMGN853–301 (Soraya China) study

The preliminary efficacy and safety data of KN046 in patients failed on prior immune checkpoint inhibitors therapy

Preliminary safety, efficacy and pharmacokinetics (PK) results of KN026, a HER2 bispecific antibody in patients (pts) with HER2-positive metastatic breast cancer

Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors

Hit-to-lead optimization and discovery of a potent, and orally bioavailable G protein coupled receptor kinase 2 (GRK2) inhibitor

Preliminary safety, efficacy, and pharmacokinetics (PK) results of KN046 (bispecific anti-PD-L1/CTLA4) from a first-in-human study in subjects with advanced solid tumors

Blood digital polymerase chain reaction as a potential method to detect human epidermal growth factor receptor 2 amplification in non-small cell lung cancer

Design and synthesis of indane-ureido-thioisobutyric acids: A novel class of PPARα agonists

339 Preliminary safety, tolerability and efficacy results of KN026 (a HER2-targeted Bispecific Antibody) in combination with KN046 (an anti-PD-L1/CTLA-4 Bispecific Antibody) in patients (pts) with HER2 aberrated solid tumors

Discovery of a novel potent GPR40 full agonist

CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance

Crowdsourcing the Perception of Machine Teaching

Exploring Machine Teaching for Object Recognition with the Crowd

Design and synthesis of indane-ureido-thioisobutyric acids: A novel class of PPARalpha agonists

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