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Ferroptosis in the tumor microenvironment: perspectives for immunotherapy

Trends in molecular medicine, 2021-09, Vol.27 (9), p.856-867

2021

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Cholesterol metabolism: New functions and therapeutic approaches in cancer

Biochimica et biophysica acta. Reviews on cancer, 2020-08, Vol.1874 (1), p.188394-188394, Article 188394

2020

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Ursodeoxycholic acid suppresses the malignant progression of colorectal cancer through TGR5-YAP axis

Cell death discovery, 2021-08, Vol.7 (1), p.207-207, Article 207

2021

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Targeting sterol-O-acyltransferase 1 to disrupt cholesterol metabolism for cancer therapy

Frontiers in oncology, 2023-06, Vol.13, p.1197502-1197502

2023

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MEK nuclear localization promotes YAP stability via sequestering β-TrCP in KRAS mutant cancer cells

Cell death and differentiation, 2019-11, Vol.26 (11), p.2400-2415

2019

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Acetylcholine acts through M3 muscarinic receptor to activate the EGFR signaling and promotes gastric cancer cell proliferation

Scientific reports, 2017-01, Vol.7 (1), p.40802-40802, Article 40802

2017

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Casp8 acts through A20 to inhibit PD‐L1 expression: The mechanism and its implication in immunotherapy

Cancer science, 2021-07, Vol.112 (7), p.2664-2678

2021

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Cholesterol activates the Wnt/PCP-YAP signaling in SOAT1-targeted treatment of colon cancer

Cell death discovery, 2021-02, Vol.7 (1), p.38-13, Article 38

2021

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Autophagic sequestration of SQSTM1 disrupts the aggresome formation of ubiquitinated proteins during proteasome inhibition

Cell death & disease, 2022-07, Vol.13 (7), p.615-615, Article 615

2022

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Targeting the key cholesterol biosynthesis enzyme squalene monooxygenasefor cancer therapy

Frontiers in oncology, 2022-08, Vol.12, p.938502-938502

2022

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Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis

Cell death discovery, 2021-05, Vol.7 (1), p.125-125, Article 125

2021

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Targeting SERT promotes tryptophan metabolism: mechanisms and implications in colon cancer treatment

Journal of experimental & clinical cancer research, 2021-05, Vol.40 (1), p.173-173, Article 173

2021

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Inhibition of stress proteins TRIB3 and STC2 potentiates sorafenib sensitivity in hepatocellular carcinoma

Heliyon, 2023-06, Vol.9 (6), p.e17295-e17295, Article e17295

2023

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ERRα suppression enhances the cytotoxicity of the MEK inhibitor trametinib against colon cancer cells

Journal of experimental & clinical cancer research, 2018-09, Vol.37 (1), p.218-14, Article 218

2018

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Endogenous Coriobacteriaceae enriched by a high-fat diet promotes colorectal tumorigenesis through the CPT1A-ERK axis

NPJ biofilms and microbiomes, 2024-01, Vol.10 (1), p.5-5, Article 5

2024

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Standard CD44 modulates YAP1 through a positive feedback loop in hepatocellular carcinoma

Biomedicine & pharmacotherapy, 2018-07, Vol.103, p.147-156

2018

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Regulation of Ferroptosis by Amino Acid Metabolism in Cancer

International journal of biological sciences, 2022-01, Vol.18 (4), p.1695-1705

2022

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Dipyridamole Enhances the Cytotoxicities of Trametinib against Colon Cancer Cells through Combined Targeting of HMGCS1 and MEK Pathway

Molecular cancer therapeutics, 2020-01, Vol.19 (1), p.135-146

2020

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PKM2 compensates for proteasome dysfunction by mediating the formation of the CHIP‐HSP70‐BAG3 complex and the aggregation of ubiquitinated proteins

The FASEB journal, 2022-01, Vol.36 (1), p.e22121-n/a

2022

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Identification and characterization of inhibitory nanobody against p38δ

Biochemical and biophysical research communications, 2022-04, Vol.600, p.60-66

2022

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Ferroptosis signaling promotes the release of misfolded proteins via exosomes to rescue ER stress in hepatocellular carcinoma

Free radical biology & medicine, 2023-06, Vol.202, p.110-120

2023

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The selective serotonin reuptake inhibitors enhance the cytotoxicity of sorafenib in hepatocellular carcinoma cells

Anti-cancer drugs, 2021-09, Vol.32 (8), p.793-801

2021

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The role of 5-HT metabolism in cancer

Biochimica et biophysica acta. Reviews on cancer, 2021-12, Vol.1876 (2), p.188618-188618, Article 188618

2021

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CaMKII suppresses proteotoxicity by phosphorylating BAG3 in response to proteasomal dysfunction

EMBO reports, 2024-10, Vol.25 (10), p.4488-4514

2024

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Survival mechanisms of circulating tumor cells and their implications for cancer treatment

Cancer and metastasis reviews, 2024-09, Vol.43 (3), p.941-957

2024

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Ferroptosis in the tumor microenvironment: perspectives for immunotherapy

Cholesterol metabolism: New functions and therapeutic approaches in cancer

Ursodeoxycholic acid suppresses the malignant progression of colorectal cancer through TGR5-YAP axis

Targeting sterol-O-acyltransferase 1 to disrupt cholesterol metabolism for cancer therapy

MEK nuclear localization promotes YAP stability via sequestering β-TrCP in KRAS mutant cancer cells

Acetylcholine acts through M3 muscarinic receptor to activate the EGFR signaling and promotes gastric cancer cell proliferation

Casp8 acts through A20 to inhibit PD‐L1 expression: The mechanism and its implication in immunotherapy

Cholesterol activates the Wnt/PCP-YAP signaling in SOAT1-targeted treatment of colon cancer

Autophagic sequestration of SQSTM1 disrupts the aggresome formation of ubiquitinated proteins during proteasome inhibition

Targeting the key cholesterol biosynthesis enzyme squalene monooxygenasefor cancer therapy

Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis

Targeting SERT promotes tryptophan metabolism: mechanisms and implications in colon cancer treatment

Inhibition of stress proteins TRIB3 and STC2 potentiates sorafenib sensitivity in hepatocellular carcinoma

ERRα suppression enhances the cytotoxicity of the MEK inhibitor trametinib against colon cancer cells

Endogenous Coriobacteriaceae enriched by a high-fat diet promotes colorectal tumorigenesis through the CPT1A-ERK axis

Standard CD44 modulates YAP1 through a positive feedback loop in hepatocellular carcinoma

Regulation of Ferroptosis by Amino Acid Metabolism in Cancer

Dipyridamole Enhances the Cytotoxicities of Trametinib against Colon Cancer Cells through Combined Targeting of HMGCS1 and MEK Pathway

PKM2 compensates for proteasome dysfunction by mediating the formation of the CHIP‐HSP70‐BAG3 complex and the aggregation of ubiquitinated proteins

Identification and characterization of inhibitory nanobody against p38δ

Ferroptosis signaling promotes the release of misfolded proteins via exosomes to rescue ER stress in hepatocellular carcinoma

The selective serotonin reuptake inhibitors enhance the cytotoxicity of sorafenib in hepatocellular carcinoma cells

The role of 5-HT metabolism in cancer

CaMKII suppresses proteotoxicity by phosphorylating BAG3 in response to proteasomal dysfunction

Survival mechanisms of circulating tumor cells and their implications for cancer treatment

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