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Molecular and Synaptic Bases of CDKL5 Disorder

Developmental neurobiology (Hoboken, N.J.), 2019-01, Vol.79 (1), p.8-19

2019

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China Brain Project: Basic Neuroscience, Brain Diseases, and Brain-Inspired Computing

Neuron (Cambridge, Mass.), 2016-11, Vol.92 (3), p.591-596

2016

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Excessive UBE3A dosage impairs retinoic acid signaling and synaptic plasticity in autism spectrum disorders

Cell research, 2018-01, Vol.28 (1), p.48-68

2018

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KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells

Oncogene, 2018-05, Vol.37 (22), p.2936-2952

2018

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CDKL5 deficiency in forebrain glutamatergic neurons results in recurrent spontaneous seizures

Epilepsia (Copenhagen), 2021-02, Vol.62 (2), p.517-528

2021

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Biallelic Mutations in MYORG Cause Autosomal Recessive Primary Familial Brain Calcification

Neuron (Cambridge, Mass.), 2018-06, Vol.98 (6), p.1116-1123.e5

2018

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Rethinking monogenic neurological diseases

BMJ (Online), 2020-10, p.m3752

2020

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PSD-93 up-regulates the synaptic activity of corticotropin-releasing hormone neurons in the paraventricular nucleus in depression

Acta neuropathologica, 2021-12, Vol.142 (6), p.1045-1064

2021

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Zinc-Mediated Transactivation of TrkB Potentiates the Hippocampal Mossy Fiber-CA3 Pyramid Synapse

Neuron (Cambridge, Mass.), 2008-02, Vol.57 (4), p.546-558

2008

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Neuregulin 1 represses limbic epileptogenesis through ErbB4 in parvalbumin-expressing interneurons

Nature neuroscience, 2012-02, Vol.15 (2), p.258-266

2012

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Low-intensity ultrasound directly modulates neural activity of the cerebellar cortex

Brain stimulation, 2023-05, Vol.16 (3), p.918-926

2023

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Palmitoylation-dependent CDKL5–PSD-95 interaction regulates synaptic targeting of CDKL5 and dendritic spine development

Proceedings of the National Academy of Sciences - PNAS, 2013-05, Vol.110 (22), p.9118-9123

2013

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UBE3A-mediated PTPA ubiquitination and degradation regulate PP2A activity and dendritic spine morphology

Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (25), p.12500-12505

2019

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CDKL5 deficiency in adult glutamatergic neurons alters synaptic activity and causes spontaneous seizures via TrkB signaling

Cell reports (Cambridge), 2023-10, Vol.42 (10), p.113202-113202, Article 113202

2023

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HAP1 is an in vivo UBE3A target that augments autophagy in a mouse model of Angelman syndrome

Neurobiology of disease, 2019-12, Vol.132, p.104585-104585, Article 104585

2019

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TORC1 Regulates Activity-Dependent CREB-Target Gene Transcription and Dendritic Growth of Developing Cortical Neurons

The Journal of neuroscience, 2009-02, Vol.29 (8), p.2334-2343

2009

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Targeting KPNB1 overcomes TRAIL resistance by regulating DR5, Mcl-1 and FLIP in glioblastoma cells

Cell death & disease, 2019-02, Vol.10 (2), p.118-118, Article 118

2019

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XPO1 inhibitor KPT-330 synergizes with Bcl-xL inhibitor to induce cancer cell apoptosis by perturbing rRNA processing and Mcl-1 protein synthesis

Cell death & disease, 2019-05, Vol.10 (6), p.395, Article 395

2019

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Angelman Syndrome Protein Ube3a Regulates Synaptic Growth and Endocytosis by Inhibiting BMP Signaling in Drosophila

PLoS genetics, 2016-05, Vol.12 (5), p.e1006062-e1006062

2016

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Differential Roles of NMDA Receptor Subtypes in Ischemic Neuronal Cell Death and Ischemic Tolerance

Stroke (1970), 2008-11, Vol.39 (11), p.3042-3048

2008

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Stop-gain mutations in UBAP1 cause pure autosomal-dominant spastic paraplegia

Brain (London, England : 1878), 2019-08, Vol.142 (8), p.2238-2252

2019

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The Angelman syndrome protein Ube3a is required for polarized dendrite morphogenesis in pyramidal neurons

The Journal of neuroscience, 2013-01, Vol.33 (1), p.327-333

2013

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Cerebellar spreading depolarization mediates paroxysmal movement disorder

Cell reports (Cambridge), 2021-09, Vol.36 (12), p.109743-109743, Article 109743

2021

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The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons

Cell reports (Cambridge), 2016-08, Vol.16 (5), p.1431-1444

2016

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Identify mutation in amyotrophic lateral sclerosis cases using HaloPlex target enrichment system

Neurobiology of aging, 2014-12, Vol.35 (12), p.2881.e11-2881.e15

2014

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Molecular and Synaptic Bases of CDKL5 Disorder

China Brain Project: Basic Neuroscience, Brain Diseases, and Brain-Inspired Computing

Excessive UBE3A dosage impairs retinoic acid signaling and synaptic plasticity in autism spectrum disorders

KPNB1 inhibition disrupts proteostasis and triggers unfolded protein response-mediated apoptosis in glioblastoma cells

CDKL5 deficiency in forebrain glutamatergic neurons results in recurrent spontaneous seizures

Biallelic Mutations in MYORG Cause Autosomal Recessive Primary Familial Brain Calcification

Rethinking monogenic neurological diseases

PSD-93 up-regulates the synaptic activity of corticotropin-releasing hormone neurons in the paraventricular nucleus in depression

Zinc-Mediated Transactivation of TrkB Potentiates the Hippocampal Mossy Fiber-CA3 Pyramid Synapse

Neuregulin 1 represses limbic epileptogenesis through ErbB4 in parvalbumin-expressing interneurons

Low-intensity ultrasound directly modulates neural activity of the cerebellar cortex

Palmitoylation-dependent CDKL5–PSD-95 interaction regulates synaptic targeting of CDKL5 and dendritic spine development

UBE3A-mediated PTPA ubiquitination and degradation regulate PP2A activity and dendritic spine morphology

CDKL5 deficiency in adult glutamatergic neurons alters synaptic activity and causes spontaneous seizures via TrkB signaling

HAP1 is an in vivo UBE3A target that augments autophagy in a mouse model of Angelman syndrome

TORC1 Regulates Activity-Dependent CREB-Target Gene Transcription and Dendritic Growth of Developing Cortical Neurons

Targeting KPNB1 overcomes TRAIL resistance by regulating DR5, Mcl-1 and FLIP in glioblastoma cells

XPO1 inhibitor KPT-330 synergizes with Bcl-xL inhibitor to induce cancer cell apoptosis by perturbing rRNA processing and Mcl-1 protein synthesis

Angelman Syndrome Protein Ube3a Regulates Synaptic Growth and Endocytosis by Inhibiting BMP Signaling in Drosophila

Differential Roles of NMDA Receptor Subtypes in Ischemic Neuronal Cell Death and Ischemic Tolerance

Stop-gain mutations in UBAP1 cause pure autosomal-dominant spastic paraplegia

The Angelman syndrome protein Ube3a is required for polarized dendrite morphogenesis in pyramidal neurons

Cerebellar spreading depolarization mediates paroxysmal movement disorder

The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons

Identify mutation in amyotrophic lateral sclerosis cases using HaloPlex target enrichment system

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