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Species differences in drug transporters and implications for translating preclinical findings to humans

Expert opinion on drug metabolism & toxicology, 2013-03, Vol.9 (3), p.237-252

2013

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Identification of Endogenous Biomarkers to Predict the Propensity of Drug Candidates to Cause Hepatic or Renal Transporter-Mediated Drug-Drug Interactions

Journal of pharmaceutical sciences, 2017-09, Vol.106 (9), p.2357-2367

2017

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A Review of Artificial Intelligence (AI) in Education from 2010 to 2020

Complexity (New York, N.Y.), 2021, Vol.2021 (1)

2021

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Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug‐Drug Interaction Evaluation: Perspectives From the International Transporter Consortium

Clinical pharmacology and therapeutics, 2018-11, Vol.104 (5), p.836-864

2018

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Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance

Clinical pharmacology and therapeutics, 2018-11, Vol.104 (5), p.890-899

2018

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Physiologically‐Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug–Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Recommendations

Clinical pharmacology and therapeutics, 2020-05, Vol.107 (5), p.1082-1115

2020

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Interspecies variability in expression of hepatobiliary transporters across human, dog, monkey, and rat as determined by quantitative proteomics

Drug metabolism and disposition, 2015-03, Vol.43 (3), p.367-374

2015

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Fault diagnosis for the motor drive system of urban transit based on improved Hidden Markov Model

Microelectronics and reliability, 2018-03, Vol.82, p.179-189

2018

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Advancing Predictions of Tissue and Intracellular Drug Concentrations Using In Vitro, Imaging and Physiologically Based Pharmacokinetic Modeling Approaches

Clinical pharmacology and therapeutics, 2018-11, Vol.104 (5), p.865-889

2018

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Interindividual and Regional Variability in Drug Transporter Abundance at the Human Blood–Brain Barrier Measured by Quantitative Targeted Proteomics

Clinical pharmacology and therapeutics, 2019-07, Vol.106 (1), p.228-237

2019

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Dabigatran Etexilate and Digoxin: Comparison as Clinical Probe Substrates for Evaluation of P‐gp Inhibition

Clinical pharmacology and therapeutics, 2018-11, Vol.104 (5), p.788-792

2018

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Drug–Drug Interaction Studies: Regulatory Guidance and An Industry Perspective

The AAPS journal, 2013-07, Vol.15 (3), p.629-645

2013

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Pitavastatin is a more sensitive and selective organic anion‐transporting polypeptide 1B clinical probe than rosuvastatin

British journal of clinical pharmacology, 2014-09, Vol.78 (3), p.587-598

2014

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Abundance of Phase 1 and 2 Drug-Metabolizing Enzymes in Alcoholic and Hepatitis C Cirrhotic Livers: A Quantitative Targeted Proteomics Study

Drug metabolism and disposition, 2018-07, Vol.46 (7), p.943-952

2018

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Intestinal P‐gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications

Clinical pharmacology and therapeutics, 2021-01, Vol.109 (1), p.55-64

2021

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Positron Emission Tomography Imaging of [11C]Rosuvastatin Hepatic Concentrations and Hepatobiliary Transport in Humans in the Absence and Presence of Cyclosporin A

Clinical pharmacology and therapeutics, 2019-11, Vol.106 (5), p.1056-1066

2019

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Absorption, Metabolism, Distribution, and Excretion of Letermovir

Current drug metabolism, 2021-08, Vol.22 (10), p.784-794

2021

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Knockdown of ARHGAP30 inhibits ovarian cancer cell proliferation, migration, and invasiveness by suppressing the PI3K/AKT/mTOR signaling pathway

European journal of histochemistry, 2023-05, Vol.67 (2)

2023

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A Comparison of Total and Plasma Membrane Abundance of Transporters in Suspended, Plated, Sandwich-Cultured Human Hepatocytes Versus Human Liver Tissue Using Quantitative Targeted Proteomics and Cell Surface Biotinylation

Drug metabolism and disposition, 2019-04, Vol.47 (4), p.350-357

2019

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Acute and Chronic Effects of Rifampin on Letermovir Suggest Transporter Inhibition and Induction Contribute to Letermovir Pharmacokinetics

Clinical pharmacology and therapeutics, 2022-03, Vol.111 (3), p.664-675

2022

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Recent advances in the translation of drug metabolism and pharmacokinetics science for drug discovery and development

Acta pharmaceutica Sinica. B, 2022-06, Vol.12 (6), p.2751-2777

2022

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Fabrication of cervical squamous cell carcinoma antigen immunosensor using graphene-polymer composites

Alexandria engineering journal, 2024-02, Vol.88, p.182-188

2024

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The Effect of Multi-mode Stimuli of Feedforward and Eye Tracking on Metacognition-An Exploratory Study Using Digital Dictionaries

Educational Technology ＆ Society, 2022-01, Vol.25 (1), p.213-227

2022

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Tea polyphenols attenuate liver inflammation by modulating obesity-related genes and down-regulating COX-2 and iNOS expression in high fat-fed dogs

BMC veterinary research, 2020-07, Vol.16 (1), p.234-12, Article 234

2020

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Robust Decentralized Fault Estimation for Loss of Actuator Effectiveness of Multi-motor Web-winding System

International Journal of Control, 2019, Automation, and Systems, 17(3), , pp.691-704

2019

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Species differences in drug transporters and implications for translating preclinical findings to humans

Identification of Endogenous Biomarkers to Predict the Propensity of Drug Candidates to Cause Hepatic or Renal Transporter-Mediated Drug-Drug Interactions

A Review of Artificial Intelligence (AI) in Education from 2010 to 2020

Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug‐Drug Interaction Evaluation: Perspectives From the International Transporter Consortium

Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance

Physiologically‐Based Pharmacokinetic Models for Evaluating Membrane Transporter Mediated Drug–Drug Interactions: Current Capabilities, Case Studies, Future Opportunities, and Recommendations

Interspecies variability in expression of hepatobiliary transporters across human, dog, monkey, and rat as determined by quantitative proteomics

Fault diagnosis for the motor drive system of urban transit based on improved Hidden Markov Model

Advancing Predictions of Tissue and Intracellular Drug Concentrations Using In Vitro, Imaging and Physiologically Based Pharmacokinetic Modeling Approaches

Interindividual and Regional Variability in Drug Transporter Abundance at the Human Blood–Brain Barrier Measured by Quantitative Targeted Proteomics

Dabigatran Etexilate and Digoxin: Comparison as Clinical Probe Substrates for Evaluation of P‐gp Inhibition

Drug–Drug Interaction Studies: Regulatory Guidance and An Industry Perspective

Pitavastatin is a more sensitive and selective organic anion‐transporting polypeptide 1B clinical probe than rosuvastatin

Abundance of Phase 1 and 2 Drug-Metabolizing Enzymes in Alcoholic and Hepatitis C Cirrhotic Livers: A Quantitative Targeted Proteomics Study

Intestinal P‐gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications

Positron Emission Tomography Imaging of [11C]Rosuvastatin Hepatic Concentrations and Hepatobiliary Transport in Humans in the Absence and Presence of Cyclosporin A

Absorption, Metabolism, Distribution, and Excretion of Letermovir

Knockdown of ARHGAP30 inhibits ovarian cancer cell proliferation, migration, and invasiveness by suppressing the PI3K/AKT/mTOR signaling pathway

A Comparison of Total and Plasma Membrane Abundance of Transporters in Suspended, Plated, Sandwich-Cultured Human Hepatocytes Versus Human Liver Tissue Using Quantitative Targeted Proteomics and Cell Surface Biotinylation

Acute and Chronic Effects of Rifampin on Letermovir Suggest Transporter Inhibition and Induction Contribute to Letermovir Pharmacokinetics

Recent advances in the translation of drug metabolism and pharmacokinetics science for drug discovery and development

Fabrication of cervical squamous cell carcinoma antigen immunosensor using graphene-polymer composites

The Effect of Multi-mode Stimuli of Feedforward and Eye Tracking on Metacognition-An Exploratory Study Using Digital Dictionaries

Tea polyphenols attenuate liver inflammation by modulating obesity-related genes and down-regulating COX-2 and iNOS expression in high fat-fed dogs

Robust Decentralized Fault Estimation for Loss of Actuator Effectiveness of Multi-motor Web-winding System

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