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Room-temperature enantioselective C–H iodination via kinetic resolution

Science (American Association for the Advancement of Science), 2014-10, Vol.346 (6208), p.451-455

2014

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Enantioselective C−H Olefination of α-Hydroxy and α-Amino Phenylacetic Acids by Kinetic Resolution

Angewandte Chemie International Edition, 2016-02, Vol.55 (8), p.2856-2860

2016

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Ligand-Enabled Arylation of γ-C−H Bonds

Angewandte Chemie International Edition, 2016-03, Vol.55 (13), p.4317-4321

International ed. in English, 2016

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Pd(II)-Catalyzed Phosphorylation of Aryl C–H Bonds

Journal of the American Chemical Society, 2013-06, Vol.135 (25), p.9322-9325

2013

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Direct Transformation of Secondary Amides into Secondary Amines: Triflic Anhydride Activated Reductive Alkylation

Angewandte Chemie International Edition, 2012-08, Vol.51 (33), p.8314-8317

International ed. in English, 2012

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Kinetic Resolution of Benzylamines via Palladium(II)-Catalyzed C–H Cross-Coupling

Journal of the American Chemical Society, 2016-06, Vol.138 (24), p.7796-7800

2016

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Palladium(II)-Catalyzed Enantioselective C(sp3)–H Activation Using a Chiral Hydroxamic Acid Ligand

Journal of the American Chemical Society, 2014-06, Vol.136 (22), p.8138-8142

2014

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Direct, One-pot Sequential Reductive Alkylation of Lactams/Amides with Grignard and Organolithium Reagents through Lactam/Amide Activation

Angewandte Chemie (International ed.), 2010-04, Vol.49 (17), p.3037-3040

2010

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General One-Pot Reductive gem-Bis-Alkylation of Tertiary Lactams/Amides: Rapid Construction of 1-Azaspirocycles and Formal Total Synthesis of (±)-Cephalotaxine

Chemistry : a European journal, 2013-09, Vol.19 (39), p.13075-13086

2013

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A General Method for the One-Pot Reductive Functionalization of Secondary Amides

Journal of organic chemistry, 2015-03, Vol.80 (5), p.2861-2868

2015

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Versatile One-Pot Reductive Alkylation of Lactams/Amides via Amide Activation: Application to the Concise Syntheses of Bioactive Alkaloids (±)-Bgugaine, (±)-Coniine, (+)-Preussin, and (−)-Cassine

Chemistry : a European journal, 2010-11, Vol.16 (43), p.12792-12796

2010

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A Direct and General Method for the Reductive Alkylation of Tertiary Lactams/Amides: Application to the Step Economical Synthesis of Alkaloid (−)-Morusimic Acid D

Journal of organic chemistry, 2013-09, Vol.78 (17), p.8305-8311

2013

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Tertiary amide-based Knoevenagel-type reactions: a direct, general, and chemoselective approach to enaminones

Chemical communications (Cambridge, England), 2014-07, Vol.50 (63), p.8761

2014

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Versatile and Direct Transformation of Secondary Amides into Ketones by Deaminative Alkylation with Organocerium Reagents

Asian journal of organic chemistry, 2012-10, Vol.1 (2), p.130-132

2012

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Metal-Free Intermolecular Coupling of Arenes with Secondary Amides: Chemoselective Synthesis of Aromatic Ketimines and Ketones, and N‑Deacylation of Secondary Amides

Journal of organic chemistry, 2016-10, Vol.81 (19), p.9020-9027

2016

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The first enantioselective total synthesis of（＋）-preussin B and an improved synthesis of（＋）-preussin by step-economical methods

Science China. Chemistry, 2015-03, Vol.58 (3), p.478-482

2015

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Benzylic Photobromination for the Synthesis of Belzutifan: Elucidation of Reaction Mechanisms Using In Situ LED-NMR

Journal of organic chemistry, 2022-02, Vol.87 (4), p.2055-2062

2022

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A general method for the direct transformation of common tertiary amides into ketones and amines by addition of Grignard reagents

Tetrahedron, 2015-06, Vol.71 (24), p.4248-4254

2015

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Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2

Journal of medicinal chemistry, 2024-02, Vol.67 (4), p.3112-3126

2024

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Pilot-Scale Operation and Characterization of an Organolithium-Mediated Coupling Reaction in Flow to Form a Ketone Intermediate on the Route to Nemtabrutinib

Organic process research & development, 2024-05, Vol.28 (5), p.1411-1421

2024

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Development of a Green and Sustainable Manufacturing Process for a Key Intermediate to Nemtabrutinib (MK-1026): Sequential Deprotonation–Lithiation as a Batch–Flow Process

Organic process research & development, 2024-05, Vol.28 (5), p.1402-1410

2024

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An enantioselective synthesis of (+)-azimic acid

Tetrahedron: asymmetry, 2009-06, Vol.20 (10), p.1181-1184

2009

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Ligand-Enabled Arylation of γ-C−H Bonds

Angewandte Chemie, 2016-03, Vol.128 (13), p.4389-4393

2016

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A concise and divergent approach to radicamine B and hyacinthacine A3 based on a step-economic transformation

Tetrahedron, 2012-07, Vol.68 (26), p.5297-5302

2012

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Chemo- and diastereoselective control for a flexible approach to (5 S,6 S)-6-alkyl-5-benzyloxy-2-piperidinones

Tetrahedron, 2009-05, Vol.65 (19), p.3834-3841

2009

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Room-temperature enantioselective C–H iodination via kinetic resolution

Enantioselective C−H Olefination of α-Hydroxy and α-Amino Phenylacetic Acids by Kinetic Resolution

Ligand-Enabled Arylation of γ-C−H Bonds

Pd(II)-Catalyzed Phosphorylation of Aryl C–H Bonds

Direct Transformation of Secondary Amides into Secondary Amines: Triflic Anhydride Activated Reductive Alkylation

Kinetic Resolution of Benzylamines via Palladium(II)-Catalyzed C–H Cross-Coupling

Palladium(II)-Catalyzed Enantioselective C(sp3)–H Activation Using a Chiral Hydroxamic Acid Ligand

Direct, One-pot Sequential Reductive Alkylation of Lactams/Amides with Grignard and Organolithium Reagents through Lactam/Amide Activation

General One-Pot Reductive gem-Bis-Alkylation of Tertiary Lactams/Amides: Rapid Construction of 1-Azaspirocycles and Formal Total Synthesis of (±)-Cephalotaxine

A General Method for the One-Pot Reductive Functionalization of Secondary Amides

Versatile One-Pot Reductive Alkylation of Lactams/Amides via Amide Activation: Application to the Concise Syntheses of Bioactive Alkaloids (±)-Bgugaine, (±)-Coniine, (+)-Preussin, and (−)-Cassine

A Direct and General Method for the Reductive Alkylation of Tertiary Lactams/Amides: Application to the Step Economical Synthesis of Alkaloid (−)-Morusimic Acid D

Tertiary amide-based Knoevenagel-type reactions: a direct, general, and chemoselective approach to enaminones

Versatile and Direct Transformation of Secondary Amides into Ketones by Deaminative Alkylation with Organocerium Reagents

Metal-Free Intermolecular Coupling of Arenes with Secondary Amides: Chemoselective Synthesis of Aromatic Ketimines and Ketones, and N‑Deacylation of Secondary Amides

The first enantioselective total synthesis of（＋）-preussin B and an improved synthesis of（＋）-preussin by step-economical methods

Benzylic Photobromination for the Synthesis of Belzutifan: Elucidation of Reaction Mechanisms Using In Situ LED-NMR

A general method for the direct transformation of common tertiary amides into ketones and amines by addition of Grignard reagents

Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2

Pilot-Scale Operation and Characterization of an Organolithium-Mediated Coupling Reaction in Flow to Form a Ketone Intermediate on the Route to Nemtabrutinib

Development of a Green and Sustainable Manufacturing Process for a Key Intermediate to Nemtabrutinib (MK-1026): Sequential Deprotonation–Lithiation as a Batch–Flow Process

An enantioselective synthesis of (+)-azimic acid

Ligand-Enabled Arylation of γ-C−H Bonds

A concise and divergent approach to radicamine B and hyacinthacine A3 based on a step-economic transformation

Chemo- and diastereoselective control for a flexible approach to (5 S,6 S)-6-alkyl-5-benzyloxy-2-piperidinones

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