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Function, mechanism and drug discovery of ubiquitin and ubiquitin-like modification with multiomics profiling for cancer therapy

Acta pharmaceutica Sinica. B, 2023-11, Vol.13 (11), p.4341-4372

2023

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Tryptanthrin targets GSTP1 to induce senescence and increases the susceptibility to apoptosis by senolytics in liver cancer cells

Redox biology, 2024-10, Vol.76, p.103323, Article 103323

2024

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Variants in the IL7RA gene confer susceptibility to multiple sclerosis in Caucasians: evidence based on 9734 cases and 10436 controls

Scientific reports, 2017-04, Vol.7 (1), p.1207-10, Article 1207

2017

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A(H2N2) and A(H3N2) influenza pandemics elicited durable cross-reactive and protective antibodies against avian N2 neuraminidases

Nature communications, 2024-07, Vol.15 (1), p.5593-15, Article 5593

2024

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Silibinin, a potential fasting mimetic, inhibits hepatocellular carcinoma by triggering extrinsic apoptosis

MedComm (2020), 2024-01, Vol.5 (1), p.e457-n/a

2024

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Andrographolide Inhibits ER-Positive Breast Cancer Growth and Enhances Fulvestrant Efficacy via ROS-FOXM1-ER-α Axis

Frontiers in oncology, 2022-05, Vol.12, p.899402-899402

2022

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Amino acids in the polymerase complex of shorebird-isolated H1N1 influenza virus impact replication and host-virus interactions in mammalian models

Emerging microbes & infections, 2024-12, Vol.13 (1), p.2332652-2332652

2024

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Non‐invasive omics analysis delineates molecular changes in water‐only fasting and its sex‐discriminating features in metabolic syndrome patients

MedComm (2020), 2023-12, Vol.4 (6), p.e393-n/a

2023

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Five‐day water‐only fasting decreased metabolic‐syndrome risk factors and increased anti‐aging biomarkers without toxicity in a clinical trial of normal‐weight individuals

Clinical and translational medicine, 2021-08, Vol.11 (8), p.e502-n/a

2021

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The Essential Role of Bond Energetics in C–H Activation/Functionalization

Chemical reviews, 2017-07, Vol.117 (13), p.8622-8648

2017

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Self-preservation strategy for approaching global warming targets in the post-Paris Agreement era

Nature communications, 2020-04, Vol.11 (1), p.1624-13, Article 1624

2020

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Grape seed procyanidin extract protects against Pb-induced lung toxicity by activating the AMPK/Nrf2/p62 signaling axis

Food and chemical toxicology, 2018-06, Vol.116 (Pt B), p.59-69

2018

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Uncertainties in the technological pathway towards low-carbon freight transport under carbon neutral target in China

Applied energy, 2024-07, Vol.365, p.123272, Article 123272

2024

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Regulation of Sirt1/Nrf2/TNF-α signaling pathway by luteolin is critical to attenuate acute mercuric chloride exposure induced hepatotoxicity

Scientific reports, 2016-11, Vol.6 (1), p.37157, Article 37157

2016

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NRF2 activation suppresses motor neuron ferroptosis induced by the SOD1G93A mutation and exerts neuroprotection in amyotrophic lateral sclerosis

Neurobiology of disease, 2023-08, Vol.184, p.106210-106210, Article 106210

2023

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Naringenin alleviates myocardial ischemia/reperfusion injury by regulating the nuclear factor-erythroid factor 2-related factor 2 (Nrf2) /System xc-/ glutathione peroxidase 4 (GPX4) axis to inhibit ferroptosis

Bioengineered, 2021-12, Vol.12 (2), p.10924-10934

2021

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Chiral Spiro Phosphoric Acid-Catalyzed Friedel–Crafts Conjugate Addition/Enantioselective Protonation Reactions

ACS catalysis, 2019-07, Vol.9 (7), p.6522-6529

2019

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Mechanism and Origins of Chemo- and Stereoselectivities of Aryl Iodide-Catalyzed Asymmetric Difluorinations of β-Substituted Styrenes

Journal of the American Chemical Society, 2018-11, Vol.140 (45), p.15206-15218

2018

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Strong optical response and light emission from a monolayer molecular crystal

Nature communications, 2019-12, Vol.10 (1), p.5589-9, Article 5589

2019

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Potassium Acetate-Catalyzed Double Decarboxylative Transannulation To Access Highly Functionalized Pyrroles

Organic letters, 2020-12, Vol.22 (24), p.9585-9590

2020

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Mechanism of Silver-Mediated Geminal Difluorination of Styrenes with a Fluoroiodane Reagent: Insights into Lewis-Acid-Activation Model

Organic letters, 2016-12, Vol.18 (23), p.6128-6131

2016

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How app-based ride-hailing services influence travel behavior: An empirical study from China

International journal of sustainable transportation, 2020-07, Vol.14 (7), p.554-568

2020

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A design optimized prime editor with expanded scope and capability in plants

Nature plants, 2022-01, Vol.8 (1), p.45-52

2022

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Dietary luteolin protects against HgCl2-induced renal injury via activation of Nrf2-mediated signaling in rat

Journal of inorganic biochemistry, 2018-02, Vol.179, p.24-31

2018

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Loss of miR-31-5p drives hematopoietic stem cell malignant transformation and restoration eliminates leukemia stem cells in mice

Science translational medicine, 2022-01, Vol.14 (629), p.eabh2548

2022

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Function, mechanism and drug discovery of ubiquitin and ubiquitin-like modification with multiomics profiling for cancer therapy

Tryptanthrin targets GSTP1 to induce senescence and increases the susceptibility to apoptosis by senolytics in liver cancer cells

Variants in the IL7RA gene confer susceptibility to multiple sclerosis in Caucasians: evidence based on 9734 cases and 10436 controls

A(H2N2) and A(H3N2) influenza pandemics elicited durable cross-reactive and protective antibodies against avian N2 neuraminidases

Silibinin, a potential fasting mimetic, inhibits hepatocellular carcinoma by triggering extrinsic apoptosis

Andrographolide Inhibits ER-Positive Breast Cancer Growth and Enhances Fulvestrant Efficacy via ROS-FOXM1-ER-α Axis

Amino acids in the polymerase complex of shorebird-isolated H1N1 influenza virus impact replication and host-virus interactions in mammalian models

Non‐invasive omics analysis delineates molecular changes in water‐only fasting and its sex‐discriminating features in metabolic syndrome patients

Five‐day water‐only fasting decreased metabolic‐syndrome risk factors and increased anti‐aging biomarkers without toxicity in a clinical trial of normal‐weight individuals

The Essential Role of Bond Energetics in C–H Activation/Functionalization

Self-preservation strategy for approaching global warming targets in the post-Paris Agreement era

Grape seed procyanidin extract protects against Pb-induced lung toxicity by activating the AMPK/Nrf2/p62 signaling axis

Uncertainties in the technological pathway towards low-carbon freight transport under carbon neutral target in China

Regulation of Sirt1/Nrf2/TNF-α signaling pathway by luteolin is critical to attenuate acute mercuric chloride exposure induced hepatotoxicity

NRF2 activation suppresses motor neuron ferroptosis induced by the SOD1G93A mutation and exerts neuroprotection in amyotrophic lateral sclerosis

Naringenin alleviates myocardial ischemia/reperfusion injury by regulating the nuclear factor-erythroid factor 2-related factor 2 (Nrf2) /System xc-/ glutathione peroxidase 4 (GPX4) axis to inhibit ferroptosis

Chiral Spiro Phosphoric Acid-Catalyzed Friedel–Crafts Conjugate Addition/Enantioselective Protonation Reactions

Mechanism and Origins of Chemo- and Stereoselectivities of Aryl Iodide-Catalyzed Asymmetric Difluorinations of β-Substituted Styrenes

Strong optical response and light emission from a monolayer molecular crystal

Potassium Acetate-Catalyzed Double Decarboxylative Transannulation To Access Highly Functionalized Pyrroles

Mechanism of Silver-Mediated Geminal Difluorination of Styrenes with a Fluoroiodane Reagent: Insights into Lewis-Acid-Activation Model

How app-based ride-hailing services influence travel behavior: An empirical study from China

A design optimized prime editor with expanded scope and capability in plants

Dietary luteolin protects against HgCl2-induced renal injury via activation of Nrf2-mediated signaling in rat

Loss of miR-31-5p drives hematopoietic stem cell malignant transformation and restoration eliminates leukemia stem cells in mice

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