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Chemical and structural lessons from recent successes in protein–protein interaction inhibition (2P2I)

Current opinion in chemical biology, 2011-08, Vol.15 (4), p.475-481

2011

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Structural Basis for the Interaction between Golgi Reassembly-stacking Protein GRASP55 and Golgin45

The Journal of biological chemistry, 2017-02, Vol.292 (7), p.2956-2965

2017

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2P2Idb: a structural database dedicated to orthosteric modulation of protein-protein interactions

Nucleic acids research, 2013-01, Vol.41 (Database issue), p.D824-D827

2013

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Which decreases in air pollution should be targeted to bring health and economic benefits and improve environmental justice?

Environment international, 2019-08, Vol.129 (August 2019), p.538-550

2019

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Coronavirus Nsp10, a Critical Co-factor for Activation of Multiple Replicative Enzymes

The Journal of biological chemistry, 2014-09, Vol.289 (37), p.25783-25796

2014

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Atomic analysis of protein-protein interfaces with known inhibitors: the 2P2I database

PloS one, 2010-03, Vol.5 (3), p.e9598-e9598

2010

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Structural Basis for the Interaction between the Golgi Reassembly-stacking Protein GRASP65 and the Golgi Matrix Protein GM130

The Journal of biological chemistry, 2015-10, Vol.290 (44), p.26373-26382

2015

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The fraction of lung cancer incidence attributable to fine particulate air pollution in France: Impact of spatial resolution of air pollution models

Environment international, 2018-12, Vol.121 (Pt 2), p.1079-1086

2018

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2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein-protein interactions

Database : the journal of biological databases and curation, 2016, Vol.2016, p.baw007

2016

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CD47-SIRPα Controls ADCC Killing of Primary T Cells by PMN Through a Combination of Trogocytosis and NADPH Oxidase Activation

Frontiers in immunology, 2022-06, Vol.13, p.899068-899068

2022

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Estimation of exposure to atmospheric pollutants during pregnancy integrating space–time activity and indoor air levels: Does it make a difference?

Environment international, 2015-11, Vol.84, p.161-173

2015

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From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia

Nature communications, 2023-05, Vol.14 (1), p.3079-3079, Article 3079

2023

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Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis

PLoS genetics, 2017-06, Vol.13 (6), p.e1006803-e1006803

2017

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Crystal structure of the vaccinia virus DNA polymerase holoenzyme subunit D4 in complex with the A20 N-terminal domain

PLoS pathogens, 2014-03, Vol.10 (3), p.e1003978-e1003978

2014

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Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology

Nature communications, 2017-11, Vol.8 (1), p.1420-11, Article 1420

2017

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Protein-protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein

Proceedings of the National Academy of Sciences - PNAS, 2007-12, Vol.104 (49), p.19256-19261

2007

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Protein–Protein Interaction Inhibition (2P2I)-Oriented Chemical Library Accelerates Hit Discovery

ACS chemical biology, 2016-08, Vol.11 (8), p.2140-2148

2016

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Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins

Nature structural & molecular biology, 2003-09, Vol.10 (9), p.751-756

2003

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Modified Cap Group Suberoylanilide Hydroxamic Acid Histone Deacetylase Inhibitor Derivatives Reveal Improved Selective Antileukemic Activity

Journal of medicinal chemistry, 2010-04, Vol.53 (8), p.3038-3047

2010

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Prevalence, specificity and determinants of lipid-interacting PDZ domains from an in-cell screen and in vitro binding experiments

PloS one, 2013-02, Vol.8 (2), p.e54581-e54581

2013

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Daily volume of cases in emergency call centers: construction and validation of a predictive model

Scandinavian journal of trauma, resuscitation and emergency medicine, 2017-08, Vol.25 (1), p.86-86, Article 86

2017

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2P2Ichem: focused chemical libraries dedicated to orthosteric modulation of protein–protein interactions

MedChemComm, 2013-05, Vol.4 (5), p.797-809

2013

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Protein-protein interaction inhibition (2P2I): fewer and fewer undruggable targets

Combinatorial chemistry & high throughput screening, 2009-12, Vol.12 (10), p.968-983

2009

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Searching for the Holy Grail; protein-protein interaction analysis and modulation

EMBO reports, 2012-10, Vol.13 (10), p.877-879

2012

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An integrative in silico methodology for the identification of modulators of macrophage migration inhibitory factor (MIF) tautomerase activity

Bioorganic & medicinal chemistry, 2010-07, Vol.18 (14), p.5425-5440

2010

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Chemical and structural lessons from recent successes in protein–protein interaction inhibition (2P2I)

Structural Basis for the Interaction between Golgi Reassembly-stacking Protein GRASP55 and Golgin45

2P2Idb: a structural database dedicated to orthosteric modulation of protein-protein interactions

Which decreases in air pollution should be targeted to bring health and economic benefits and improve environmental justice?

Coronavirus Nsp10, a Critical Co-factor for Activation of Multiple Replicative Enzymes

Atomic analysis of protein-protein interfaces with known inhibitors: the 2P2I database

Structural Basis for the Interaction between the Golgi Reassembly-stacking Protein GRASP65 and the Golgi Matrix Protein GM130

The fraction of lung cancer incidence attributable to fine particulate air pollution in France: Impact of spatial resolution of air pollution models

2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein-protein interactions

CD47-SIRPα Controls ADCC Killing of Primary T Cells by PMN Through a Combination of Trogocytosis and NADPH Oxidase Activation

Estimation of exposure to atmospheric pollutants during pregnancy integrating space–time activity and indoor air levels: Does it make a difference?

From a drug repositioning to a structure-based drug design approach to tackle acute lymphoblastic leukemia

Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis

Crystal structure of the vaccinia virus DNA polymerase holoenzyme subunit D4 in complex with the A20 N-terminal domain

Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology

Protein-protein interaction inhibition (2P2I) combining high throughput and virtual screening: Application to the HIV-1 Nef protein

Protein–Protein Interaction Inhibition (2P2I)-Oriented Chemical Library Accelerates Hit Discovery

Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins

Modified Cap Group Suberoylanilide Hydroxamic Acid Histone Deacetylase Inhibitor Derivatives Reveal Improved Selective Antileukemic Activity

Prevalence, specificity and determinants of lipid-interacting PDZ domains from an in-cell screen and in vitro binding experiments

Daily volume of cases in emergency call centers: construction and validation of a predictive model

2P2Ichem: focused chemical libraries dedicated to orthosteric modulation of protein–protein interactions

Protein-protein interaction inhibition (2P2I): fewer and fewer undruggable targets

Searching for the Holy Grail; protein-protein interaction analysis and modulation

An integrative in silico methodology for the identification of modulators of macrophage migration inhibitory factor (MIF) tautomerase activity

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